Results: In this article, we propose a novel framework for haplotype inference from short read sequencing that leverages multi-single nucleotide polymorphic ...
People also ask
How can SNP haplotypes be determined?
What is haplotype inference?
Can individual SNPs or haplotypes help us identify anything about nearby sequences of DNA?
What is the difference between DNA and haplotype?
A novel framework for haplotype inference from short read sequencing that leverages multi-single nucleotide polymorphic reads together with a reference ...
The basis of our approach is a new probabilistic model that finds the most likely haplotype segments from the reference panel to explain the short read ...
Table 1. Open in new tab. Comparison between IMPUTE*, Hap-SeqX and HARSH on a HapMap dataset with 1 donor individual, 59 reference individuals and 35 421 SNPs ...
Table 2. Open in new tab. Genotyping and switching ... Note: Read length is fixed to be 1000 bp. ... data in your web browser. This storage is often ...
Haplotype assembly from sequenced reads of an individual genome has several advantages over haplotypes obtained by computationally phasing SNP genotypes from a ...
Improved haplotype inference by exploiting long-range linking and ...
www.nature.com › ... › articles
Sep 16, 2020 · However, these methods are still contiguity-based, relying on sequencing reads that span two or more heterozygous SNPs. Moreover, even the range ...
Missing: polymorphisms | Show results with:polymorphisms
The first step of HATCHet2 identifies heterozygous germline single-nuclotide polymorphisms (SNPs) from the matched normal sample using a reference database ( ...
... Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data. Bioinformatics 29(18), 2245–2252 (2013).
Sep 25, 2014 · ... Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data. Bioinformatics. 2013, 29 ...