Sep 27, 2017 · De novo protein design holds promise for creating small stable proteins with shapes customized to bind therapeutic targets.
De novo protein design holds promise for creating small stable proteins with shapes customized to bind therapeutic targets. We describe a massively parallel ...
People also ask
What is a de novo protein design?
What are the advantages of de novo design?
What is the de novo protein hypothesis?
Why is protein design important?
Abstract. De novo protein design holds promise for creating small stable proteins with shapes customized to bind therapeutic targets.
Sep 27, 2017 · Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed ...
Oct 5, 2017 · We describe a massively parallel approach for designing, manufacturing and screening mini-protein binders, integrating large-scale computational ...
People also search for
The Baker lab and numerous talented collaborators published in Nature that it is now possible to conduct “Massively parallel de novo protein design for targeted ...
May 6, 2023 · Abstract. Recently it has become possible to de novo design high affinity protein binding proteins from target structural information alone.
Authors: Aaron Chevalier; Daniel-Adriano Silva; Gabriel J. Rocklin; Derrick R. Hicks; Renan Vergara; Patience Murapa; Steffen M. Bernard; Lu Zhang; Kwok-Ho ...
"Massively parallel de novo protein design for targeted therapeutics". DOI: 10.1038/nature23912. Supplementary Information. Archive of designs, Rosetta ...
De novo design strategies stand as an essential tool to aid the exploration of the sequence space and thereby enabling the creation of new protein structures ...