The aerial parts of Salvia cinnabarina afforded two undescribed labdane diterpenoids 1 and 2 (mal... more The aerial parts of Salvia cinnabarina afforded two undescribed labdane diterpenoids 1 and 2 (malonylcommunol and 6β-hydroxy-trans-communic acid) along with two known labdane diterpenoids, trans-communic acid (3) and trans-communol (4). Additionally, seven known metabolites were also isolated; two isopimarane diterpenoids 5 and 6, two sesquiterpenoids identified as β-eudesmol (7) and cryptomeridiol (8), and three aromatic compounds identified as phthalic acid (9), a mixture of tyrosol fatty acid esters (10) and the flavone salvigenine (11). While compounds compounds 1–3 showed significant inhibition of yeast α-glucosidase, compounds 2, 3 and 7 had no anti-inflammatory activity in the edema model induced by TPA. This paper is not only the first report on a wild population of Salvia cinnabarina, but also of the presence of labdane-type diterpenoids in a Mexican Salvia sp.
EN EL DEPARTAMENTO DE PRODUCTOS NATURALES DEL INSTITUTO DE QUIMICA SE HAN AISLADO Y CARACTERIZADO... more EN EL DEPARTAMENTO DE PRODUCTOS NATURALES DEL INSTITUTO DE QUIMICA SE HAN AISLADO Y CARACTERIZADO APROXIMADAMENTE TRES MIL 500 SUSTANCIAS QUIMICAS PERTENECIENTES A DIFERENTES FAMILIAS COMO FLAVONOIDES, ALCALOIDES Y TERPENOIDES ENTRE OTRAS. ACTUALMENTE SE DESARROLLA UNA BASE DE DATOS CON LOS RESULTADOS GENERADOS POR SUS INVESTIGADORES A TRAVES DE LA UNIDAD DE INFORM TICA DEL PROPIO INSTITUTO EN COLABORACION CON EL SISTEMA DE INFORM TICA PARA LA BIODIVERSIDAD Y EL AMBIENTE.
The known clerodane diterpenes salviarin 1 and 6β-hydroxy-7,8-dehydrobacchatricunactin 2, were is... more The known clerodane diterpenes salviarin 1 and 6β-hydroxy-7,8-dehydrobacchatricunactin 2, were isolated from Salvia rhyacophila together with five new clerodane diterpenoids 3-6 and 12. The structures of diterpenes 3-6 were established on spectral evidence and chemical transformations. Rhyacophiline is an aromatic seco-clerodane diterpenoid whose structure 12 was established by spectral means and X-ray diffraction analysis.From the aerial parts of Salvia rhyacophila seven clerodane diterpenoids were isolated. Rhyacophiline (12), an aromatic seco-clero-danediterpenoid was isolated and its structure established by spectral means and X-ray diffraction analysis.
Rhizobia are able to convert dinitrogen into biologically available forms of nitrogen through the... more Rhizobia are able to convert dinitrogen into biologically available forms of nitrogen through their symbiotic association with leguminous plants. This results in plant growth promotion, and also in conferring host resistance to different types of stress. These bacteria can interact with other organisms and survive in a wide range of environments, such as soil, rhizosphere, and inside roots. As most of these processes are molecularly mediated, the aim of this research was to identify and quantify the exo-metabolites produced by Rhizobium etli CFN42, Rhizobium leucaenae CFN299, Rhizobium tropici CIAT899, Rhizobium phaseoli Ch24-10, and Sinorhizobium americanum CFNEI156, by nuclear magnetic resonance (NMR). Bacteria were grown in free-living cultures using minimal medium containing sucrose and glutamate. Interestingly, we found that even when these bacteria belong to the same family (Rhizobiaceae) and all form nitrogen-fixing nodules on Phaseolus vulgaris roots, they exhibited differen...
Detailed literature inspections regarding the diterpenoids icetexone (1) and conacytone (3) revea... more Detailed literature inspections regarding the diterpenoids icetexone (1) and conacytone (3) reveal that the absolute configuration (AC) of these natural occurring compounds is not rigorously proven, despite they were originally isolated in 1976. This task is now completed by single-crystal X-ray diffraction Flack and Hooft parameters determination after processing data collected with Cu Kα graphite monochromated radiation. The AC of both compounds is further determined by vibrational circular dichroism measurements performed on icetexone acetate (2) and conacytone triacetate (4) since the solubility of 1 and 3 is limited. Comparison of the substituent chemical shifts (SCS) induced by acetylation of 1 and 3 to afford 2 and 4, respectively, reveals that in the case of icetexone, all six SCS values of the quinone ring are in excellent agreement with the expected values, while in the case of conacytone, three agree and three do not agree due to the presence of additional acetates near t...
Some years ago, a method for creating carboncarbon bonds through acyl radicals, was reported by ... more Some years ago, a method for creating carboncarbon bonds through acyl radicals, was reported by Pattenden et al. [1]. According to this procedure, a refluxing solution of an acyl salophencobalt(III) compound (1) in CH2Cl2 was irradiated with a sun lamp in the ...
The aqueous extract of the leaves of Ageratina cylindrica afforded six new ent-kaurenoic acid gly... more The aqueous extract of the leaves of Ageratina cylindrica afforded six new ent-kaurenoic acid glycosides together with the known diterpenoid paniculoside V, the flavonoid astragalin, chlorogenic acid, and l-chiro-inositol. The structures were elucidated mainly by NMR and MS methods, and the absolute configuration was established by vibrational circular dichroism spectroscopy. The new compounds showed moderate antiprotozoal activity against Entamoeba histolytica and Giardia lamblia trophozoites.
Acta Crystallographica Section C Crystal Structure Communications, 1994
ABSTRACT The whole molecule of (7R,8S,9R)-5,6-seco-neo-clerodane-1,3,5(10),13(16),14-pentaene-12-... more ABSTRACT The whole molecule of (7R,8S,9R)-5,6-seco-neo-clerodane-1,3,5(10),13(16),14-pentaene-12-oxo-15,16-epoxy-18,19;20(7)-diolide, C20H18O6, adopts a T-shaped conformation. The methyl groups on the gamma-lactone ring are related synclinally and the crystal packing is entirely the result of van der Waals forces.
ABSTRACT ChemInform is a weekly Abstracting Service, delivering concise information at a glance t... more ABSTRACT ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chapter Twelve NEO-CLERODANE DITERPENOIDS FROM AMERICAN SALVIA SPECIES Lydia Rodriguez-Hahn, Bald... more Chapter Twelve NEO-CLERODANE DITERPENOIDS FROM AMERICAN SALVIA SPECIES Lydia Rodriguez-Hahn, Baldomero Esquivel, and Jorge Cardenas Instituto de Quimica de la Universidad Nacional Autonoma de Mexico Cd. Universitaria, Circuito Exterior Coyoacan 045l0 ...
... BALDOMERO ESQUIVEL, JORGE CARDENAS, ALFREDO TOSCANO, MANUEL SORIANO-GARCIA and LYDIA RODRIGUE... more ... BALDOMERO ESQUIVEL, JORGE CARDENAS, ALFREDO TOSCANO, MANUEL SORIANO-GARCIA and LYDIA RODRIGUEZ-HAHN.* Institute de Quimica, Universidad ... UV and IR spectra were determined on Nicolet FT 5X and Perkin Elmer 552 spectrometers, respectively. ...
The aerial parts of Salvia cinnabarina afforded two undescribed labdane diterpenoids 1 and 2 (mal... more The aerial parts of Salvia cinnabarina afforded two undescribed labdane diterpenoids 1 and 2 (malonylcommunol and 6β-hydroxy-trans-communic acid) along with two known labdane diterpenoids, trans-communic acid (3) and trans-communol (4). Additionally, seven known metabolites were also isolated; two isopimarane diterpenoids 5 and 6, two sesquiterpenoids identified as β-eudesmol (7) and cryptomeridiol (8), and three aromatic compounds identified as phthalic acid (9), a mixture of tyrosol fatty acid esters (10) and the flavone salvigenine (11). While compounds compounds 1–3 showed significant inhibition of yeast α-glucosidase, compounds 2, 3 and 7 had no anti-inflammatory activity in the edema model induced by TPA. This paper is not only the first report on a wild population of Salvia cinnabarina, but also of the presence of labdane-type diterpenoids in a Mexican Salvia sp.
EN EL DEPARTAMENTO DE PRODUCTOS NATURALES DEL INSTITUTO DE QUIMICA SE HAN AISLADO Y CARACTERIZADO... more EN EL DEPARTAMENTO DE PRODUCTOS NATURALES DEL INSTITUTO DE QUIMICA SE HAN AISLADO Y CARACTERIZADO APROXIMADAMENTE TRES MIL 500 SUSTANCIAS QUIMICAS PERTENECIENTES A DIFERENTES FAMILIAS COMO FLAVONOIDES, ALCALOIDES Y TERPENOIDES ENTRE OTRAS. ACTUALMENTE SE DESARROLLA UNA BASE DE DATOS CON LOS RESULTADOS GENERADOS POR SUS INVESTIGADORES A TRAVES DE LA UNIDAD DE INFORM TICA DEL PROPIO INSTITUTO EN COLABORACION CON EL SISTEMA DE INFORM TICA PARA LA BIODIVERSIDAD Y EL AMBIENTE.
The known clerodane diterpenes salviarin 1 and 6β-hydroxy-7,8-dehydrobacchatricunactin 2, were is... more The known clerodane diterpenes salviarin 1 and 6β-hydroxy-7,8-dehydrobacchatricunactin 2, were isolated from Salvia rhyacophila together with five new clerodane diterpenoids 3-6 and 12. The structures of diterpenes 3-6 were established on spectral evidence and chemical transformations. Rhyacophiline is an aromatic seco-clerodane diterpenoid whose structure 12 was established by spectral means and X-ray diffraction analysis.From the aerial parts of Salvia rhyacophila seven clerodane diterpenoids were isolated. Rhyacophiline (12), an aromatic seco-clero-danediterpenoid was isolated and its structure established by spectral means and X-ray diffraction analysis.
Rhizobia are able to convert dinitrogen into biologically available forms of nitrogen through the... more Rhizobia are able to convert dinitrogen into biologically available forms of nitrogen through their symbiotic association with leguminous plants. This results in plant growth promotion, and also in conferring host resistance to different types of stress. These bacteria can interact with other organisms and survive in a wide range of environments, such as soil, rhizosphere, and inside roots. As most of these processes are molecularly mediated, the aim of this research was to identify and quantify the exo-metabolites produced by Rhizobium etli CFN42, Rhizobium leucaenae CFN299, Rhizobium tropici CIAT899, Rhizobium phaseoli Ch24-10, and Sinorhizobium americanum CFNEI156, by nuclear magnetic resonance (NMR). Bacteria were grown in free-living cultures using minimal medium containing sucrose and glutamate. Interestingly, we found that even when these bacteria belong to the same family (Rhizobiaceae) and all form nitrogen-fixing nodules on Phaseolus vulgaris roots, they exhibited differen...
Detailed literature inspections regarding the diterpenoids icetexone (1) and conacytone (3) revea... more Detailed literature inspections regarding the diterpenoids icetexone (1) and conacytone (3) reveal that the absolute configuration (AC) of these natural occurring compounds is not rigorously proven, despite they were originally isolated in 1976. This task is now completed by single-crystal X-ray diffraction Flack and Hooft parameters determination after processing data collected with Cu Kα graphite monochromated radiation. The AC of both compounds is further determined by vibrational circular dichroism measurements performed on icetexone acetate (2) and conacytone triacetate (4) since the solubility of 1 and 3 is limited. Comparison of the substituent chemical shifts (SCS) induced by acetylation of 1 and 3 to afford 2 and 4, respectively, reveals that in the case of icetexone, all six SCS values of the quinone ring are in excellent agreement with the expected values, while in the case of conacytone, three agree and three do not agree due to the presence of additional acetates near t...
Some years ago, a method for creating carboncarbon bonds through acyl radicals, was reported by ... more Some years ago, a method for creating carboncarbon bonds through acyl radicals, was reported by Pattenden et al. [1]. According to this procedure, a refluxing solution of an acyl salophencobalt(III) compound (1) in CH2Cl2 was irradiated with a sun lamp in the ...
The aqueous extract of the leaves of Ageratina cylindrica afforded six new ent-kaurenoic acid gly... more The aqueous extract of the leaves of Ageratina cylindrica afforded six new ent-kaurenoic acid glycosides together with the known diterpenoid paniculoside V, the flavonoid astragalin, chlorogenic acid, and l-chiro-inositol. The structures were elucidated mainly by NMR and MS methods, and the absolute configuration was established by vibrational circular dichroism spectroscopy. The new compounds showed moderate antiprotozoal activity against Entamoeba histolytica and Giardia lamblia trophozoites.
Acta Crystallographica Section C Crystal Structure Communications, 1994
ABSTRACT The whole molecule of (7R,8S,9R)-5,6-seco-neo-clerodane-1,3,5(10),13(16),14-pentaene-12-... more ABSTRACT The whole molecule of (7R,8S,9R)-5,6-seco-neo-clerodane-1,3,5(10),13(16),14-pentaene-12-oxo-15,16-epoxy-18,19;20(7)-diolide, C20H18O6, adopts a T-shaped conformation. The methyl groups on the gamma-lactone ring are related synclinally and the crystal packing is entirely the result of van der Waals forces.
ABSTRACT ChemInform is a weekly Abstracting Service, delivering concise information at a glance t... more ABSTRACT ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chapter Twelve NEO-CLERODANE DITERPENOIDS FROM AMERICAN SALVIA SPECIES Lydia Rodriguez-Hahn, Bald... more Chapter Twelve NEO-CLERODANE DITERPENOIDS FROM AMERICAN SALVIA SPECIES Lydia Rodriguez-Hahn, Baldomero Esquivel, and Jorge Cardenas Instituto de Quimica de la Universidad Nacional Autonoma de Mexico Cd. Universitaria, Circuito Exterior Coyoacan 045l0 ...
... BALDOMERO ESQUIVEL, JORGE CARDENAS, ALFREDO TOSCANO, MANUEL SORIANO-GARCIA and LYDIA RODRIGUE... more ... BALDOMERO ESQUIVEL, JORGE CARDENAS, ALFREDO TOSCANO, MANUEL SORIANO-GARCIA and LYDIA RODRIGUEZ-HAHN.* Institute de Quimica, Universidad ... UV and IR spectra were determined on Nicolet FT 5X and Perkin Elmer 552 spectrometers, respectively. ...
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