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Aug 23, 2013 · With this method, the substrates of Class I HDACs were systematically determined from these known acetylation sites, and a list of potential ...
Aug 23, 2013 · In this research, Class I histone deacetylases (HDACs) substrates were manually obtained, and sequence features of deacetylation sites were ...
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Aug 23, 2013 · Abstract. Lysine acetylation is a common post-translational modification of histone and non-histone proteins. This process has.
In this research, Class I histone deacetylases (HDACs) substrates were manually obtained, and sequence features of deacetylation sites were analyzed. We found ...
Aug 22, 2022 · In summary, our systematic study revealed isoform-specific roles of HDAC1/2/3 catalytic functions. We suggest that targeted genetic inactivation ...
HDACs are capable of catalyzing the removal of the N-acetyl group from acetylated lysine residues in histones and non-histone proteins [17,18]. The substrates ...
Apr 25, 2016 · Class I histone deacetylases (HDACs) are enzymes involved in 'epigenetic' gene regulation through controlling the acetylation state of lysine ...
Aug 4, 2014 · In conclusion, we have identified several novel substrates of HDAC8 by taking an unbiased approach coupling chemical tools with acetylome ...
Jan 19, 2022 · Here, we report the systematic evaluation of zinc- and nicotinamide adenine dinucleotide–dependent histone deacetylases (HDACs) for their ...
The first column is different cutoff levels. The second column is the number of known deacetylated peptides with P-values less than or equal to the cutoff ...