Reconstructing the pre-doubling genome. Authors: Nadia El-Mabrouk.

The problem is to calculate the minimum number of translocations required to transform a given rearranged du- plicated genome G into some perfect duplicated.

We simulate data sets starting with a pre-duplication 2-chromosome, 200-gene genome at the root of the tree and performing a number of gene losses and a maximum ...

Jul 12, 2017 · AbstractMotivation. It has been argued that whole-genome duplication (WGD) exerted a profound influence on the course of evolution.

Long-standing efforts have been made to reconstruct the ancestral teleost karyotype before the whole-genome duplication (Jaillon et al. 2004;Kasahara et al ...

Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus.

This hypothesis is clearly false for species containing several copies of highly paralogous genes, e.g. multigene families. One of the most important regional ...

We present exact algorithms for reconstructing the ancestral doubled genome in linear time, minimizing the number of rearrangement mutations required to derive ...

Genome duplication: A linear-time exact algorithm for reconstructing a pre-doubling ancestral genome in case of reversals, translocations and reversals+ ...

Mar 4, 2019 · In this study, we use Mlgo to reconstruct the ancestral genomes from syntenic-block data for selected legume species.