In this paper, the convergent behavior of GENET is thoroughly analyzed and its learning strategy is generalized. The obtained results can shed light on choosing ...

In this paper, the convergent behavior of GENET is thoroughly analyzed and its learning strategy is generalized. The obtained results can shed light on choosing.

Apr 6, 2007 · We describe a very general approach to the problem of assessing genetic background diversity that extends the analysis of molecular variance (AMOVA) strategy.

This gene-set analysis also uses a regression structure to allow generalization to analysis of continuous properties of genes and simultaneous analysis of ...

Sep 14, 2018 · The aim of gene-set analysis (GSA) is to uncover functional and biological properties of genes involved in the genetic aetiology of a phenotype.

Pathway analysis, also known as gene-set enrichment analysis, is a multi-locus analytic strategy that integrates a-priori biological knowledge into the ...

Jan 24, 2007 · Here we study the properties of the topological overlap measure (TOM) and propose a generalization that enriches TOM's sensitivity to longer ...

Jul 3, 2018 · Abstract. A common complementary strategy in Genome-Wide Association Studies (GWAS) is to perform Gene Set Analysis (GSA), which tests for ...

To study the properties of the proposed mixed models, we simulated both null gene sets, for which the disease status of the samples were generated randomly ...

We compare GBJ to popular alternatives through simulation and re-analysis of summary statistics from a large breast cancer GWAS, and we show how GBJ can ...