These data provide an additional dimension in which to characterize gene regulatory landscapes by mapping CREs to their putative target genes. We address these ...
Missing: Computational | Show results with:Computational
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May 15, 2023 · The mammalian skull is an excellent model to study morphological evolution, especially in the context of divergence of cis-regulatory sequences.
Here we introduce CRE analysis by sequencing (CRE-seq), a high-throughput method for producing and testing large numbers of reporter genes in mammalian cells.
Missing: landscape. | Show results with:landscape.
Cis-regulatory elements (CREs, e.g., promoters and enhancers) regulate gene expression, and variants within CREs can modulate disease risk.
May 29, 2024 · Cis-regulatory elements (CREs) interact with trans regulators to orchestrate gene expression, but how transcriptional regulation is ...
Improvements in DNA sequencing technologies have made it possible to determine the genetic makeup of many organisms. Computational analyses of the massive ...
May 27, 2021 · In multicellular organisms, cis-regulatory elements (CREs) lie at the center of transcriptional regulation and cell fate decisions. CREs are ...
Missing: mammalian | Show results with:mammalian
Apr 25, 2024 · Therefore, in this study, we aim at the systematic identification of gene regulatory sequences and annotation of their function in terms of ...
Missing: mammalian | Show results with:mammalian
May 27, 2021 · The datasets and analysis tools provided here open the door toward a systematic understanding of how cis- and trans-regulators determine cell ...
Missing: mammalian | Show results with:mammalian
Mar 31, 2016 · The three-dimensional (3D) spatial organization of mammalian chromosomes in vivo is a topic of fundamental importance in cell biology [1–5].