Objective: To investigate the relationship between intima-media thicknesses (IMT) of carotid and ... more Objective: To investigate the relationship between intima-media thicknesses (IMT) of carotid and superficial femoral arteries and coronary artery calcium index quantified using Agatston score. Materials and Methods: Cardiac multidetector computed tomography (MDCT) angiography of 75 patients were included in the study. Coronary artery calcium scores were measured using a workstation. Calcium scores were calculated according to the Agatston method. Bilateral carotid artery and superficial femoral artery IMTs were obtained by B-mode ultrasound. All patients were divided into three groups according to Agatston scores. 25 patients with 0 Agatston score were included to first group. 25 patients with 1-100 and 25 patients with more than 101 Agatston score were included to second and third group, respectively. Oneway Anova, t test and Post HocTukey HSD test were used for statistical analysis. Values of P< 0.05 were considered statistically significant. Results: There was a significant re...
tube voltage increases the diagnostic performance of dual-energy computed tomography in patients ... more tube voltage increases the diagnostic performance of dual-energy computed tomography in patients with acute appendicitis.
Poster: "EuroSafe Imaging 2018 / ESI-0053 / Pearls and pitfalls for fast imaging, low dose a... more Poster: "EuroSafe Imaging 2018 / ESI-0053 / Pearls and pitfalls for fast imaging, low dose and high quality in emergency radiology" by: "M. R. Onur, E. Akpinar, I. Idilman, M. N. Ozmen, D. Akata; Hacettepe University Faculty of Medicine Department of Radiology Ankara/TR"
Peripelvic and periureteric areas are frequently overlooked in the imaging evaluations of the uri... more Peripelvic and periureteric areas are frequently overlooked in the imaging evaluations of the urinary system on computed tomography and magnetic resonance imaging. Several neoplastic and non-neoplastic disorders and diseases including lipomatosis, angiomyolipoma and angiolipomatous proliferation, vascular lesions, lymphangiomatosis, Rosai–Dorfman disease, Erdheim–Chester disease, extramedullary hematopoiesis, IgG4-related disease, lymphoma, mesenchymal tumors, trauma, and Antopol–Goldman lesion may involve these areas. Differentiation of these benign or malignant pathologies among themselves and from primary renal pathologies is of utmost importance to expedite the triage of patients for correct treatment approach. In this article, we aim to increase the awareness of the imaging specialists to the typical and atypical imaging features of the entities affecting these areas.
Background. Amyand's hernia is rarely noted in children, and appendicitis caused by a foreign bod... more Background. Amyand's hernia is rarely noted in children, and appendicitis caused by a foreign body in Amyand's hernia is even rarer. Case. A 2-year-old girl presented with recurrent conglomerate lymph node enlargements and an abscess in the right groin existing for one year despite medical treatment. Direct radiography revealed a foreign body in the right inguinal region. Computed tomography showed a foreign body and soft tissue inflammation in the inguinal canal. Laparotomy was performed, and Amyand's hernia was diagnosed. A foreign body was found in the lumen of the appendix vermiformis causing perforated appendicitis. This case is presented because of its rarity and unusual clinical presentation. Conclusion. Amyand's hernia should be considered in paediatric cases with the history of recurrent inguinal abscesses.
106 alignant melanoma is a neoplasm that originates from melanocytes. The overall incidence of th... more 106 alignant melanoma is a neoplasm that originates from melanocytes. The overall incidence of this rare neoplasm has increased dramatically in recent years. Melanomas are serious and difficult to treat neoplasm and metastasis to liver, lung and brain can be seen with a poor survival rate.1 Recurrence of malignant melanoma after successful surgical treatment may not be seen for decades however it can recur even several years after the initial diagnosis with curative treatment.2
Sclerosing stromal tumor (SST) is a benign stromal tumor of the ovary. Preoperative diagnosis of ... more Sclerosing stromal tumor (SST) is a benign stromal tumor of the ovary. Preoperative diagnosis of this benign tumor mainly depends on imaging findings. Dynamic computed tomography (CT) and magnetic resonance imaging (MRI) show typical contrast enhancement of SST with peripheral enhancement in the early phase and centripetal progression in the delayed phases. We present the imaging findings of ultrasonography, ultrasound elastography, and dynamic MRI in the diagnosis of SST. Abdominal ultrasound elastography is a novel technique that depicts the stromal structure of SSTs by comparing the elasticity of the tumor and the myometrium using quantitative strain values.
A 50-year-old female patient presented to emergency department with severe epigastric pain. She h... more A 50-year-old female patient presented to emergency department with severe epigastric pain. She had pain for the last 4 days. Her history revealed that the patient had been diagnosed with osteosarcoma in the left femur 2 years ago and amputation of the leg above the lesion was performed. She also received adjuvant chemotherapy. During follow-up, a mass was identified in her esophagus in 2008 and biopsy revealed metastatic osteosarcoma. Upon admission to our department, laboratory examination was normal. Patient had severe dysphagia and mass related obstructed lumen of esophagus. After several unsuccessful esophagus dilatation attempts, a gastrostomy was opened in order to feed the patient. An abdominal computed tomography was performed after giving nonionic contrast material through the gastrostomy tube and intravenous contrast administration. There was a huge ossified mass in the mediastinum and epigastrium with invasion of the pleura and diaphragm (Fig. 1). Metastatic mass was encircling the aorta but not invading its wall (Fig. 2). The stomach was also compressed by the mass. The density measurement of this mass revealed 991 HU indicating calcification (Fig. 1), whereas the density measured over the intestinal loops was 324 HU. No esophageal perforation was present. Palliative treatment including chemotherapy and feeding via gastrostomy tube was administered to the patient. She died because of metastatic osteosarcoma 3 months after hospitalization.
Citations to scholarly items are building bricks for multidisciplinary science communication. Cit... more Citations to scholarly items are building bricks for multidisciplinary science communication. Citation analyses are currently influencing individual career advancement and ranking of academic and research institutions worldwide. This article overviews the involvement of scientific authors, reviewers, editors, publishers, indexers, and learned associations in the citing and referencing to preserve the integrity of science communication. Authors are responsible for thorough bibliographic searches to select relevant references for their articles, comprehend main points, and cite them in an ethical way. Reviewers and editors may perform additional searches and recommend missing essential references. Publishers, in turn, are in a position to instruct their authors over the citations and references, provide tools for validation of references, and open access to bibliographies. Publicly available reference lists bear important information about the novelty and relatedness of the scholarly items with the published literature. Few editorial associations have dealt with the issue of citations and properly managed references. As a prime example, the International Committee of Medical Journal Editors (ICMJE) issued in December 2014 an updated set of recommendations on the need for citing primary literature and avoiding unethical references, which are applicable to the global scientific community. With the exponential growth of literature and related references, it is critically important to define functions of all stakeholders of science communication in curbing the issue of irrational and unethical citations and thereby improve the quality and indexability of scholarly journals.
The use of radiological imaging in urological cancers is increasing with improvements in imaging ... more The use of radiological imaging in urological cancers is increasing with improvements in imaging technologies and implementation of these techniques to clinical scenarios. Ultrasonography, computed tomography, and magnetic resonance imaging have enormous potentials in the diagnosis, staging, and surveillance of urological cancers. Emerging imaging techniques enable morphologic assessment of urological cancers with high spatial and contrast resolution. Functional imaging techniques reveal microstructure of tumors which can be used in the diagnosis, prediction of prognosis, and assessment of response to treatment and surveillance of tumors. Biopsyless diagnosis may be possible in the future particularly for renal and prostate tumors. In this chapter, current status of urooncologic imaging will be reviewed.
Kidney neoplasms are common clinical disorders now being detected in even great-er numbers due to... more Kidney neoplasms are common clinical disorders now being detected in even great-er numbers due to the widespread use of cross-sectional imaging. Benign kidney neoplasms, once thought to be highly unusual, are being diagnosed in ever increas-ing numbers. In one series, 16.1 % of patients who underwent partial nephrectomy for a presumed solitary renal cell carcinoma turned out to have a benign diagnosis in the final pathological analysis (1). Recent developments on computed tomography (CT) and mag-netic resonance imaging (MRI) have limited value in differentiation between benign and malignant renal masses. Diffusion MRI studies yielded significantly different apparent dif-fusion coefficient (ADC) values between benign and malignant renal masses. These studies mostly evaluated the different ADC values between oncocytoma/angiomyolipoma and re-nal cell carcinomas (2). The role of ADC values in differentiation between uncommon be-nign renal masses and malignant renal masses has not been w...
Background: To explore the clinical significance of baseline volumetric body composition paramete... more Background: To explore the clinical significance of baseline volumetric body composition parameters evaluated with computerized tomography (CT) and their changes after 3-4 months from treatment initiation of targeted therapy in patients with metastatic renal cell carcinoma (mRCC). Method: This study included 108 Caucasian mRCC patients (Male/Female: 77/31) treated with targeted therapy. Volumetric body composition parameters including total adipose tissue index (TATI), subcutaneous adipose tissue index (SATI), visceral adipose tissue index (VATI) and skeletal muscle index (SMI) values were depicted from CT images at third lumbar vertebra level through volumetric measurement software. Kaplan-Meier method and the long test were used for estimation of progression free survival (PFS) and overall survival (OS). Univariate and multivariate analyses were done to determine the associations between clinic-pathologic variables including VBC and survival outcomes. Results: The median PFS and O...
Poster: "EuroSafe Imaging 2018 / ESI-0052 / Optimisation of CT protocols in abdominal emerge... more Poster: "EuroSafe Imaging 2018 / ESI-0052 / Optimisation of CT protocols in abdominal emergencies" by: "M. R. Onur, I. Idilman, E. Akpinar, M. N. Ozmen, D. Akata; Hacettepe University Faculty of Medicine Department of Radiology Ankara/TR"
Abdominal pain is one of the most common complaints of patients presenting to the emergency depar... more Abdominal pain is one of the most common complaints of patients presenting to the emergency department. Among the patients with abdominal pain, appendicitis is the most common surgical disorder. Appendicitis presenting with left lower quadrant pain may result in false-negative diagnosis. Left sided appendicitis occurs in association with situs inversus and intestinal malrotation. We describe a rare case of left sided appendicitis with situs inversus totalis. Key Words: Appendicitis, Situs inversus, Ultrasonography
Objective: To investigate the relationship between intima-media thicknesses (IMT) of carotid and ... more Objective: To investigate the relationship between intima-media thicknesses (IMT) of carotid and superficial femoral arteries and coronary artery calcium index quantified using Agatston score. Materials and Methods: Cardiac multidetector computed tomography (MDCT) angiography of 75 patients were included in the study. Coronary artery calcium scores were measured using a workstation. Calcium scores were calculated according to the Agatston method. Bilateral carotid artery and superficial femoral artery IMTs were obtained by B-mode ultrasound. All patients were divided into three groups according to Agatston scores. 25 patients with 0 Agatston score were included to first group. 25 patients with 1-100 and 25 patients with more than 101 Agatston score were included to second and third group, respectively. Oneway Anova, t test and Post HocTukey HSD test were used for statistical analysis. Values of P< 0.05 were considered statistically significant. Results: There was a significant re...
tube voltage increases the diagnostic performance of dual-energy computed tomography in patients ... more tube voltage increases the diagnostic performance of dual-energy computed tomography in patients with acute appendicitis.
Poster: "EuroSafe Imaging 2018 / ESI-0053 / Pearls and pitfalls for fast imaging, low dose a... more Poster: "EuroSafe Imaging 2018 / ESI-0053 / Pearls and pitfalls for fast imaging, low dose and high quality in emergency radiology" by: "M. R. Onur, E. Akpinar, I. Idilman, M. N. Ozmen, D. Akata; Hacettepe University Faculty of Medicine Department of Radiology Ankara/TR"
Peripelvic and periureteric areas are frequently overlooked in the imaging evaluations of the uri... more Peripelvic and periureteric areas are frequently overlooked in the imaging evaluations of the urinary system on computed tomography and magnetic resonance imaging. Several neoplastic and non-neoplastic disorders and diseases including lipomatosis, angiomyolipoma and angiolipomatous proliferation, vascular lesions, lymphangiomatosis, Rosai–Dorfman disease, Erdheim–Chester disease, extramedullary hematopoiesis, IgG4-related disease, lymphoma, mesenchymal tumors, trauma, and Antopol–Goldman lesion may involve these areas. Differentiation of these benign or malignant pathologies among themselves and from primary renal pathologies is of utmost importance to expedite the triage of patients for correct treatment approach. In this article, we aim to increase the awareness of the imaging specialists to the typical and atypical imaging features of the entities affecting these areas.
Background. Amyand's hernia is rarely noted in children, and appendicitis caused by a foreign bod... more Background. Amyand's hernia is rarely noted in children, and appendicitis caused by a foreign body in Amyand's hernia is even rarer. Case. A 2-year-old girl presented with recurrent conglomerate lymph node enlargements and an abscess in the right groin existing for one year despite medical treatment. Direct radiography revealed a foreign body in the right inguinal region. Computed tomography showed a foreign body and soft tissue inflammation in the inguinal canal. Laparotomy was performed, and Amyand's hernia was diagnosed. A foreign body was found in the lumen of the appendix vermiformis causing perforated appendicitis. This case is presented because of its rarity and unusual clinical presentation. Conclusion. Amyand's hernia should be considered in paediatric cases with the history of recurrent inguinal abscesses.
106 alignant melanoma is a neoplasm that originates from melanocytes. The overall incidence of th... more 106 alignant melanoma is a neoplasm that originates from melanocytes. The overall incidence of this rare neoplasm has increased dramatically in recent years. Melanomas are serious and difficult to treat neoplasm and metastasis to liver, lung and brain can be seen with a poor survival rate.1 Recurrence of malignant melanoma after successful surgical treatment may not be seen for decades however it can recur even several years after the initial diagnosis with curative treatment.2
Sclerosing stromal tumor (SST) is a benign stromal tumor of the ovary. Preoperative diagnosis of ... more Sclerosing stromal tumor (SST) is a benign stromal tumor of the ovary. Preoperative diagnosis of this benign tumor mainly depends on imaging findings. Dynamic computed tomography (CT) and magnetic resonance imaging (MRI) show typical contrast enhancement of SST with peripheral enhancement in the early phase and centripetal progression in the delayed phases. We present the imaging findings of ultrasonography, ultrasound elastography, and dynamic MRI in the diagnosis of SST. Abdominal ultrasound elastography is a novel technique that depicts the stromal structure of SSTs by comparing the elasticity of the tumor and the myometrium using quantitative strain values.
A 50-year-old female patient presented to emergency department with severe epigastric pain. She h... more A 50-year-old female patient presented to emergency department with severe epigastric pain. She had pain for the last 4 days. Her history revealed that the patient had been diagnosed with osteosarcoma in the left femur 2 years ago and amputation of the leg above the lesion was performed. She also received adjuvant chemotherapy. During follow-up, a mass was identified in her esophagus in 2008 and biopsy revealed metastatic osteosarcoma. Upon admission to our department, laboratory examination was normal. Patient had severe dysphagia and mass related obstructed lumen of esophagus. After several unsuccessful esophagus dilatation attempts, a gastrostomy was opened in order to feed the patient. An abdominal computed tomography was performed after giving nonionic contrast material through the gastrostomy tube and intravenous contrast administration. There was a huge ossified mass in the mediastinum and epigastrium with invasion of the pleura and diaphragm (Fig. 1). Metastatic mass was encircling the aorta but not invading its wall (Fig. 2). The stomach was also compressed by the mass. The density measurement of this mass revealed 991 HU indicating calcification (Fig. 1), whereas the density measured over the intestinal loops was 324 HU. No esophageal perforation was present. Palliative treatment including chemotherapy and feeding via gastrostomy tube was administered to the patient. She died because of metastatic osteosarcoma 3 months after hospitalization.
Citations to scholarly items are building bricks for multidisciplinary science communication. Cit... more Citations to scholarly items are building bricks for multidisciplinary science communication. Citation analyses are currently influencing individual career advancement and ranking of academic and research institutions worldwide. This article overviews the involvement of scientific authors, reviewers, editors, publishers, indexers, and learned associations in the citing and referencing to preserve the integrity of science communication. Authors are responsible for thorough bibliographic searches to select relevant references for their articles, comprehend main points, and cite them in an ethical way. Reviewers and editors may perform additional searches and recommend missing essential references. Publishers, in turn, are in a position to instruct their authors over the citations and references, provide tools for validation of references, and open access to bibliographies. Publicly available reference lists bear important information about the novelty and relatedness of the scholarly items with the published literature. Few editorial associations have dealt with the issue of citations and properly managed references. As a prime example, the International Committee of Medical Journal Editors (ICMJE) issued in December 2014 an updated set of recommendations on the need for citing primary literature and avoiding unethical references, which are applicable to the global scientific community. With the exponential growth of literature and related references, it is critically important to define functions of all stakeholders of science communication in curbing the issue of irrational and unethical citations and thereby improve the quality and indexability of scholarly journals.
The use of radiological imaging in urological cancers is increasing with improvements in imaging ... more The use of radiological imaging in urological cancers is increasing with improvements in imaging technologies and implementation of these techniques to clinical scenarios. Ultrasonography, computed tomography, and magnetic resonance imaging have enormous potentials in the diagnosis, staging, and surveillance of urological cancers. Emerging imaging techniques enable morphologic assessment of urological cancers with high spatial and contrast resolution. Functional imaging techniques reveal microstructure of tumors which can be used in the diagnosis, prediction of prognosis, and assessment of response to treatment and surveillance of tumors. Biopsyless diagnosis may be possible in the future particularly for renal and prostate tumors. In this chapter, current status of urooncologic imaging will be reviewed.
Kidney neoplasms are common clinical disorders now being detected in even great-er numbers due to... more Kidney neoplasms are common clinical disorders now being detected in even great-er numbers due to the widespread use of cross-sectional imaging. Benign kidney neoplasms, once thought to be highly unusual, are being diagnosed in ever increas-ing numbers. In one series, 16.1 % of patients who underwent partial nephrectomy for a presumed solitary renal cell carcinoma turned out to have a benign diagnosis in the final pathological analysis (1). Recent developments on computed tomography (CT) and mag-netic resonance imaging (MRI) have limited value in differentiation between benign and malignant renal masses. Diffusion MRI studies yielded significantly different apparent dif-fusion coefficient (ADC) values between benign and malignant renal masses. These studies mostly evaluated the different ADC values between oncocytoma/angiomyolipoma and re-nal cell carcinomas (2). The role of ADC values in differentiation between uncommon be-nign renal masses and malignant renal masses has not been w...
Background: To explore the clinical significance of baseline volumetric body composition paramete... more Background: To explore the clinical significance of baseline volumetric body composition parameters evaluated with computerized tomography (CT) and their changes after 3-4 months from treatment initiation of targeted therapy in patients with metastatic renal cell carcinoma (mRCC). Method: This study included 108 Caucasian mRCC patients (Male/Female: 77/31) treated with targeted therapy. Volumetric body composition parameters including total adipose tissue index (TATI), subcutaneous adipose tissue index (SATI), visceral adipose tissue index (VATI) and skeletal muscle index (SMI) values were depicted from CT images at third lumbar vertebra level through volumetric measurement software. Kaplan-Meier method and the long test were used for estimation of progression free survival (PFS) and overall survival (OS). Univariate and multivariate analyses were done to determine the associations between clinic-pathologic variables including VBC and survival outcomes. Results: The median PFS and O...
Poster: "EuroSafe Imaging 2018 / ESI-0052 / Optimisation of CT protocols in abdominal emerge... more Poster: "EuroSafe Imaging 2018 / ESI-0052 / Optimisation of CT protocols in abdominal emergencies" by: "M. R. Onur, I. Idilman, E. Akpinar, M. N. Ozmen, D. Akata; Hacettepe University Faculty of Medicine Department of Radiology Ankara/TR"
Abdominal pain is one of the most common complaints of patients presenting to the emergency depar... more Abdominal pain is one of the most common complaints of patients presenting to the emergency department. Among the patients with abdominal pain, appendicitis is the most common surgical disorder. Appendicitis presenting with left lower quadrant pain may result in false-negative diagnosis. Left sided appendicitis occurs in association with situs inversus and intestinal malrotation. We describe a rare case of left sided appendicitis with situs inversus totalis. Key Words: Appendicitis, Situs inversus, Ultrasonography
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