<b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants i... more <b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression"Environmental Health Perspectives 2005;113(11):1594-1599.Published online 14 Jul 2005PMCID:PMC1310924.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. CYP1A1 is labeled pink to dark red; arrows indicate cells with labeling and the identical cell type without labeling. () CYP1A1 expression in hepatic parenchyma from an Arctic beluga. () Serial section from Arctic beluga shown in () stained using the nonspecific antibody UPC-10. () CYP1A1 expression in hepatic parenchyma from a St. Lawrence beluga. Magnification, 400×.
<b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants i... more <b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression"Environmental Health Perspectives 2005;113(11):1594-1599.Published online 14 Jul 2005PMCID:PMC1310924.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. CYP1A1 is labeled pink to dark red; arrows indicate cells with labeling and the identical cell type without labeling. () CYP1A1 expression in lung endothelium from an Arctic beluga. () CYP1A1 expression in bladder endothelium from an arteriole from an Arctic beluga. () CYP1A1 expression in lung endothelium from an Arctic beluga. () Serial section from Arctic beluga shown in () was labeled using the nonspecific antibody UPC-10. Magnification: , , , 400×; , 200×.
A transitional cell carcinoma of the urinary bladder was found in a beluga whale stranded in the ... more A transitional cell carcinoma of the urinary bladder was found in a beluga whale stranded in the St. Lawrence middle estuary. Various organs of this animal were submitted to high resolution gas chromatography coupled with mass spectrometry analysis. High frequency of urinary bladder cancer in the human population of the same area and the presence of carcinogenic compounds in the marine environment of this animal are discussed.Concurrent isolation of Edwardsiella tarda from various organs of this whale is also reported.
Veterinary Immunology and Immunopathology, Aug 1, 1995
Flow cytometric assays using peripheral blood were developed to study phagocytosis and respirator... more Flow cytometric assays using peripheral blood were developed to study phagocytosis and respiratory burst, the two major functions of neutrophils and among the most important non-specific defense mechanisms, in beluga whales. The use of flow cytometry avoids the problems associated with the isolation and purification of different cell types, and allows the measurement of a large number of cells (10,000) in a very short period of time. The methods described will be used to compare these functions in blood samples from highly contaminated beluga whales from the St. Lawrence and from relatively clean arctic beluga whales.
Wildlife is often killed because it is considered a nuisance. For example, strychnine has been us... more Wildlife is often killed because it is considered a nuisance. For example, strychnine has been used …
... Remis par Marie-Hélène Gravel À Dr Daniel Martineau ... La famille des filovirus est composée... more ... Remis par Marie-Hélène Gravel À Dr Daniel Martineau ... La famille des filovirus est composée du virus Marburg, qui possède un sous-type (Lake Victoria), et du virus Ebola, qui possède à ce jour 4 sous-types : Côte d'Ivoire, Soudan, Zaïre et Reston. (Pourrut et coll. ...
<b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants i... more <b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression"Environmental Health Perspectives 2005;113(11):1594-1599.Published online 14 Jul 2005PMCID:PMC1310924.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. CYP1A1 is labeled pink to dark red; arrows indicate cells with labeling and the identical cell type without labeling. () CYP1A1 expression in the transitional epithelium of bladder; labeling is most intense in the umbrella cells. () Serial section from beluga shown in () labeled using the nonspecific antibody UPC-10. Magnification, 400×.
An isolated population of beluga ( Delphinapterus leucas) inhabits the St Lawrence Estuary, Quebe... more An isolated population of beluga ( Delphinapterus leucas) inhabits the St Lawrence Estuary, Quebec, Canada. This population has failed to recover despite the prohibition of hunting >30 years ago, suggesting the presence of other limiting factors. The authors summarize the reported causes of death and propose risk factors to explain the lack of recovery of this population. From 1983 to 2012, a total of 472 beluga were found stranded. Complete necropsies were carried out on 222 beluga, including 178 adults, 25 juveniles, and 19 newborn calves. Infectious diseases, the most prevalent cause of mortality in this population, accounted for the death of one-third of all beluga (32%). Verminous pneumonia was the cause of mortality of 13 juvenile beluga (52% of juvenile beluga). A total of 39 malignant neoplasms, diagnosed in 35 beluga, caused the death of 31 beluga (20% of beluga >19 years old). Median age at diagnosis of cancer was 48 years (range, 30–61 years). Dystocia and postpartu...
<b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants i... more <b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression"Environmental Health Perspectives 2005;113(11):1594-1599.Published online 14 Jul 2005PMCID:PMC1310924.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. CYP1A1 is labeled pink to dark red; arrows indicate cells with labeling and the identical cell type without labeling. () CYP1A1 expression in hepatic parenchyma from an Arctic beluga. () Serial section from Arctic beluga shown in () stained using the nonspecific antibody UPC-10. () CYP1A1 expression in hepatic parenchyma from a St. Lawrence beluga. Magnification, 400×.
<b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants i... more <b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression"Environmental Health Perspectives 2005;113(11):1594-1599.Published online 14 Jul 2005PMCID:PMC1310924.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. CYP1A1 is labeled pink to dark red; arrows indicate cells with labeling and the identical cell type without labeling. () CYP1A1 expression in lung endothelium from an Arctic beluga. () CYP1A1 expression in bladder endothelium from an arteriole from an Arctic beluga. () CYP1A1 expression in lung endothelium from an Arctic beluga. () Serial section from Arctic beluga shown in () was labeled using the nonspecific antibody UPC-10. Magnification: , , , 400×; , 200×.
A transitional cell carcinoma of the urinary bladder was found in a beluga whale stranded in the ... more A transitional cell carcinoma of the urinary bladder was found in a beluga whale stranded in the St. Lawrence middle estuary. Various organs of this animal were submitted to high resolution gas chromatography coupled with mass spectrometry analysis. High frequency of urinary bladder cancer in the human population of the same area and the presence of carcinogenic compounds in the marine environment of this animal are discussed.Concurrent isolation of Edwardsiella tarda from various organs of this whale is also reported.
Veterinary Immunology and Immunopathology, Aug 1, 1995
Flow cytometric assays using peripheral blood were developed to study phagocytosis and respirator... more Flow cytometric assays using peripheral blood were developed to study phagocytosis and respiratory burst, the two major functions of neutrophils and among the most important non-specific defense mechanisms, in beluga whales. The use of flow cytometry avoids the problems associated with the isolation and purification of different cell types, and allows the measurement of a large number of cells (10,000) in a very short period of time. The methods described will be used to compare these functions in blood samples from highly contaminated beluga whales from the St. Lawrence and from relatively clean arctic beluga whales.
Wildlife is often killed because it is considered a nuisance. For example, strychnine has been us... more Wildlife is often killed because it is considered a nuisance. For example, strychnine has been used …
... Remis par Marie-Hélène Gravel À Dr Daniel Martineau ... La famille des filovirus est composée... more ... Remis par Marie-Hélène Gravel À Dr Daniel Martineau ... La famille des filovirus est composée du virus Marburg, qui possède un sous-type (Lake Victoria), et du virus Ebola, qui possède à ce jour 4 sous-types : Côte d'Ivoire, Soudan, Zaïre et Reston. (Pourrut et coll. ...
<b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants i... more <b>Copyright information:</b>Taken from "Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression"Environmental Health Perspectives 2005;113(11):1594-1599.Published online 14 Jul 2005PMCID:PMC1310924.This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI. CYP1A1 is labeled pink to dark red; arrows indicate cells with labeling and the identical cell type without labeling. () CYP1A1 expression in the transitional epithelium of bladder; labeling is most intense in the umbrella cells. () Serial section from beluga shown in () labeled using the nonspecific antibody UPC-10. Magnification, 400×.
An isolated population of beluga ( Delphinapterus leucas) inhabits the St Lawrence Estuary, Quebe... more An isolated population of beluga ( Delphinapterus leucas) inhabits the St Lawrence Estuary, Quebec, Canada. This population has failed to recover despite the prohibition of hunting >30 years ago, suggesting the presence of other limiting factors. The authors summarize the reported causes of death and propose risk factors to explain the lack of recovery of this population. From 1983 to 2012, a total of 472 beluga were found stranded. Complete necropsies were carried out on 222 beluga, including 178 adults, 25 juveniles, and 19 newborn calves. Infectious diseases, the most prevalent cause of mortality in this population, accounted for the death of one-third of all beluga (32%). Verminous pneumonia was the cause of mortality of 13 juvenile beluga (52% of juvenile beluga). A total of 39 malignant neoplasms, diagnosed in 35 beluga, caused the death of 31 beluga (20% of beluga >19 years old). Median age at diagnosis of cancer was 48 years (range, 30–61 years). Dystocia and postpartu...
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