Using genetic data to identify and validate drug targets has been shown to reduce failure rates in clinical drug development. Widely used techniques include loss-of-function analysis, colocalization, and Mendelian randomisation.
We propose a new method for identifying and validating drug targets by using gene networks, which are estimated from cDNA microarray gene expression profile ...
We propose a new method for identifying and validating drug targets by using gene networks, which are estimated from cDNA microarray gene expression profile ...
In this chapter, we describe computational methods for identifying and validating drug target genes based on the gene networks estimated from microarray gene ...
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We propose a new method for identifying and validating drug targets by using gene networks, which are estimated from cDNA microarray gene expression profile ...
May 10, 2022 · Artificial intelligence is an advanced method to identify novel anticancer targets and discover novel drugs from biology networks.
Dec 1, 2020 · We conclude that network propagation of genetic evidence can be used for drug target identification.
The complete genome sequences have provided a plethora of potential drug targets. Gene network technique holds the promise of providing a conceptual ...
We propose a new method for identifying and validating drug targets by using gene networks, which are estimated from cDNA microarray gene expression profile ...
Nov 4, 2022 · Network-based methods predict novel drug target genes or drugs for repositioning through multiple algorithms. Compared to molecular docking- ...
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