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Connexin 43 (Cx43), the major component of gap junc- tions in the ventricle, is responsible for electrical impulse transmission between ventricular ...
Aug 28, 2024 · Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia. November 2023. DOI ...
Nov 15, 2023 · Evaluation of the effect of CX43 remodeling and fibrosis deposition on ventricular electrophysiology and arrhythmic risk. (A) Violin plot of ...
Feb 24, 2012 · We hypothesized that reduced connexin43 (Cx43) expression is responsible for enhanced fibrosis in the remodeled heart, resulting in an arrhythmogenic substrate.
May 31, 2021 · Both gap junctional remodeling and interstitial fibrosis have been linked to impaired electrical conduction velocity (CV) and fatal ventricular arrhythmias in ...
Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia. Conference Paper. Full-text ...
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Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia. L García-Mendívil, M Pérez-Zabalza ...
The structural correlate of AF comprises extensive concomitant remodeling of mechanical and electrical junctions, reduction of Cx43, heterogenous distribution ...
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Immunoblotting revealed that AF did not induce any significant change in Cx43 content in human atria. In contrast, a 2.7-fold increase in expression of Cx40 was ...
Apr 13, 2016 · Fibrosis and altered gap junctional coupling are key features of ventricular remodelling and are associated with abnormal electrical impulse ...
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