CypRules is a web server built based on the models tested in this study, to provide a platform for virtually screening compound inhib- ition at each P450 endpoint. The web server not only predicts the in- hibition of P450 endpoints, it also provides structural rulesets that contribute towards predicted inhibitions.
Jan 22, 2015
Jun 1, 2015 · A rule-based CYP inhibition prediction online server, CypRules, was created based on predictive models generated by the rule-based C5.0 algorithm.
A rule-based CYP inhibition prediction online server, CypRules, was created based on predictive models generated by the rule-based C5.0 algorithm.
In this work, a rule-based CYP inhibition prediction online server, CypRules, was created based on predictive models generated by the rule-based C5.0 algorithm.
A rule-based CYP inhibition prediction online server, CypRules, was created based on predictive models generated by the rule-based C5.0 algorithm.
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Cytochrome P450 (CYPs) are the major enzymes involved in drug metabolism and bioactivation. Inhibition models were constructed for five of the most popular ...
A newer version of the freely accessible CYP prediction server, CypRules, is presented here as a result of the aforementioned improvements. Publication types.
A newer version of the freely accessible CYP prediction server, CypRules, is presented here as a result of the aforementioned improvements. ACS Publications.
CypRules: a rule-based P450 inhibition prediction server · Chemistry, Computer Science. Bioinform. · 2015.
Cytochrome P450 (CYPs) are the major enzymes involved in drugmetabolism and bioactivation. Five of the most popular CYP superfamilyenzymes in hum |