PURPOSE To evaluate the effect of population screening on low vision and blindness from open-angl... more PURPOSE To evaluate the effect of population screening on low vision and blindness from open-angle glaucoma. DESIGN Retrospective cohort study. STUDY POPULATION A very large population based screening for glaucoma was conducted in Malmö, Sweden, from 1992 to 1997. A total of 42 497 subjects were invited, of which 32 918 were screened and 9579 non-responders, i.e. did not participate. METHODS The records of glaucoma patients who had visited the Department of Ophthalmology at Malmö University Hospital, from Jan 1, 1987, to Dec 31, 2017, were reviewed. Patients diagnosed at or after the screening were assessed for moderate or severe vision impairment, which we call low vision, or blindness by the WHO definition. We corrected for selection bias by creating a group of potential screening participants from a comparison group of clinical patients. MAIN OUTCOME MEASURE Risk ratio of the cumulative incidence for bilateral low vision or blindness caused by glaucoma in screened patients compared with the potential participants. RESULTS The cumulative incidence of blindness was 0.17% in the screened population versus 0.32% among the potential participants; and for low vision 0.25% versus 0.53%. The risk ratio (95% CI) between the two was 0.52 (0.32-0.84) for blindness and 0.46 (0.31-0.68) for low vision. There were no differences in the proportion of potential confounders between the comparison group and the non-responders. CONCLUSIONS Our results suggest that population screening may reduce bilateral low vision and blindness from glaucoma by about 50%.
PURPOSE. To compare the performance of neural networks for perimetric glaucoma diagnosis when usi... more PURPOSE. To compare the performance of neural networks for perimetric glaucoma diagnosis when using different types of data inputs: numerical threshold sensitivities, Statpac Total Deviation and Pattern Deviation, and probability scores based on Total and Pattern Deviation probability maps (Carl Zeiss
All in-text references underlined in blue are linked to publications on ResearchGate, letting you... more All in-text references underlined in blue are linked to publications on ResearchGate, letting you access and read them immediately.
One eye per patient was included in the analysis. If both eyes had glaucoma one was randomly sele... more One eye per patient was included in the analysis. If both eyes had glaucoma one was randomly selected. We recorded the extent of visual field loss (as Mean Deviation) and visual acuity (VA) at the time of diagnosis and at the last visit. Beside, we calculated the widest diameter of the remaining central visual field (Figure 4). Low vision and blindness were defined according to WHO criteria, and the major reason for either was noted. The risk for blindness from glaucoma was analyzed by cumulative incidence calculation.
PURPOSE To evaluate the effect of population screening on low vision and blindness from open-angl... more PURPOSE To evaluate the effect of population screening on low vision and blindness from open-angle glaucoma. DESIGN Retrospective cohort study. STUDY POPULATION A very large population based screening for glaucoma was conducted in Malmö, Sweden, from 1992 to 1997. A total of 42 497 subjects were invited, of which 32 918 were screened and 9579 non-responders, i.e. did not participate. METHODS The records of glaucoma patients who had visited the Department of Ophthalmology at Malmö University Hospital, from Jan 1, 1987, to Dec 31, 2017, were reviewed. Patients diagnosed at or after the screening were assessed for moderate or severe vision impairment, which we call low vision, or blindness by the WHO definition. We corrected for selection bias by creating a group of potential screening participants from a comparison group of clinical patients. MAIN OUTCOME MEASURE Risk ratio of the cumulative incidence for bilateral low vision or blindness caused by glaucoma in screened patients compared with the potential participants. RESULTS The cumulative incidence of blindness was 0.17% in the screened population versus 0.32% among the potential participants; and for low vision 0.25% versus 0.53%. The risk ratio (95% CI) between the two was 0.52 (0.32-0.84) for blindness and 0.46 (0.31-0.68) for low vision. There were no differences in the proportion of potential confounders between the comparison group and the non-responders. CONCLUSIONS Our results suggest that population screening may reduce bilateral low vision and blindness from glaucoma by about 50%.
PURPOSE. To compare the performance of neural networks for perimetric glaucoma diagnosis when usi... more PURPOSE. To compare the performance of neural networks for perimetric glaucoma diagnosis when using different types of data inputs: numerical threshold sensitivities, Statpac Total Deviation and Pattern Deviation, and probability scores based on Total and Pattern Deviation probability maps (Carl Zeiss
All in-text references underlined in blue are linked to publications on ResearchGate, letting you... more All in-text references underlined in blue are linked to publications on ResearchGate, letting you access and read them immediately.
One eye per patient was included in the analysis. If both eyes had glaucoma one was randomly sele... more One eye per patient was included in the analysis. If both eyes had glaucoma one was randomly selected. We recorded the extent of visual field loss (as Mean Deviation) and visual acuity (VA) at the time of diagnosis and at the last visit. Beside, we calculated the widest diameter of the remaining central visual field (Figure 4). Low vision and blindness were defined according to WHO criteria, and the major reason for either was noted. The risk for blindness from glaucoma was analyzed by cumulative incidence calculation.
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