After decades of searching, only 10-20% of all cancer genes are known. Identifying candidate cancer genes are still a central aim of cancer research.
Identifying candidate cancer genes are still a central aim of cancer research. In current high throughput studies of screening somatic mutations in cancer ...
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Current methods for identifying candidate cancer genes based on gene mutation frequencies tend to find cancer genes with high mutation frequencies. However, ...
Missing: Occurring Profiling.
Jun 18, 2024 · Hierarchical clustering of cancers based on the presence of identified driver mutations and their respective q value demonstrated clustering ...
Nov 15, 2019 · Genomic studies from cancer patients have identified epigenetic and genetic regulators – such as methylation marks, somatic mutations, and ...
Jan 4, 2024 · Somatic mutations contribute to cancer development by altering the activity of enhancers. In the study, a total of 135 mutation-driven ...
Identifying Candidate Cancer Genes Based on Their Somatic Mutations Co-Occurring with Cancer Genes in Cancer Genome Profiling.
Dec 19, 2023 · Recently, studies have begun exploring the interactions between germline and somatic mutations in cancer. Notably, research has revealed that ...
To evaluate the role of mutations in overall survival (OS) and treatment outcomes, we analyzed 957 metastatic patients with seven major cancer types who had ...
Original article. Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced ...