Computational design of drug candidates for influenza A virus subtype H1N1 by inhibiting the viral neuraminidase-1 enzyme. Acta Pharm. 2014 Jun;64(2):157-72 ...
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In this study, a QSAR model of neuraminidase (NA) type 1 (N1) provides an access. The pharmacophore map of N1 contained two hydrogen bond acceptor features, one ...
Both zanamivir (Relenza) and oseltamivir (Tamiflu) are neuraminidase inhibitors (Collins et al., 2008, Ho et al., 2007). Influenza A virus subtype H1N1 is the ...
In this study, a QSAR model and pharmacophore map of neuraminidase (NA) type 1 (N1) contained two hydrogen bond acceptor features, one hydrogen bond donor ...
In this study, a QSAR model of neuraminidase (NA) type 1 (N1) provides an access. The pharmacophore map of N1 contained two hydrogen bond acceptor features, one ...
Aug 23, 2023 · Pimodivir has excellent inhibitory activity against IAV, including H1N1 pdm09, H3N2, and H5N1 subtypes, as well as viruses resistant to ...
Currently available anti-influenza virus drugs target either the viral M2 ion channel (Amantadine and Rimantadine) or the viral neuraminidase (oseltamivir and ...
drugs a viable alternative. 158. U. S. F. Tambunan et al.: Computational design of drug candidates for influenza A virus subtype H1N1 by inhibiting the viral.