... Ana Paula Noronha Barrére Rua Ivaí, 812, apt 21, Bairro Santa Maria 09560-570 São Caetano d... more ... Ana Paula Noronha Barrére Rua Ivaí, 812, apt 21, Bairro Santa Maria 09560-570 São Caetano do Sul SP Tel ... 7. Vasconcelos, RF; Albuquerque, VB; Costa, MLG Reflexões da clínica terapêutica ocupacional junto à criança com câncer na vigência ... São Paulo: Marina; 2003. ...
Page 1. Arq Bras Cardiol 2001; 77: 439-45. Leite e cols Síncope durante taquicardia ventricular s... more Page 1. Arq Bras Cardiol 2001; 77: 439-45. Leite e cols Síncope durante taquicardia ventricular sustentada 439 Universidade Federal de São Paulo Escola Paulista de Medicina Correspondência: Luiz Roberto Leite Setor ...
Introduction: Sarcopenia is a prevalent condition, and that is strongly associated with morbimort... more Introduction: Sarcopenia is a prevalent condition, and that is strongly associated with morbimortality outcomes. The optimal way to diagnose sarcopenia is currently a matter of debate. Despite evidence suggesting differences in body composition and physical performance of individuals from different regions, the diagnosis of sarcopenia in Brazil is still conducted using cutoff values established by international consensus. Therefore, the objective of this study was to establish cutoff values for appendicular muscle mass and muscle strength in a population of elderly outpatients with cardiovascular diseases from the city of São Paulo, using this data to compare populations with sarcopenia diagnosed in Brazil with individuals diagnosed using the European consensus values. Materials and Methods: This was a cross-sectional analysis including 502 older individuals from the SARCOS-Brazil study. All subjects underwent densitometry to assess muscle mass and measure strength using a manual dynamometer. The cutoff values for the SARCOS-Brazil criteria were obtained from the 25th percentile of each variable. Results and Discussion: There was no difference in the prevalence of muscle weakness using the two methods (180 patients, 35.9% of the sample). However, a difference was observed concerning low muscle mass. According to the European criteria, a total of 215 older individuals (42.8%) had low muscle mass and 123 (24.5%) according to the SARCOS-Brazil criteria. The prevalence of sarcopenia was 20.3% according to European criteria versus 13.7% according to the SARCOS-Brazil criteria. The kappa coefficient was 0.79. Conclusion: This study suggests that weakness and muscle mass can, in isolation, predict variables related to past vulnerability outcomes, as well as highlights the possibility of using regional cutoff values for the diagnosis of sarcopenia. Keywords: Sarcopenia; Aging; Muscle mass; Muscle strength
Communications In Statistics: Case Studies, Data Analysis And Applications, Sep 9, 2021
Abstract Longitudinal studies are best suited to describe the evolution of particular health cond... more Abstract Longitudinal studies are best suited to describe the evolution of particular health conditions over time. In this study, data on the occurrence and transition of cough among post-operative cardiac surgery patients was analyzed using semi-parametric regression models for recurrent events. Cough severity was recorded as no cough, mild cough and severe cough. Transition probability matrix was calculated for the various transitions and across different covariate categories. Also, mean first passage time (MFPT) was calculated using Markov principles and Monte-Carlo simulation. The Andersen-Gill (AG) and Prentice, Williams and Peterson (PWP) semi-parametric regression models were used to test the effect of covariates on the cough transition. Ninety percent of the patients developed cough on the first post-operative day. The probability of transitioning from no cough to severe cough was 8% but the probability of resolution was just 3%. The mean first passage time from no cough to severe cough was about 7.2 (95% CI 6.8–7.5) days and the resolution time was 13.7 (13.0–14.5) days. The MFPT varied widely across the covariate categories. The regression models did not reveal any major significant influences by the measured covariates and the models without covariates were not significantly different from the covariate models. Applying these statistical techniques can serve as effective tools to help medical decision makers to provide better, consistent, efficient and evidence-based healthcare services.
e15043 Background: Evidence suggests that obesity is biologically associated with the development... more e15043 Background: Evidence suggests that obesity is biologically associated with the development of prostate cancer (PCa) and may increase the risk of a more aggressive cancer. We investigated if ...
Introduction In older individuals with cardiovascular diseases, it has been challenging to diagno... more Introduction In older individuals with cardiovascular diseases, it has been challenging to diagnose osteoporosis due to aortic calcification and degenerative processes in the spine of older adults, especially in very old adults. Aim To assess whether the distal forearm BMD with the proximal femur BMD has greater sensitivity for the diagnosis of osteoporosis than the lumbar spine BMD with the proximal femur BMD. Methods We evaluated 515 older adults with cardiovascular disease from the SARCOS study and stratified them into under and over 80-year-old age groups and according to gender. Two diagnostic criteria were used to assess osteoporosis, SPF (lumbar spine and proximal femur BMD) and DFF (distal forearm and proximal femur BMD), which were compared with the multiple bone sites (MS) criteria (lumbar spine, distal radius, femoral neck, and total femur BMD). Results 43.9% were aged ≥80 years. Osteoporosis by SPF was diagnosed in 34% (n = 175), by DFF in 42.2% (n = 216), and by MS in 46.8% (n = 241). The characteristics of the three groups were similar. For every 100 older individuals with osteoporosis based on MS, 27 were not diagnosed by the SPF, and nine were not diagnosed by DFF (p = 0.001). The SPF did not diagnose osteoporosis in 23/100 in older adults aged <80 years, while DFF did not diagnose 16/100 (p.ns). In adults aged ≥80 years, the SPF did not identify osteoporosis in 31/100 older adults, while the DFF failed to identify it in only 5/100 (p < 0.001). In men and women aged ≥80 years, DFF showed higher sensitivity for the diagnosis of osteoporosis compared to the SPF criterion. Conclusion In the elderly population with cardiovascular disease evaluated in our study, the use of distal forearm BMD instead of lumbar spine BMD, associated with proximal femur BMD, showed higher sensitivity for the diagnosis of osteoporosis, regardless of gender, and especially among the very older adults.
... Ana Paula Noronha Barrére Rua Ivaí, 812, apt 21, Bairro Santa Maria 09560-570 São Caetano d... more ... Ana Paula Noronha Barrére Rua Ivaí, 812, apt 21, Bairro Santa Maria 09560-570 São Caetano do Sul SP Tel ... 7. Vasconcelos, RF; Albuquerque, VB; Costa, MLG Reflexões da clínica terapêutica ocupacional junto à criança com câncer na vigência ... São Paulo: Marina; 2003. ...
Page 1. Arq Bras Cardiol 2001; 77: 439-45. Leite e cols Síncope durante taquicardia ventricular s... more Page 1. Arq Bras Cardiol 2001; 77: 439-45. Leite e cols Síncope durante taquicardia ventricular sustentada 439 Universidade Federal de São Paulo Escola Paulista de Medicina Correspondência: Luiz Roberto Leite Setor ...
Introduction: Sarcopenia is a prevalent condition, and that is strongly associated with morbimort... more Introduction: Sarcopenia is a prevalent condition, and that is strongly associated with morbimortality outcomes. The optimal way to diagnose sarcopenia is currently a matter of debate. Despite evidence suggesting differences in body composition and physical performance of individuals from different regions, the diagnosis of sarcopenia in Brazil is still conducted using cutoff values established by international consensus. Therefore, the objective of this study was to establish cutoff values for appendicular muscle mass and muscle strength in a population of elderly outpatients with cardiovascular diseases from the city of São Paulo, using this data to compare populations with sarcopenia diagnosed in Brazil with individuals diagnosed using the European consensus values. Materials and Methods: This was a cross-sectional analysis including 502 older individuals from the SARCOS-Brazil study. All subjects underwent densitometry to assess muscle mass and measure strength using a manual dynamometer. The cutoff values for the SARCOS-Brazil criteria were obtained from the 25th percentile of each variable. Results and Discussion: There was no difference in the prevalence of muscle weakness using the two methods (180 patients, 35.9% of the sample). However, a difference was observed concerning low muscle mass. According to the European criteria, a total of 215 older individuals (42.8%) had low muscle mass and 123 (24.5%) according to the SARCOS-Brazil criteria. The prevalence of sarcopenia was 20.3% according to European criteria versus 13.7% according to the SARCOS-Brazil criteria. The kappa coefficient was 0.79. Conclusion: This study suggests that weakness and muscle mass can, in isolation, predict variables related to past vulnerability outcomes, as well as highlights the possibility of using regional cutoff values for the diagnosis of sarcopenia. Keywords: Sarcopenia; Aging; Muscle mass; Muscle strength
Communications In Statistics: Case Studies, Data Analysis And Applications, Sep 9, 2021
Abstract Longitudinal studies are best suited to describe the evolution of particular health cond... more Abstract Longitudinal studies are best suited to describe the evolution of particular health conditions over time. In this study, data on the occurrence and transition of cough among post-operative cardiac surgery patients was analyzed using semi-parametric regression models for recurrent events. Cough severity was recorded as no cough, mild cough and severe cough. Transition probability matrix was calculated for the various transitions and across different covariate categories. Also, mean first passage time (MFPT) was calculated using Markov principles and Monte-Carlo simulation. The Andersen-Gill (AG) and Prentice, Williams and Peterson (PWP) semi-parametric regression models were used to test the effect of covariates on the cough transition. Ninety percent of the patients developed cough on the first post-operative day. The probability of transitioning from no cough to severe cough was 8% but the probability of resolution was just 3%. The mean first passage time from no cough to severe cough was about 7.2 (95% CI 6.8–7.5) days and the resolution time was 13.7 (13.0–14.5) days. The MFPT varied widely across the covariate categories. The regression models did not reveal any major significant influences by the measured covariates and the models without covariates were not significantly different from the covariate models. Applying these statistical techniques can serve as effective tools to help medical decision makers to provide better, consistent, efficient and evidence-based healthcare services.
e15043 Background: Evidence suggests that obesity is biologically associated with the development... more e15043 Background: Evidence suggests that obesity is biologically associated with the development of prostate cancer (PCa) and may increase the risk of a more aggressive cancer. We investigated if ...
Introduction In older individuals with cardiovascular diseases, it has been challenging to diagno... more Introduction In older individuals with cardiovascular diseases, it has been challenging to diagnose osteoporosis due to aortic calcification and degenerative processes in the spine of older adults, especially in very old adults. Aim To assess whether the distal forearm BMD with the proximal femur BMD has greater sensitivity for the diagnosis of osteoporosis than the lumbar spine BMD with the proximal femur BMD. Methods We evaluated 515 older adults with cardiovascular disease from the SARCOS study and stratified them into under and over 80-year-old age groups and according to gender. Two diagnostic criteria were used to assess osteoporosis, SPF (lumbar spine and proximal femur BMD) and DFF (distal forearm and proximal femur BMD), which were compared with the multiple bone sites (MS) criteria (lumbar spine, distal radius, femoral neck, and total femur BMD). Results 43.9% were aged ≥80 years. Osteoporosis by SPF was diagnosed in 34% (n = 175), by DFF in 42.2% (n = 216), and by MS in 46.8% (n = 241). The characteristics of the three groups were similar. For every 100 older individuals with osteoporosis based on MS, 27 were not diagnosed by the SPF, and nine were not diagnosed by DFF (p = 0.001). The SPF did not diagnose osteoporosis in 23/100 in older adults aged <80 years, while DFF did not diagnose 16/100 (p.ns). In adults aged ≥80 years, the SPF did not identify osteoporosis in 31/100 older adults, while the DFF failed to identify it in only 5/100 (p < 0.001). In men and women aged ≥80 years, DFF showed higher sensitivity for the diagnosis of osteoporosis compared to the SPF criterion. Conclusion In the elderly population with cardiovascular disease evaluated in our study, the use of distal forearm BMD instead of lumbar spine BMD, associated with proximal femur BMD, showed higher sensitivity for the diagnosis of osteoporosis, regardless of gender, and especially among the very older adults.
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