Increased drought severity is expected in the Mediterranean Basin over the twenty-first century, ... more Increased drought severity is expected in the Mediterranean Basin over the twenty-first century, but our understanding of the potential of most forest tree species to cope with it remains uncertain. In this study, (1) we examined the potential effects of long-term selection and the capacity to respond to future changes in selective pressures in three populations of cork oak (Quercus suber L.). For this purpose, we evaluated the response to dry conditions of 45 open-pollinated trees originating from populations in Morocco, Portugal, and Spain. Growth, leaf size, specific leaf area (SLA), carbon isotope discrimination (Δ13C), leaf nitrogen content (Nmass), and total chlorophyll content (Chlmass) were measured in 9-year-old plants. (2) We also investigated the relationships between functional traits and aboveground growth by regression models. Plants presenting larger and more sclerophyllous leaves (low SLA and high leaf thickness) exhibited higher growths, with results suggesting that these traits are subjected to divergent selection in this species. Heritability estimates were moderately high for Δ13C (0.43 ± 0.25–0.83 ± 0.31) and stem diameter (0.40 ± 0.15–0.71 ± 0.28) for the tree populations. For the rest of the traits (except for annual growth), heritability values varied among populations, particularly for height, leaf size, leaf thickness, and Nmass. Our results suggest that natural selection has led to local adaptations and has also affected the genetic variance intrapopulation in these cork oak populations, although studies with a higher number of populations should be carried out across different years. Additionally, the absence of significant genetic correlations and the fact that correlated traits did not undergo opposing selection provided little evidence for constraints on evolution caused by genetic correlations.
IOPscience is a unique platform for IOP-hosted journal content providing site-wide electronic acc... more IOPscience is a unique platform for IOP-hosted journal content providing site-wide electronic access to more than 130 years of leading scientific research, and incorporates some of the most innovative technologies to enhance your user-experience.
Both fisheries exploitation and increased nutrient loadings strongly affect fish and shellfish ab... more Both fisheries exploitation and increased nutrient loadings strongly affect fish and shellfish abundance and production in estuaries. These stressors do not act independently; instead, they jointly influence food webs, and each affects the sensitivity of species and ecosystems to the other. Nutrient enrichment and the habitat degradation it sometimes causes can affect sustainable yields of fisheries, and fisheries exploitation can affect the ability of estuarine systems to process nutrients. The total biomass of fisheries landings in estuaries and semi-enclosed seas tends to increase with nitrogen loadings in spite of hypoxia, but hypoxia and other negative effects of nutrient over-enrichment cause declines in individual species and in parts of systems most severely affected. More thoroughly integrated management of nutrients and fisheries will permit more effective management responses to systems affected by both stressors, including the application of fisheries regulations to rebuild stocks negatively affected by eutrophication. Reducing fishing mortality may lead to the recovery of depressed populations even when eutrophication contributes to population declines if actions are taken while the population retains sufficient reproductive potential. New advances in modeling, statistics, and technology promise to provide the information needed to improve the understanding and management of systems subject to both nutrient enrichment and fisheries exploitation.
The surface behavior of Supramolecular Structures as inclusion complexes[1] were studied. The inc... more The surface behavior of Supramolecular Structures as inclusion complexes[1] were studied. The inclusion complexes (ICs) obtained from the threading of α-cyclodextrin (α-CD) with poly(ε-caprolactone) (PEC) and derivatives as precursor homopolymers were prepared and characterized by 1H-NMR and FT-IR Microscopy. In order to investigate the influence of the chemical structure of the other precursor homopolymers as poly(ethylene oxide) (PEO) and poly(tetrahydrofuran) (PTHF), the inclusion complexes (ICs) were also obtained from the threading of α-cyclodextrin (α-CD) with these polymers. Surface pressure-area isotherm (π-A) at the air-water interface were determined by the Langmuir Technique for all the ICs and their polymers. Due to solubility reasons, different spreading solvents were used. In a set of control experiments, it was observed that the spreading volume did not influence significantly the isotherms for any polymeric systems studied. It was found that the hydrophobic and hydrophilic balance changes with the increasing of the methylene and hydroxyls groups number in the chemical structures of the precursor polymers involved in the ICs. The degree of hydrophobicity of the different supramolecular systems was also estimated from the determination of the surface free energy (SE) values using the wettability measurements.[2] In order to describe the experimental behavior of the ICs and the precursor polymers, molecular dynamics simulation (MDS) were performed. The radial distribution functions (RDF) between water molecules and hydrophilic and hydrophobic moieties of the polymeric systems studied were analized. By this way it was possible to visualize the orientation and the organization of these supramolecular structures at the air-water interface.
The reactions of the water-soluble chelating phosphines 1,2-bis(bis(hydroxyalkyl)phosphino)ethane... more The reactions of the water-soluble chelating phosphines 1,2-bis(bis(hydroxyalkyl)phosphino)ethane (alkyl = n-propyl, DHPrPE; n-butyl, DHBuPE; n-pentyl, DHPePE) with FeCl(2).4H(2)O and FeSO(4).7H(2)O were studied as routes to water-soluble complexes that will bind small molecules, dinitrogen in particular. The products that form and their stereochemistry depend on the solvent, the counteranion, and the alkyl chain length on the phosphine. In alcoholic solvents, the reaction of FeCl(2).4H(2)O with 2 equiv of DHBuPE or DHPePE gave trans-Fe(L(2))(2)Cl(2). The analogous reactions in water with DHBuPE and DHPePE gave only cis products, and the reaction of FeSO(4).7H(2)O with any of the phosphines gave only cis-Fe(L(2))(2)SO(4). These results are interpreted as follows. The trans stereochemistry of the products from the reactions of FeCl(2).4H(2)O in alcohols is suggested to be the consequence of the trans geometry of the Fe(H(2)O)(4)Cl(2) complex, i.e., substitution of the water molecules by the phosphines retains the geometry of the starting material. The formation of cis-Fe(DHPrPE)(2)Cl(2) is an exception to this result because the coordination of two -OH groups forms two six-membered rings, as shown in the X-ray structure of the molecule. DHBuPE and DHPePE reacted with FeSO(4).7H(2)O in water to initially yield cis-Fe(P(2))(2)SO(4) compounds, but subsequent substitution reactions occurred over several hours to give sequentially trans-Fe(DHBuPE)(2)(H(2)O)(SO(4)) and then trans-[Fe(DHBuPE)(2)(H(2)O)(2)]SO(4). The rate constants and activation reactions for these aquation reactions were determined and are consistent with dissociatively activated mechanisms. The cis- and trans-Fe(L(2))(2)X (X = (Cl)(2) or SO(4)) complexes react with N(2), CO, and CH(3)CN to yield trans complexes with bound N(2), CO, or CH(3)CN. The crystal structures of the cis-Fe(DHPrPE)(2)SO(4), trans-Fe(DHPrPE)(2)(CO)SO(4), trans-Fe(DHBuPE)(2)Cl(2), trans-[Fe(DHBuPE)(2)(CO)(Cl)][B(C(6)H(5))(4)], trans-Fe(DMeOPrPE)(2)Cl(2), trans-Fe(DMeOPrPE)(2)Br(2), and trans-[Fe(DHBuPE)(2)Cl(2)]Cl complexes are reported. As expected from using water-soluble phosphines, the complexes reported herein are water soluble (generally greater than 0.5 M at 23 degrees C).
We present a framework for the co-ordinated, autonomic management of multiple clusters in a compu... more We present a framework for the co-ordinated, autonomic management of multiple clusters in a compute center and their integration into a Grid environment. Site autonomy and the automation of administrative tasks are prime aspects in this framework. The system behavior is continuously monitored in a steering cycle and appropriate actions are taken to resolve any problems. All presented components have been implemented in the course of the EU project DataGrid: The Lemon monitoring components, the FT fault-tolerance mechanism, the quattor system for software installation and configuration, the RMS job and resource management system, and the Gridification scheme that integrates clusters into the Grid.
This paper examines statistical analysis of social reciprocity at group, dyadic, and individual l... more This paper examines statistical analysis of social reciprocity at group, dyadic, and individual levels. Given that testing statistical hypotheses regarding social reciprocity can be also of interest, a statistical procedure based on Monte Carlo sampling has been developed and implemented in R in order to allow social researchers to describe groups and make statistical decisions.
International Journal of Human Resource Management, 2011
Research on work–life balance (WLB) practices has increased in recent years. Academics affirm tha... more Research on work–life balance (WLB) practices has increased in recent years. Academics affirm that the implementation of WLB practices helps to achieve better organizational results and improve employee outcomes such as higher satisfaction and commitment, and reduce turnover intentions. However, some authors have argued that there are differences between the availability of WLB practices in companies and employees' perceptions of access to such practices. The literature on the differences in perceptions between managers and employees in relation to WLB and its effects is sparse. Using two samples of 229 managers and 511 employees from the same firms, we in this paper contribute to our knowledge of the existence of the perception gaps between managers and employees and their influence on the take-up of WLB. Implications for academics and practitioners are discussed.
Social reciprocity may explain certain emerging psychological processes likely to be founded on d... more Social reciprocity may explain certain emerging psychological processes likely to be founded on dyadic relations. Although indexes and statistics have been proposed to measure and make statistical decisions regarding social reciprocity in groups, these tools were generally developed to identify association patterns rather than to quantify the discrepancies between what each individual addresses to his or her partners and what is received from those partners in return. Additionally, social researchers’ interest extends beyond measuring groups at the global level because dyadic and individual measurements are also necessary for proper descriptions of social interactions. This study is concerned with a new statistic for measuring social reciprocity at the global level and with decomposing that statistic in order to identify which dyads and individuals account for a significant part of asymmetry in social interactions. In addition to a set of indexes, some exact analytical results are derived, and a way of making statistical decisions is proposed.
This paper examines statistical analysis of social reciprocity, that is, the balance between addr... more This paper examines statistical analysis of social reciprocity, that is, the balance between addressing and receiving behaviour in social interactions. Specifically, it focuses on the measurement of social reciprocity by means of directionality and skew-symmetry statistics at different levels. Two statistics have been used as overall measures of social reciprocity at group level: the directional consistency and the skew-symmetry statistics. Furthermore, the skew-symmetry statistic allows social researchers to obtain complementary information at dyadic and individual levels. However, having computed these measures, social researchers may be interested in testing statistical hypotheses regarding social reciprocity. For this reason, it has been developed a statistical procedure, based on Monte Carlo sampling, in order to allow social researchers to describe groups and make statistical decisions.
Purpose Our aim was to review our single-centre experience regarding imaging features and patholo... more Purpose Our aim was to review our single-centre experience regarding imaging features and pathological conditions arising from enlarged lymph nodes following orthotopic liver transplantation (OLD) and identify imaging features that may allow narrowing the differential diagnosis. Materials and methods Between January 1997 and September 2008, 715 OLTs were performed at our Institution in 585 patients. In 19 patients (2.6 %) ultrasound (US) showed enlarged lymph nodes in the upper abdomen, and abdominal computed tomography (CT) was performed Results Histological results showed posttransplantation lymphoproliferative disorder (PTLD) in six patients (31.5 %), hepatic tumoral disease in six (31.5 %), disseminated systemic tuberculosis in one (5.2%) and sarcoidosis in one (5.2%). Histological results showed nonspecific reactive lymph node hyperplasia in five patients (26%). Conclusions Detecting enlarged lymph nodes in the upper abdomen after liver transplantation is and infrequent occurrence; however, thorough imaging is required to detect and characterise a wide variety of disorders. Most of the time, enlarged lymph nodes will be related to posttransplantation lymphoproliferative disorder or tumoral recurrence. Obiettivo Il trapianto ortotopico di fegato (OLT) è il trattamento di scelta per le patologie epatiche allo stadio avanzato. In seguito a OLT, si possono sviluppare una serie di malattie che si manifestano con la presenza linfoadenomegalie nell’addome superiore. Materiali e metodi Tra gennaio 1995 e settembre 2006, nel nostro Istituto sono state effettuate 715 OLT in 585 pazienti. In 19 di questi (2,6%), l’ecografia ha evidenziato la presenza di linfoadenomegalie nell’addome superiore ed è quindi stata effettuata una indagine con tomografia computerizzata (TC). Risultati Gli esami istologici hanno rivelato un disturbo linfoproliferativo post-trapianto (PTLD) in 6 pazienti (31,5%), una neoplasia epatica in 6 pazienti (31,5%), una tubercolosi sistemica disseminata in un caso (5,2%) ed una sarcoidosi in un altro caso (5,2%). In 5 pazienti (26%) l’esame istologico ha evidenziato un’iperplasia linfonodale reattiva non specifica. Conclusioni Il rilevamento di linfoadenomegalie nell’addome superiore dopo trapianto di fegato è poco frequente, ma un imaging accurato è necessario per diagnosticare e caratterizzare un’ampia varietà di patologie. Nella maggior parte dei casi le linfoadenomegalie si riveleranno correlate ad un disordine linfoproliferativo post-trapianto o ad una recidiva di malattia.
The patient is a previously healthy 28-year-old woman with incidentally detected focal liver lesi... more The patient is a previously healthy 28-year-old woman with incidentally detected focal liver lesion. On CT, the tumor showed brisk arterial enhancement and persistent hyperenhancement on portal and delayed phases. Histological study showed spindle cells without atypia and immunohistochemical study was consistent with leiomyoma.
Increased drought severity is expected in the Mediterranean Basin over the twenty-first century, ... more Increased drought severity is expected in the Mediterranean Basin over the twenty-first century, but our understanding of the potential of most forest tree species to cope with it remains uncertain. In this study, (1) we examined the potential effects of long-term selection and the capacity to respond to future changes in selective pressures in three populations of cork oak (Quercus suber L.). For this purpose, we evaluated the response to dry conditions of 45 open-pollinated trees originating from populations in Morocco, Portugal, and Spain. Growth, leaf size, specific leaf area (SLA), carbon isotope discrimination (Δ13C), leaf nitrogen content (Nmass), and total chlorophyll content (Chlmass) were measured in 9-year-old plants. (2) We also investigated the relationships between functional traits and aboveground growth by regression models. Plants presenting larger and more sclerophyllous leaves (low SLA and high leaf thickness) exhibited higher growths, with results suggesting that these traits are subjected to divergent selection in this species. Heritability estimates were moderately high for Δ13C (0.43 ± 0.25–0.83 ± 0.31) and stem diameter (0.40 ± 0.15–0.71 ± 0.28) for the tree populations. For the rest of the traits (except for annual growth), heritability values varied among populations, particularly for height, leaf size, leaf thickness, and Nmass. Our results suggest that natural selection has led to local adaptations and has also affected the genetic variance intrapopulation in these cork oak populations, although studies with a higher number of populations should be carried out across different years. Additionally, the absence of significant genetic correlations and the fact that correlated traits did not undergo opposing selection provided little evidence for constraints on evolution caused by genetic correlations.
IOPscience is a unique platform for IOP-hosted journal content providing site-wide electronic acc... more IOPscience is a unique platform for IOP-hosted journal content providing site-wide electronic access to more than 130 years of leading scientific research, and incorporates some of the most innovative technologies to enhance your user-experience.
Both fisheries exploitation and increased nutrient loadings strongly affect fish and shellfish ab... more Both fisheries exploitation and increased nutrient loadings strongly affect fish and shellfish abundance and production in estuaries. These stressors do not act independently; instead, they jointly influence food webs, and each affects the sensitivity of species and ecosystems to the other. Nutrient enrichment and the habitat degradation it sometimes causes can affect sustainable yields of fisheries, and fisheries exploitation can affect the ability of estuarine systems to process nutrients. The total biomass of fisheries landings in estuaries and semi-enclosed seas tends to increase with nitrogen loadings in spite of hypoxia, but hypoxia and other negative effects of nutrient over-enrichment cause declines in individual species and in parts of systems most severely affected. More thoroughly integrated management of nutrients and fisheries will permit more effective management responses to systems affected by both stressors, including the application of fisheries regulations to rebuild stocks negatively affected by eutrophication. Reducing fishing mortality may lead to the recovery of depressed populations even when eutrophication contributes to population declines if actions are taken while the population retains sufficient reproductive potential. New advances in modeling, statistics, and technology promise to provide the information needed to improve the understanding and management of systems subject to both nutrient enrichment and fisheries exploitation.
The surface behavior of Supramolecular Structures as inclusion complexes[1] were studied. The inc... more The surface behavior of Supramolecular Structures as inclusion complexes[1] were studied. The inclusion complexes (ICs) obtained from the threading of α-cyclodextrin (α-CD) with poly(ε-caprolactone) (PEC) and derivatives as precursor homopolymers were prepared and characterized by 1H-NMR and FT-IR Microscopy. In order to investigate the influence of the chemical structure of the other precursor homopolymers as poly(ethylene oxide) (PEO) and poly(tetrahydrofuran) (PTHF), the inclusion complexes (ICs) were also obtained from the threading of α-cyclodextrin (α-CD) with these polymers. Surface pressure-area isotherm (π-A) at the air-water interface were determined by the Langmuir Technique for all the ICs and their polymers. Due to solubility reasons, different spreading solvents were used. In a set of control experiments, it was observed that the spreading volume did not influence significantly the isotherms for any polymeric systems studied. It was found that the hydrophobic and hydrophilic balance changes with the increasing of the methylene and hydroxyls groups number in the chemical structures of the precursor polymers involved in the ICs. The degree of hydrophobicity of the different supramolecular systems was also estimated from the determination of the surface free energy (SE) values using the wettability measurements.[2] In order to describe the experimental behavior of the ICs and the precursor polymers, molecular dynamics simulation (MDS) were performed. The radial distribution functions (RDF) between water molecules and hydrophilic and hydrophobic moieties of the polymeric systems studied were analized. By this way it was possible to visualize the orientation and the organization of these supramolecular structures at the air-water interface.
The reactions of the water-soluble chelating phosphines 1,2-bis(bis(hydroxyalkyl)phosphino)ethane... more The reactions of the water-soluble chelating phosphines 1,2-bis(bis(hydroxyalkyl)phosphino)ethane (alkyl = n-propyl, DHPrPE; n-butyl, DHBuPE; n-pentyl, DHPePE) with FeCl(2).4H(2)O and FeSO(4).7H(2)O were studied as routes to water-soluble complexes that will bind small molecules, dinitrogen in particular. The products that form and their stereochemistry depend on the solvent, the counteranion, and the alkyl chain length on the phosphine. In alcoholic solvents, the reaction of FeCl(2).4H(2)O with 2 equiv of DHBuPE or DHPePE gave trans-Fe(L(2))(2)Cl(2). The analogous reactions in water with DHBuPE and DHPePE gave only cis products, and the reaction of FeSO(4).7H(2)O with any of the phosphines gave only cis-Fe(L(2))(2)SO(4). These results are interpreted as follows. The trans stereochemistry of the products from the reactions of FeCl(2).4H(2)O in alcohols is suggested to be the consequence of the trans geometry of the Fe(H(2)O)(4)Cl(2) complex, i.e., substitution of the water molecules by the phosphines retains the geometry of the starting material. The formation of cis-Fe(DHPrPE)(2)Cl(2) is an exception to this result because the coordination of two -OH groups forms two six-membered rings, as shown in the X-ray structure of the molecule. DHBuPE and DHPePE reacted with FeSO(4).7H(2)O in water to initially yield cis-Fe(P(2))(2)SO(4) compounds, but subsequent substitution reactions occurred over several hours to give sequentially trans-Fe(DHBuPE)(2)(H(2)O)(SO(4)) and then trans-[Fe(DHBuPE)(2)(H(2)O)(2)]SO(4). The rate constants and activation reactions for these aquation reactions were determined and are consistent with dissociatively activated mechanisms. The cis- and trans-Fe(L(2))(2)X (X = (Cl)(2) or SO(4)) complexes react with N(2), CO, and CH(3)CN to yield trans complexes with bound N(2), CO, or CH(3)CN. The crystal structures of the cis-Fe(DHPrPE)(2)SO(4), trans-Fe(DHPrPE)(2)(CO)SO(4), trans-Fe(DHBuPE)(2)Cl(2), trans-[Fe(DHBuPE)(2)(CO)(Cl)][B(C(6)H(5))(4)], trans-Fe(DMeOPrPE)(2)Cl(2), trans-Fe(DMeOPrPE)(2)Br(2), and trans-[Fe(DHBuPE)(2)Cl(2)]Cl complexes are reported. As expected from using water-soluble phosphines, the complexes reported herein are water soluble (generally greater than 0.5 M at 23 degrees C).
We present a framework for the co-ordinated, autonomic management of multiple clusters in a compu... more We present a framework for the co-ordinated, autonomic management of multiple clusters in a compute center and their integration into a Grid environment. Site autonomy and the automation of administrative tasks are prime aspects in this framework. The system behavior is continuously monitored in a steering cycle and appropriate actions are taken to resolve any problems. All presented components have been implemented in the course of the EU project DataGrid: The Lemon monitoring components, the FT fault-tolerance mechanism, the quattor system for software installation and configuration, the RMS job and resource management system, and the Gridification scheme that integrates clusters into the Grid.
This paper examines statistical analysis of social reciprocity at group, dyadic, and individual l... more This paper examines statistical analysis of social reciprocity at group, dyadic, and individual levels. Given that testing statistical hypotheses regarding social reciprocity can be also of interest, a statistical procedure based on Monte Carlo sampling has been developed and implemented in R in order to allow social researchers to describe groups and make statistical decisions.
International Journal of Human Resource Management, 2011
Research on work–life balance (WLB) practices has increased in recent years. Academics affirm tha... more Research on work–life balance (WLB) practices has increased in recent years. Academics affirm that the implementation of WLB practices helps to achieve better organizational results and improve employee outcomes such as higher satisfaction and commitment, and reduce turnover intentions. However, some authors have argued that there are differences between the availability of WLB practices in companies and employees' perceptions of access to such practices. The literature on the differences in perceptions between managers and employees in relation to WLB and its effects is sparse. Using two samples of 229 managers and 511 employees from the same firms, we in this paper contribute to our knowledge of the existence of the perception gaps between managers and employees and their influence on the take-up of WLB. Implications for academics and practitioners are discussed.
Social reciprocity may explain certain emerging psychological processes likely to be founded on d... more Social reciprocity may explain certain emerging psychological processes likely to be founded on dyadic relations. Although indexes and statistics have been proposed to measure and make statistical decisions regarding social reciprocity in groups, these tools were generally developed to identify association patterns rather than to quantify the discrepancies between what each individual addresses to his or her partners and what is received from those partners in return. Additionally, social researchers’ interest extends beyond measuring groups at the global level because dyadic and individual measurements are also necessary for proper descriptions of social interactions. This study is concerned with a new statistic for measuring social reciprocity at the global level and with decomposing that statistic in order to identify which dyads and individuals account for a significant part of asymmetry in social interactions. In addition to a set of indexes, some exact analytical results are derived, and a way of making statistical decisions is proposed.
This paper examines statistical analysis of social reciprocity, that is, the balance between addr... more This paper examines statistical analysis of social reciprocity, that is, the balance between addressing and receiving behaviour in social interactions. Specifically, it focuses on the measurement of social reciprocity by means of directionality and skew-symmetry statistics at different levels. Two statistics have been used as overall measures of social reciprocity at group level: the directional consistency and the skew-symmetry statistics. Furthermore, the skew-symmetry statistic allows social researchers to obtain complementary information at dyadic and individual levels. However, having computed these measures, social researchers may be interested in testing statistical hypotheses regarding social reciprocity. For this reason, it has been developed a statistical procedure, based on Monte Carlo sampling, in order to allow social researchers to describe groups and make statistical decisions.
Purpose Our aim was to review our single-centre experience regarding imaging features and patholo... more Purpose Our aim was to review our single-centre experience regarding imaging features and pathological conditions arising from enlarged lymph nodes following orthotopic liver transplantation (OLD) and identify imaging features that may allow narrowing the differential diagnosis. Materials and methods Between January 1997 and September 2008, 715 OLTs were performed at our Institution in 585 patients. In 19 patients (2.6 %) ultrasound (US) showed enlarged lymph nodes in the upper abdomen, and abdominal computed tomography (CT) was performed Results Histological results showed posttransplantation lymphoproliferative disorder (PTLD) in six patients (31.5 %), hepatic tumoral disease in six (31.5 %), disseminated systemic tuberculosis in one (5.2%) and sarcoidosis in one (5.2%). Histological results showed nonspecific reactive lymph node hyperplasia in five patients (26%). Conclusions Detecting enlarged lymph nodes in the upper abdomen after liver transplantation is and infrequent occurrence; however, thorough imaging is required to detect and characterise a wide variety of disorders. Most of the time, enlarged lymph nodes will be related to posttransplantation lymphoproliferative disorder or tumoral recurrence. Obiettivo Il trapianto ortotopico di fegato (OLT) è il trattamento di scelta per le patologie epatiche allo stadio avanzato. In seguito a OLT, si possono sviluppare una serie di malattie che si manifestano con la presenza linfoadenomegalie nell’addome superiore. Materiali e metodi Tra gennaio 1995 e settembre 2006, nel nostro Istituto sono state effettuate 715 OLT in 585 pazienti. In 19 di questi (2,6%), l’ecografia ha evidenziato la presenza di linfoadenomegalie nell’addome superiore ed è quindi stata effettuata una indagine con tomografia computerizzata (TC). Risultati Gli esami istologici hanno rivelato un disturbo linfoproliferativo post-trapianto (PTLD) in 6 pazienti (31,5%), una neoplasia epatica in 6 pazienti (31,5%), una tubercolosi sistemica disseminata in un caso (5,2%) ed una sarcoidosi in un altro caso (5,2%). In 5 pazienti (26%) l’esame istologico ha evidenziato un’iperplasia linfonodale reattiva non specifica. Conclusioni Il rilevamento di linfoadenomegalie nell’addome superiore dopo trapianto di fegato è poco frequente, ma un imaging accurato è necessario per diagnosticare e caratterizzare un’ampia varietà di patologie. Nella maggior parte dei casi le linfoadenomegalie si riveleranno correlate ad un disordine linfoproliferativo post-trapianto o ad una recidiva di malattia.
The patient is a previously healthy 28-year-old woman with incidentally detected focal liver lesi... more The patient is a previously healthy 28-year-old woman with incidentally detected focal liver lesion. On CT, the tumor showed brisk arterial enhancement and persistent hyperenhancement on portal and delayed phases. Histological study showed spindle cells without atypia and immunohistochemical study was consistent with leiomyoma.
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