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Computational design of drug candidates for influenza A virus subtype H1N1 by inhibiting the viral neuraminidase-1 enzyme. Acta Pharm. 2014 Jun;64(2):157-72 ...
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In this study, a QSAR model of neuraminidase (NA) type 1 (N1) provides an access. The pharmacophore map of N1 contained two hydrogen bond acceptor features, one ...
Both zanamivir (Relenza) and oseltamivir (Tamiflu) are neuraminidase inhibitors (Collins et al., 2008, Ho et al., 2007). Influenza A virus subtype H1N1 is the ...
In this study, a QSAR model and pharmacophore map of neuraminidase (NA) type 1 (N1) contained two hydrogen bond acceptor features, one hydrogen bond donor ...
Drug Design for the Influenza A Virus Subtype H1N1. from www.sciencedirect.com
A single-dose administration of ZA-cholesterol protected mice from lethal attack of influenza A virus (wild-type or H1N1-H274Y), conferring resistance to ...
Drug Design for the Influenza A Virus Subtype H1N1. from www.nature.com
Aug 25, 2017 · At present, two classes of anti-influenza viral medicines have been approved: M2 inhibitors (amantadine and rimantadine) and neuraminidase (NA) ...
In this study, a QSAR model of neuraminidase (NA) type 1 (N1) provides an access. The pharmacophore map of N1 contained two hydrogen bond acceptor features, one ...
Aug 23, 2023 · Pimodivir has excellent inhibitory activity against IAV, including H1N1 pdm09, H3N2, and H5N1 subtypes, as well as viruses resistant to ...
Currently available anti-influenza virus drugs target either the viral M2 ion channel (Amantadine and Rimantadine) or the viral neuraminidase (oseltamivir and ...
drugs a viable alternative. 158. U. S. F. Tambunan et al.: Computational design of drug candidates for influenza A virus subtype H1N1 by inhibiting the viral.