This approach coupled with the DNF technique has yielded results for several diseases with some of the highest sensitivities seen so far and specificities that ...
Abstract. Recent large scale genome-wide association studies have been considered to hold promise for unraveling the genetic etiology of com- plex diseases.
has the best odds ratio, a criterion often used in disease association studies [5]. ... is a recently developed new methodology called discretized network flow ( ...
The multiple SNP selection problem for determining genetic risk profiles of certain diseases is formulated by formulating novel 0/1 IP formulations for this ...
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Selection of Multiple SNPs in Case-Control Association Study Based on a Discretized Network Flow Approach. Shantanu Dutt, Yang Dai, Huan Ren and Joel ...
In this paper, I have developed a novel SNP selection procedure within the framework of multi-stage designs. Based on data from stage 1, the method explicitly ...
Statistical fine-mapping is conducted in each region, using one of the methods illusrated in Figure 2. The SNPs selected from fine-mapping are then annotated ...
Jan 1, 2014 · Extracting predictive SNPs in Crohn's disease using a vacillating genetic algorithm and a neural classifier in case–control association studies.
... Ren, Joel Fontanarosa. Selection of Multiple SNPs in Case-Control Association Study Using a Discretized Network Flow Approach 211-223. [Crossref]
An efficient strategy based on two-stage analysis that combines a single-locus approach with a Goodness-Of-Fit (GOF) test in stage one, and selects a ...