... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento... more ... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento y aplicación de las proporciones matemáticas, consideradas por los in-vestigadores como una de las herramientas básicas para aprender el mol (Johnstone, 1974; Henson y Stumbles ...
... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento... more ... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento y aplicación de las proporciones matemáticas, consideradas por los in-vestigadores como una de las herramientas básicas para aprender el mol (Johnstone, 1974; Henson y Stumbles ...
Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants, Nov 26, 2017
The flavonoid 3,5-dihydroxy-7-methoxyflavanone ((-)-alpinone) isolated from sticky resinous exuda... more The flavonoid 3,5-dihydroxy-7-methoxyflavanone ((-)-alpinone) isolated from sticky resinous exudate of Heliotropium huascoense was evaluated as immunostimulatory in mammalian cells . Preliminary observations had showed that (-)-alpinone had increased the expression levels of pro-inflammatory cytokine transcripts in salmonid. Due to high morbidity and mortality that infectious diseases cause in humans, we evaluate the effect of (-)-alpinone as an immunostimulant in mammalian cells. Reactive oxygen species (ROS) are produced by macrophages activators for the destruction of pathogens; we evaluated (-)-alpinone effect in ROS generation and the proliferation of macrophages. The results showed that proliferation in Raw 264.7 cells treated with 10 and 25 μg/mL of (-)-alpinone had a significant increase in macrophage proliferation. In relation to ROS formation, cells treated with 1 and 5 μg/mL of (-)-alpinone, induce ROS formation in macrophages.
Previously, we reported an in vitro evaluation regarding antibacterial effects against F. psychro... more Previously, we reported an in vitro evaluation regarding antibacterial effects against F. psychrophilum by a new Cu (I) complex, [Cu(NN1)2](ClO4). This study presents the results of an in vivo evaluation of [Cu(NN1)2](ClO4) added as a dietary supplement against F. psychrophilum in rainbow trout. The results showed that the administration of [Cu(NN1)2](ClO4) at 29 and 58 µg/g of fish for 15 days does not affect the growth of rainbow trout. On the other hand, the amount of copper present in the liver, intestine, and muscle of rainbow trout was determined. The results showed that the amount of copper in the liver, when compared between treated fish and control fish, does not change. While, in the intestine, an increase in the fish fed at 58 µg/g of fish was observed. In muscle, a slight decrease at 29 µg/g was obtained. Additionally, copper concentrations in the pond water after 15 days of feeding with the [Cu(NN1)2](ClO4) complex showed the highest levels of copper. Finally, the effec...
... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento... more ... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento y aplicación de las proporciones matemáticas, consideradas por los in-vestigadores como una de las herramientas básicas para aprender el mol (Johnstone, 1974; Henson y Stumbles ...
... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento... more ... atómica de Dalton y la reacción química ... 1994), así como los obstáculos en el conocimiento y aplicación de las proporciones matemáticas, consideradas por los in-vestigadores como una de las herramientas básicas para aprender el mol (Johnstone, 1974; Henson y Stumbles ...
Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants, Nov 26, 2017
The flavonoid 3,5-dihydroxy-7-methoxyflavanone ((-)-alpinone) isolated from sticky resinous exuda... more The flavonoid 3,5-dihydroxy-7-methoxyflavanone ((-)-alpinone) isolated from sticky resinous exudate of Heliotropium huascoense was evaluated as immunostimulatory in mammalian cells . Preliminary observations had showed that (-)-alpinone had increased the expression levels of pro-inflammatory cytokine transcripts in salmonid. Due to high morbidity and mortality that infectious diseases cause in humans, we evaluate the effect of (-)-alpinone as an immunostimulant in mammalian cells. Reactive oxygen species (ROS) are produced by macrophages activators for the destruction of pathogens; we evaluated (-)-alpinone effect in ROS generation and the proliferation of macrophages. The results showed that proliferation in Raw 264.7 cells treated with 10 and 25 μg/mL of (-)-alpinone had a significant increase in macrophage proliferation. In relation to ROS formation, cells treated with 1 and 5 μg/mL of (-)-alpinone, induce ROS formation in macrophages.
Previously, we reported an in vitro evaluation regarding antibacterial effects against F. psychro... more Previously, we reported an in vitro evaluation regarding antibacterial effects against F. psychrophilum by a new Cu (I) complex, [Cu(NN1)2](ClO4). This study presents the results of an in vivo evaluation of [Cu(NN1)2](ClO4) added as a dietary supplement against F. psychrophilum in rainbow trout. The results showed that the administration of [Cu(NN1)2](ClO4) at 29 and 58 µg/g of fish for 15 days does not affect the growth of rainbow trout. On the other hand, the amount of copper present in the liver, intestine, and muscle of rainbow trout was determined. The results showed that the amount of copper in the liver, when compared between treated fish and control fish, does not change. While, in the intestine, an increase in the fish fed at 58 µg/g of fish was observed. In muscle, a slight decrease at 29 µg/g was obtained. Additionally, copper concentrations in the pond water after 15 days of feeding with the [Cu(NN1)2](ClO4) complex showed the highest levels of copper. Finally, the effec...
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