Jun 15, 2016 · The standard statistical method to determine whether a gene is an eGene requires association testing at all nearby variants and the permutation ...
Jun 11, 2016 · In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical ...
Abstract. Motivation: Expression quantitative trait loci (eQTLs) are genetic variants that affect gene expres- sion. In eQTL studies, one important task is ...
Sep 26, 2016 · Our group developed a novel method for detecting eGenes, the genes whose expression levels are associated with variation at a particular ...
A novel eGene detection method that considers this empirical evidence and thereby increases the statistical power and discovered 50% more candidate eGenes ...
Jun 16, 2016 · Distance from TSS appears to be the most important annotation; specifically, using this annotation,. our method discovered 50% more candidate ...
Duration: 16:27
Posted: Aug 26, 2020
Posted: Aug 26, 2020
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Using genomic annotations increases statistical power to detect eGenes. Dat ... Using genomic annotations increases statistical power to detect eGenes.
In this paper, we have introduced a new method called T-GEN, which leverages epigenetic signals to improve gene expression imputation and identify trait- ...
In this paper, we derive the statistical power distribution across causal SNPs under the assumption of a point-normal effect size distribution. We demonstrate ...