We aim to work on the global distribution modeling of novae in M31 and to investigate the open qu... more We aim to work on the global distribution modeling of novae in M31 and to investigate the open question of a possible bimodal (disk/bulge) population split. To support this project, we require optical observations (spectra as well as photometry) to classify the novae included in our study. Follow-up with X-ray observations using Swift, XMM-Newton, and Chandra will be used to correlate their spectral type, and decline rate of the light curve with its corresponding X-ray phase. The spectral classification of novae is essential to our project in interpreting the correlation between nova type, location within M31 (bulge/disk), temporal decay behavior in the optical regime, and temporal/spectral behavior in the X-ray regime (Super-Soft Source phase, or otherwise). We detect approximately 2 novae per month in M31. Typical peak brightnesses are 15 mag, but drop to 20 mag within a few weeks. Because of this rapid decline, we request Target of Opportunity follow-up spectroscopy for bright post-discovery novae visible from KPNO.
In the present study, an attempt was made to study the acute and sub-acute toxicity profile of G3... more In the present study, an attempt was made to study the acute and sub-acute toxicity profile of G3-COOH Poly (propyl ether imine) [PETIM] dendrimer and its use as a carrier for sustained delivery of model drug ketoprofen. Drug-dendrimer complex was prepared and characterized by FTIR, solubility and in vitro drug release study. PETIM dendrimer was found to have significantly less toxicity in A541 cells compared to Poly amido amine (PAMAM) dendrimer. Further, acute and 28 days sub-acute toxicity measurement in mice showed no mortality, hematological, biochemical or histopathological changes up to 80 mg/kg dose of PETIM dendrimer. The results of study demonstrated that G3-COOH PETIM dendrimer can be used as a safe and efficient vehicle for sustained drug delivery.
We aim to work on the global distribution modeling of novae in M31 and to investigate the open qu... more We aim to work on the global distribution modeling of novae in M31 and to investigate the open question of a possible bimodal (disk/bulge) population split. To support this project, we require optical observations (spectra as well as photometry) to classify the novae included in our study. Follow-up with X-ray observations using Swift, XMM-Newton, and Chandra will be used to correlate their spectral type, and decline rate of the light curve with its corresponding X-ray phase. The spectral classification of novae is essential to our project in interpreting the correlation between nova type, location within M31 (bulge/disk), temporal decay behavior in the optical regime, and temporal/spectral behavior in the X-ray regime (Super-Soft Source phase, or otherwise). We detect approximately 2 novae per month in M31. Typical peak brightnesses are 15 mag, but drop to 20 mag within a few weeks. Because of this rapid decline, we request Target of Opportunity follow-up spectroscopy for bright post-discovery novae visible from KPNO.
In the present study, an attempt was made to study the acute and sub-acute toxicity profile of G3... more In the present study, an attempt was made to study the acute and sub-acute toxicity profile of G3-COOH Poly (propyl ether imine) [PETIM] dendrimer and its use as a carrier for sustained delivery of model drug ketoprofen. Drug-dendrimer complex was prepared and characterized by FTIR, solubility and in vitro drug release study. PETIM dendrimer was found to have significantly less toxicity in A541 cells compared to Poly amido amine (PAMAM) dendrimer. Further, acute and 28 days sub-acute toxicity measurement in mice showed no mortality, hematological, biochemical or histopathological changes up to 80 mg/kg dose of PETIM dendrimer. The results of study demonstrated that G3-COOH PETIM dendrimer can be used as a safe and efficient vehicle for sustained drug delivery.
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Papers by Amanpreet Kaur