Dosimetry based on the detection by electron paramagnetic resonance (EPR) spectroscopy of ionizin... more Dosimetry based on the detection by electron paramagnetic resonance (EPR) spectroscopy of ionizing radiation-induced radicals is an established method for the retrospective dosimetry of past exposures and the dosimetry of potentially exposed persons in radiological emergencies. The dose is estimated by measuring the physical damage induced in materials contained in objects placed on or next to the potentially exposed person. The aim of this paper is to survey the current literature about methodologies and materials that have been proposed for EPR dosimetry, in order to identify those that could be suitable for population triage according to criteria such as ubiquity, non invasiveness and easy sample collection, presence of a post-irradiation EPR signal, negligible background signal, linearity of dose-response relationship, minimum detection limit and post-irradiation signal stability. The paper will survey the features of sugar, plastics, glass, clothing tissues, and solid biologica...
Screen protector glasses are often used to protect the display screen surface of mobile phones ag... more Screen protector glasses are often used to protect the display screen surface of mobile phones against physical damage. Their dosimetric properties were recently studied by thermoluminescence with the aim of using these items as potential emergency dosimeters in the event of a radiological accident. They are sensitive to ionizing radiation and they could be easily removed and replaced without destroying the phone in case of a dose assessment. However, an intrinsic background signal that partially overlaps with the radiation-induced TL signal is observed. The reconstructed dose could be overestimated if not properly taken into account. The homogeneity of this confounding signal on the surface of several screen protectors was estimated and a chemical treatment with hydrofluoric acid (HF 40%) was tested to minimize its contribution. For most of the samples studied, the intrinsic background signal remained a serious issue for dose reconstruction. Additionally, the TL signals were measur...
Creating a sustainable network in biological and retrospective dosimetry that involves a large nu... more Creating a sustainable network in biological and retrospective dosimetry that involves a large number of experienced laboratories throughout the European Union (EU) will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperative action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently needed in an emergency situation. In this regard the European Commission supports the establishment of an European network in biological dosimetry (RENEB). The goal of RENEB is to establish a sustainable European network mainly based on biological dosimetry laboratories involving 23 organisations from 16 countries identified by the TENEB survey, that will guarantee the highest efficiency in the processing and scoring of biological samples for fast, reliable results implemented in the EU emergency management. RENEB will also integrate recent developments in ret...
BACKGROUND Following radioiodine (131I) therapy of differentiated thyroid cancer, the salivary gl... more BACKGROUND Following radioiodine (131I) therapy of differentiated thyroid cancer, the salivary glands may become inflamed, leading to dysfunctions and decreases in patients’ nutritional status and quality of life. The incidence of these dysfunctions after 131I-therapy is poorly known, and no clinical or genetic factors have been identified to date to define at-risk patients, which would allow the delivered activity to be adapted to the expected risk of salivary dysfunctions. OBJECTIVE The aims of this study are to estimate the incidence of salivary dysfunctions, and consequences on the quality of life and nutritional status for patients after 131I-therapy; to characterize at-risk patients of developing posttreatment dysfunctions using clinical, biomolecular, and biochemical factors; and to validate a dosimetric method to calculate the dose received at the salivary gland level for analyzing the dose-response relationship between absorbed doses to salivary glands and salivary dysfunct...
Purpose In the EC funded project RENEB (Realizing the European Network in Biodosimetry), physical... more Purpose In the EC funded project RENEB (Realizing the European Network in Biodosimetry), physical methods applied to fortuitous dosimetric materials are used to complement biological dosimetry, to increase dose assessment capacity for large-scale radiation/nuclear accidents. This paper describes the work performed to implement Optically Stimulated Luminescence (OSL) and Electron Paramagnetic Resonance (EPR) dosimetry techniques. Materials and Methods OSL is applied to electronic components and EPR to touch-screen glass from mobile phones. To implement these new approaches, several blind tests and inter-laboratory comparisons (ILCs) were organized for each assay. Results OSL systems have shown good performances. EPR systems also show good performance in controlled conditions, but ILCs have also demonstrated that post-irradiation exposure to sunlight increases the complexity of the EPR signal analysis. Conclusions Physically based dosimetry techniques present high capacity, new possib...
The increasing risk of a mass casualty scenario following a large scale radiological accident or ... more The increasing risk of a mass casualty scenario following a large scale radiological accident or attack necessitates the development of appropriate dosimetric tools for emergency response. Luminescence dosimetry has been reliably applied for dose reconstruction in contaminated settlements for several decades and recent research into new materials carried close to the human body opens the possibility of estimating individual doses for accident and emergency dosimetry using the same technique. This paper reviews the luminescence research into materials useful for accident dosimetry and applications in retrospective dosimetry. The properties of the materials are critically discussed with regard to the requirements for population triage. It is concluded that electronic components found within portable electronic devices, such as e.g. mobile phones, are at present the most promising material to function as a fortuitous dosimeter in an emergency response.
Retrospective dosimetry using glass has been investigated. Radiation-induced signals have been su... more Retrospective dosimetry using glass has been investigated. Radiation-induced signals have been surveyed for a large number of watch glasses and display windows of mobile phones with TL and EPR techniques in order to study the variability of dosimetric properties among the different types of samples. Dose response, signal stability, and effects of storage conditions are presented.
Dosimetry based on the detection by electron paramagnetic resonance (EPR) spectroscopy of ionizin... more Dosimetry based on the detection by electron paramagnetic resonance (EPR) spectroscopy of ionizing radiation-induced radicals is an established method for the retrospective dosimetry of past exposures and the dosimetry of potentially exposed persons in radiological emergencies. The dose is estimated by measuring the physical damage induced in materials contained in objects placed on or next to the potentially exposed person. The aim of this paper is to survey the current literature about methodologies and materials that have been proposed for EPR dosimetry, in order to identify those that could be suitable for population triage according to criteria such as ubiquity, non invasiveness and easy sample collection, presence of a post-irradiation EPR signal, negligible background signal, linearity of dose-response relationship, minimum detection limit and post-irradiation signal stability. The paper will survey the features of sugar, plastics, glass, clothing tissues, and solid biologica...
Screen protector glasses are often used to protect the display screen surface of mobile phones ag... more Screen protector glasses are often used to protect the display screen surface of mobile phones against physical damage. Their dosimetric properties were recently studied by thermoluminescence with the aim of using these items as potential emergency dosimeters in the event of a radiological accident. They are sensitive to ionizing radiation and they could be easily removed and replaced without destroying the phone in case of a dose assessment. However, an intrinsic background signal that partially overlaps with the radiation-induced TL signal is observed. The reconstructed dose could be overestimated if not properly taken into account. The homogeneity of this confounding signal on the surface of several screen protectors was estimated and a chemical treatment with hydrofluoric acid (HF 40%) was tested to minimize its contribution. For most of the samples studied, the intrinsic background signal remained a serious issue for dose reconstruction. Additionally, the TL signals were measur...
Creating a sustainable network in biological and retrospective dosimetry that involves a large nu... more Creating a sustainable network in biological and retrospective dosimetry that involves a large number of experienced laboratories throughout the European Union (EU) will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperative action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently needed in an emergency situation. In this regard the European Commission supports the establishment of an European network in biological dosimetry (RENEB). The goal of RENEB is to establish a sustainable European network mainly based on biological dosimetry laboratories involving 23 organisations from 16 countries identified by the TENEB survey, that will guarantee the highest efficiency in the processing and scoring of biological samples for fast, reliable results implemented in the EU emergency management. RENEB will also integrate recent developments in ret...
BACKGROUND Following radioiodine (131I) therapy of differentiated thyroid cancer, the salivary gl... more BACKGROUND Following radioiodine (131I) therapy of differentiated thyroid cancer, the salivary glands may become inflamed, leading to dysfunctions and decreases in patients’ nutritional status and quality of life. The incidence of these dysfunctions after 131I-therapy is poorly known, and no clinical or genetic factors have been identified to date to define at-risk patients, which would allow the delivered activity to be adapted to the expected risk of salivary dysfunctions. OBJECTIVE The aims of this study are to estimate the incidence of salivary dysfunctions, and consequences on the quality of life and nutritional status for patients after 131I-therapy; to characterize at-risk patients of developing posttreatment dysfunctions using clinical, biomolecular, and biochemical factors; and to validate a dosimetric method to calculate the dose received at the salivary gland level for analyzing the dose-response relationship between absorbed doses to salivary glands and salivary dysfunct...
Purpose In the EC funded project RENEB (Realizing the European Network in Biodosimetry), physical... more Purpose In the EC funded project RENEB (Realizing the European Network in Biodosimetry), physical methods applied to fortuitous dosimetric materials are used to complement biological dosimetry, to increase dose assessment capacity for large-scale radiation/nuclear accidents. This paper describes the work performed to implement Optically Stimulated Luminescence (OSL) and Electron Paramagnetic Resonance (EPR) dosimetry techniques. Materials and Methods OSL is applied to electronic components and EPR to touch-screen glass from mobile phones. To implement these new approaches, several blind tests and inter-laboratory comparisons (ILCs) were organized for each assay. Results OSL systems have shown good performances. EPR systems also show good performance in controlled conditions, but ILCs have also demonstrated that post-irradiation exposure to sunlight increases the complexity of the EPR signal analysis. Conclusions Physically based dosimetry techniques present high capacity, new possib...
The increasing risk of a mass casualty scenario following a large scale radiological accident or ... more The increasing risk of a mass casualty scenario following a large scale radiological accident or attack necessitates the development of appropriate dosimetric tools for emergency response. Luminescence dosimetry has been reliably applied for dose reconstruction in contaminated settlements for several decades and recent research into new materials carried close to the human body opens the possibility of estimating individual doses for accident and emergency dosimetry using the same technique. This paper reviews the luminescence research into materials useful for accident dosimetry and applications in retrospective dosimetry. The properties of the materials are critically discussed with regard to the requirements for population triage. It is concluded that electronic components found within portable electronic devices, such as e.g. mobile phones, are at present the most promising material to function as a fortuitous dosimeter in an emergency response.
Retrospective dosimetry using glass has been investigated. Radiation-induced signals have been su... more Retrospective dosimetry using glass has been investigated. Radiation-induced signals have been surveyed for a large number of watch glasses and display windows of mobile phones with TL and EPR techniques in order to study the variability of dosimetric properties among the different types of samples. Dose response, signal stability, and effects of storage conditions are presented.
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Papers by C. Bassinet