BackgroundIn the literature, there is not sufficient data on factors affecting the development of... more BackgroundIn the literature, there is not sufficient data on factors affecting the development of complications in patients with penile fracture after early surgical intervention.ObjectivesTo investigate the predictors of long‐term complications in patients who underwent immediate surgical repair for penile fracture.Materials/methodsThis clinical study included a total of 31 cases of penile fracture in which surgical treatment was performed within the first 24 h and penile fracture was confirmed during the operation. The patients with and without late complications were compared in terms of parameters such as age, tear size of the tunica albuginea of the penis, bilateral involvement of the corpora cavernosa involvement, urethral injuries, and duration from penile fracture to surgery.ResultsThe median age of the patients was 42 years (interquartile range: 34–51 years). The median time from penile fracture to surgery was 13 h (8–18 h). The median tear size was 16 mm (11–21 mm). Late complications were seen in 13 (41.9%) patients in the post‐operative period. Erectile dysfunction developed in five (16.1%) patients in the post‐operative period. There was no statistically significant relationship between age, tear size, time from penile fracture to surgery, and bilateral corporeal involvement in terms of erectile dysfunction development. Painful erections, penile deviations, urethral strictures, tunical scars, and re‐fracture were the other late complications. There was a significant relationship between the development of any complication and time from penile fracture to surgery (p = 0.028) and tear size (p = 0.031). In the receiver operating characteristic analysis of complication development, the cut‐off value for the time from penile fracture to surgery was 13.5 h.Discussion and conclusionWe found that the longer time interval between penile fracture and surgery worsened the patient outcomes. In addition, tear size was determined to be a predictor for long‐term complications. In our opinion, early treatment of penile fracture can prevent severe complications in these cases.
Prolaktinin (PRL) spermatogenez ve sperm parametreleri uzerine olan etkisi henuz kesinlesmemistir... more Prolaktinin (PRL) spermatogenez ve sperm parametreleri uzerine olan etkisi henuz kesinlesmemistir. Infertilite olgularinda hiperprolaktinemi ve spermatogenez arasindaki iliskiyi degerlendirmek amaci ile 85 infertil ve hiperprolaktinemili hastayi arastirdik. Olgularimizin hepsinde serum PRL, folikul stimulan hormon, luteinizan hormon, total testosteron duzeyi tayinleri ve en az iki semen analizi yapilmistir. Hiperprolaktinemi saptanan olgularda bromokriptin mesilat tedavisine baslanmis ve 24 aylik bir sure sonunda PRL duzeyleri normale donmus, ancak bu durum semen analizi parametrelerine yansimamistir. Sonuc olarak hiperprolaktineminin sperm sayi, morfolojisi ve motilitesine etkisinin az oldugunu ve tedavisinin erkek infertilitesi tedavisinde katkisinin anlamli olmadigini saptadik.
Administration of vasoactive drugs intracavernously is a well-known easily used and inexpensive a... more Administration of vasoactive drugs intracavernously is a well-known easily used and inexpensive alternative in treatment of a certain group of patients with erectile dysfunction. There are a few drugs used for this purpose, but we prefer papaverine as the first choice because it is easily available and inexpensive in our country. We used alprostadil only in nonresponders to papaverine or if there was any complication with papaverine. We present a series of 69 patients, 24 with psychogenic (34.8%), 27 with organic (39.1%), and 18 (26.1) with mixed etiology of erectile dysfunction, treated with intracavernous self-injection therapy. Mean follow-up of the patients was 13.6 months (7-30 months). In this study, 3,430 papaverine and 780 alprostadil injections were performed in 56 and 13 patients, respectively. In 75% of the papaverine injections and in 83% of the alprostadil injections, erections were achieved sufficient for sexual intercourse. During the follow-up, there were not any abnormal alterations in liver function tests. The main complaint of the patients who used papaverine was a burning sensation (98%) during administration of the drug, which did not last more than 1 minute. Of 13 patients in the alprostadil group, 56.9% of the patients complained mainly of discomfort during erection. We concluded that intracavernous therapy is a good and inexpensive option in the management of erectile dysfunction in carefully selected patients.
BackgroundIn the literature, there is not sufficient data on factors affecting the development of... more BackgroundIn the literature, there is not sufficient data on factors affecting the development of complications in patients with penile fracture after early surgical intervention.ObjectivesTo investigate the predictors of long‐term complications in patients who underwent immediate surgical repair for penile fracture.Materials/methodsThis clinical study included a total of 31 cases of penile fracture in which surgical treatment was performed within the first 24 h and penile fracture was confirmed during the operation. The patients with and without late complications were compared in terms of parameters such as age, tear size of the tunica albuginea of the penis, bilateral involvement of the corpora cavernosa involvement, urethral injuries, and duration from penile fracture to surgery.ResultsThe median age of the patients was 42 years (interquartile range: 34–51 years). The median time from penile fracture to surgery was 13 h (8–18 h). The median tear size was 16 mm (11–21 mm). Late complications were seen in 13 (41.9%) patients in the post‐operative period. Erectile dysfunction developed in five (16.1%) patients in the post‐operative period. There was no statistically significant relationship between age, tear size, time from penile fracture to surgery, and bilateral corporeal involvement in terms of erectile dysfunction development. Painful erections, penile deviations, urethral strictures, tunical scars, and re‐fracture were the other late complications. There was a significant relationship between the development of any complication and time from penile fracture to surgery (p = 0.028) and tear size (p = 0.031). In the receiver operating characteristic analysis of complication development, the cut‐off value for the time from penile fracture to surgery was 13.5 h.Discussion and conclusionWe found that the longer time interval between penile fracture and surgery worsened the patient outcomes. In addition, tear size was determined to be a predictor for long‐term complications. In our opinion, early treatment of penile fracture can prevent severe complications in these cases.
Prolaktinin (PRL) spermatogenez ve sperm parametreleri uzerine olan etkisi henuz kesinlesmemistir... more Prolaktinin (PRL) spermatogenez ve sperm parametreleri uzerine olan etkisi henuz kesinlesmemistir. Infertilite olgularinda hiperprolaktinemi ve spermatogenez arasindaki iliskiyi degerlendirmek amaci ile 85 infertil ve hiperprolaktinemili hastayi arastirdik. Olgularimizin hepsinde serum PRL, folikul stimulan hormon, luteinizan hormon, total testosteron duzeyi tayinleri ve en az iki semen analizi yapilmistir. Hiperprolaktinemi saptanan olgularda bromokriptin mesilat tedavisine baslanmis ve 24 aylik bir sure sonunda PRL duzeyleri normale donmus, ancak bu durum semen analizi parametrelerine yansimamistir. Sonuc olarak hiperprolaktineminin sperm sayi, morfolojisi ve motilitesine etkisinin az oldugunu ve tedavisinin erkek infertilitesi tedavisinde katkisinin anlamli olmadigini saptadik.
Administration of vasoactive drugs intracavernously is a well-known easily used and inexpensive a... more Administration of vasoactive drugs intracavernously is a well-known easily used and inexpensive alternative in treatment of a certain group of patients with erectile dysfunction. There are a few drugs used for this purpose, but we prefer papaverine as the first choice because it is easily available and inexpensive in our country. We used alprostadil only in nonresponders to papaverine or if there was any complication with papaverine. We present a series of 69 patients, 24 with psychogenic (34.8%), 27 with organic (39.1%), and 18 (26.1) with mixed etiology of erectile dysfunction, treated with intracavernous self-injection therapy. Mean follow-up of the patients was 13.6 months (7-30 months). In this study, 3,430 papaverine and 780 alprostadil injections were performed in 56 and 13 patients, respectively. In 75% of the papaverine injections and in 83% of the alprostadil injections, erections were achieved sufficient for sexual intercourse. During the follow-up, there were not any abnormal alterations in liver function tests. The main complaint of the patients who used papaverine was a burning sensation (98%) during administration of the drug, which did not last more than 1 minute. Of 13 patients in the alprostadil group, 56.9% of the patients complained mainly of discomfort during erection. We concluded that intracavernous therapy is a good and inexpensive option in the management of erectile dysfunction in carefully selected patients.
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