To address this problem, we developed “reference-assisted chromosome assembly” (RACA), an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into longer chromosomal fragments using comparative genome information and paired-end reads.
Jan 10, 2013
Jan 29, 2013 · We developed reference-assisted chromosome assembly (RACA), an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into ...
People also ask
What is reference based genome assembly?
What is chromosome assembly?
What are the two types of genome assembly?
What is a good genome assembly?
We developed “reference-assisted chromosome assembly” (RACA), an algorithm to reliably order and orient sequence scaffolds generated by NGS and assemblers into ...
Chromosomer is a reference-assisted assembly tool for producing draft chromosome sequences. It provides the following routines.
Oct 28, 2019 · We present RaGOO, a reference-guided contig ordering and orienting tool that leverages the speed and sensitivity of Minimap2 to accurately achieve chromosome- ...
Evaluated results indicate that RACA will significantly facilitate the study of chromosome evolution and genome rearrangements for the large number of ...
We developed Ragout 2, a reference-assisted assembly tool that works for large and complex genomes.
Aug 22, 2016 · We developed Chromosomer – a reference-based genome arrangement tool, which rapidly builds chromosomes from genome contigs or scaffolds using their alignments.
Our work demonstrates that reference-assisted assembly has the potential to enhance contiguity and completeness of existing insect genomic resources.
Feb 17, 2021 · We introduce a new method, Aquila, which uses a high-quality reference sequence to perform assembly in small chunks for both haplotypes, ...