Background: The challenge of substance use among youth continues to be a highly concerning public... more Background: The challenge of substance use among youth continues to be a highly concerning public health issue across the globe. The notion that parenting lifestyles and family-based intervention can help in the prevention of adolescent substance use have received robust attention from policy makers, researchers’ clinicians and general public, nonetheless, there is scarcity of high quality evidence to support these concepts. Objective: To review available literature which assessed the effects of parenting styles and family-based interventions on the prevention of adolescent substance use. Methods: A scoping review of literature to identify studies published in English between 2012 and 2022 was conducted searching Scopus, MEDLINE, PsychInfo, and CINAHL databases focused on effects of parenting styles and family-based interventions in the prevention of adolescent substance use. Keywords of family-based intervention strategies and possible outcomes of parenting styles on youth substanc...
Objectives: To investigate heart size on chest X-ray via cardiothoracic ratio, and to correlate i... more Objectives: To investigate heart size on chest X-ray via cardiothoracic ratio, and to correlate it with echocardiographic measurements. Method: The comparative analytical, cross-sectional study was conducted at the Pakistan Navy Station Shifa Hospital, Karachi, between January 2021 and July 2021. The radiological parameters were measured on chest X-rays posterior-anterior view, and the echocardiographic parameters were measured using 2-dimensional transthoracic echocardiography. The absence or presence of cardiomegaly on both imaging modalities was modelled as a binary categorical variable and compared. Data was analysed using SPSS 23. Results: Of the 79 participants, 44(55.7%) were males and 35(44.3%) were females. The mean age of the sample was 52.71±14.54 years. There were 28(35.44%) enlarged hearts on chest X-ray and 46(58.22%) on echocardiography. The sensitivity and specificity of chest X-ray were 54.35% and 90.90%, respectively. The positive and negative predictive values we...
S. Ceylan2, S. C. Stähler2, D. Giardini2, M. Böse, M. van Driel2, A. Horleston3, T. Kawamura4 , S... more S. Ceylan2, S. C. Stähler2, D. Giardini2, M. Böse, M. van Driel2, A. Horleston3, T. Kawamura4 , S. Kedar5 , A. Khan2, F. Euchner1, B. Banerdt5 , P. Lognonné4 . 1Swiss Seismological Service, ETH Zürich, Sonneggstr. 5, 8092 Zürich, Switzerland. Institute of Geophysics, ETH Zürich, Sonneggstr. 5, 8092 Zürich, Switzerland, 3University of Bristol, Bristol, United Kingdom, 4 Institut de Physique du Globe de Paris, Paris, France, 5 Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, United States,
Malignant Pleural Mesothelioma (MPM) is a rare pleural malignancy, with a vague presentation comp... more Malignant Pleural Mesothelioma (MPM) is a rare pleural malignancy, with a vague presentation complicated by a decades-long latency period between environmental exposure and clinical manifestations. Spontaneous hydro-pneumothorax is a rare presentation of MPM, most often requiring invasive tissue biopsy to confirm the etiologic diagnosis. We present the case of 79-year-old male smoker with no documented history of asbestos exposure, who was found to have MPM after presenting with dyspnea and subsequently found to have recurrent hydro-pneumothorax. On Literature review of the limited documented cases of MPM with hydro-pneumothorax, we found an exclusively male population with a significant smoking history, a marked right sided pathology predominance, and a generally poor prognosis. While this corresponds with the examined case, and suggests that the presence of hydro-pneumothorax implies a high-grade tumor and significant tissue invasion, and therefore poor prognosis similar to that o...
The science of formulation involving cosmetic ingredients has always been a challenge since the r... more The science of formulation involving cosmetic ingredients has always been a challenge since the release of active components greatly depends upon the carrier system involved and the selectivity of skin barrier. The principle obstacle of the skin resides in the epidermis and it's hard for many active components to cross it. The formulation related factors like size of particles, viscosity and lipophilicity of the components also play an important role in permeation of the dermal composition. Though widely used; conventional creams and gels still struggle in terms of success. This work focuses on nano based formulation strategies for successful delivery of cosmetic agents. Novel strategies like nanoemulsion, nanogels, liposomes, aquasomes, niosomes, dendrimers and fullerenes have paved way for successful delivery of dermal formulations to desire depths in the skin.
Background: The challenge of substance use among youth continues to be a highly concerning public... more Background: The challenge of substance use among youth continues to be a highly concerning public health issue across the globe. The notion that parenting lifestyles and family-based intervention can help in the prevention of adolescent substance use have received robust attention from policy makers, researchers’ clinicians and general public, nonetheless, there is scarcity of high quality evidence to support these concepts. Objective: To review available literature which assessed the effects of parenting styles and family-based interventions on the prevention of adolescent substance use. Methods: A scoping review of literature to identify studies published in English between 2012 and 2022 was conducted searching Scopus, MEDLINE, PsychInfo, and CINAHL databases focused on effects of parenting styles and family-based interventions in the prevention of adolescent substance use. Keywords of family-based intervention strategies and possible outcomes of parenting styles on youth substanc...
Objectives: To investigate heart size on chest X-ray via cardiothoracic ratio, and to correlate i... more Objectives: To investigate heart size on chest X-ray via cardiothoracic ratio, and to correlate it with echocardiographic measurements. Method: The comparative analytical, cross-sectional study was conducted at the Pakistan Navy Station Shifa Hospital, Karachi, between January 2021 and July 2021. The radiological parameters were measured on chest X-rays posterior-anterior view, and the echocardiographic parameters were measured using 2-dimensional transthoracic echocardiography. The absence or presence of cardiomegaly on both imaging modalities was modelled as a binary categorical variable and compared. Data was analysed using SPSS 23. Results: Of the 79 participants, 44(55.7%) were males and 35(44.3%) were females. The mean age of the sample was 52.71±14.54 years. There were 28(35.44%) enlarged hearts on chest X-ray and 46(58.22%) on echocardiography. The sensitivity and specificity of chest X-ray were 54.35% and 90.90%, respectively. The positive and negative predictive values we...
S. Ceylan2, S. C. Stähler2, D. Giardini2, M. Böse, M. van Driel2, A. Horleston3, T. Kawamura4 , S... more S. Ceylan2, S. C. Stähler2, D. Giardini2, M. Böse, M. van Driel2, A. Horleston3, T. Kawamura4 , S. Kedar5 , A. Khan2, F. Euchner1, B. Banerdt5 , P. Lognonné4 . 1Swiss Seismological Service, ETH Zürich, Sonneggstr. 5, 8092 Zürich, Switzerland. Institute of Geophysics, ETH Zürich, Sonneggstr. 5, 8092 Zürich, Switzerland, 3University of Bristol, Bristol, United Kingdom, 4 Institut de Physique du Globe de Paris, Paris, France, 5 Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, United States,
Malignant Pleural Mesothelioma (MPM) is a rare pleural malignancy, with a vague presentation comp... more Malignant Pleural Mesothelioma (MPM) is a rare pleural malignancy, with a vague presentation complicated by a decades-long latency period between environmental exposure and clinical manifestations. Spontaneous hydro-pneumothorax is a rare presentation of MPM, most often requiring invasive tissue biopsy to confirm the etiologic diagnosis. We present the case of 79-year-old male smoker with no documented history of asbestos exposure, who was found to have MPM after presenting with dyspnea and subsequently found to have recurrent hydro-pneumothorax. On Literature review of the limited documented cases of MPM with hydro-pneumothorax, we found an exclusively male population with a significant smoking history, a marked right sided pathology predominance, and a generally poor prognosis. While this corresponds with the examined case, and suggests that the presence of hydro-pneumothorax implies a high-grade tumor and significant tissue invasion, and therefore poor prognosis similar to that o...
The science of formulation involving cosmetic ingredients has always been a challenge since the r... more The science of formulation involving cosmetic ingredients has always been a challenge since the release of active components greatly depends upon the carrier system involved and the selectivity of skin barrier. The principle obstacle of the skin resides in the epidermis and it's hard for many active components to cross it. The formulation related factors like size of particles, viscosity and lipophilicity of the components also play an important role in permeation of the dermal composition. Though widely used; conventional creams and gels still struggle in terms of success. This work focuses on nano based formulation strategies for successful delivery of cosmetic agents. Novel strategies like nanoemulsion, nanogels, liposomes, aquasomes, niosomes, dendrimers and fullerenes have paved way for successful delivery of dermal formulations to desire depths in the skin.
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Papers by Ahmed Ali Khan