Oxidative stress is one of the most significant risk factors for degenerative disease. Dietary ha... more Oxidative stress is one of the most significant risk factors for degenerative disease. Dietary habits can play a key role in regulating the redox status of human plasma, improving the defense against oxidative damage. Oxidative stress represents an imbalance between humans’ protective molecules, the antioxidants, and molecules able to damage all sorts of cellular components, the free radicals. An inadequate intake of antioxidant nutrients may compromise antioxidant potential, thus compounding overall oxidative stress. The levels of dietary antioxidants in human tissues are strictly related to the amount and food composition of the diet and to their bioavailability, highlighting the importance of interindividual genetic variation. A well-balanced overall dietary pattern and a healthy lifestyle contribute to a higher quality of life, and although new epidemiological and intervention clinical trials could improve our knowledge of the role of antioxidant status in health and disease, the Mediterranean diet seems to be a daily recommended diet for a healthy lifestyle.
There is mounting evidence emphasizing the importance of intracellular antioxidant levels for mai... more There is mounting evidence emphasizing the importance of intracellular antioxidant levels for maintenance of the immune function. The flavonoid quercetin, a natural antioxidant, has been shown to modulate enzymes involved in the regulation of the inflammatory response. However, up to now, there have been no studies describing quercetin levels in cells of the immune system. A gradient reversed-phase HPLC technique
Endocrine, metabolic & immune disorders, Mar 1, 2023
Background: The adipose tissue influences by an extensive crosstalk at the local and systemic lev... more Background: The adipose tissue influences by an extensive crosstalk at the local and systemic level the energy balance, including storage, mobilization, and utilization at both central and peripheral sites in response to specific external stimuli or metabolic changes. The balance between energy intake and expenditure is a delicate equilibrium among multifactorial aspects ranging from genetic to environmental influences. Aim: The evidence from several recently published papers dealing with the topic of the beneficial health effects of micronutrient and plant bioactive compounds on obesity and/or comorbidities has been reported in this paper. Methodology: MEDLINE database (PubMed database; National Library of Medicine, Bethesda, MD and Google Scholar) was searched by combining the terms of specific micronutrients and/or plant bioactive compounds associated with obesity and related comorbidities. All English language manuscripts published between 2005 and 2021 in the MEDLINE database were searched, selected, and reviewed here. Conclusion: People do not consume single food or ingredients but global composite diets; thus, the evaluation of mechanisms of action, efficacy and safety of vitamins and mineral and natural bioactive compounds is still a challenge in research on nutrition and food supplements.
The conversion of a conventional farm to the methods of the organic farming is a very critical st... more The conversion of a conventional farm to the methods of the organic farming is a very critical stage of technical and economical investment. From an agronomical point of view, usually the conversion needs a very different length of time with respect to that set by the regulation, because the organic farming is based on the soil fertility and, in general, on the preservation at the equilibrium of the farm’s ecosystem. These elements affect time and method of the conversions that, although based on clear principles, can require different interventions and solutions and give different results in different times depending on the starting conditions of fertility, farm organization, operating possibilities and knowledge. A research project has been funded by the Lazio Region (central Italy) into the Interregional Programme Agriculture Quality with the general objective to monitor the soil characteristics and biodiversity, the quality of the products as well as to study the economical aspe...
The interrelationship between habitual alcohol consumption, dietary intakes and vitamin status wa... more The interrelationship between habitual alcohol consumption, dietary intakes and vitamin status was examined in 393 elderly subjects (188 men, 205 women, age range 65-90 years) resident in seven retirement homes throughout Italy. Individual food intake was assessed by the 7-day precise weighing method. Fasting blood was tested for riboflavin (erythrocyte glutathione reductase activity coefficient), thiamine (erythrocyte transketolase activity), retinol (fluorimetry) and folic acid status. Alcohol contributed on average 12 per cent of total energy intake in men, and 6 per cent in women. Forty-eight per cent of males and 39 per cent of females were classified as heavy drinkers (HD) with 48 and 28 g/d average alcohol intakes respectively. There was a general tendency for women to add alcohol to their habitual diet, as revealed by the positive correlation between total energy intake and alcohol intake. The higher energy intakes of HD women were also reflected in their higher body weights...
Oxidative stress is one of the most significant risk factors for degenerative disease. Dietary ha... more Oxidative stress is one of the most significant risk factors for degenerative disease. Dietary habits can play a key role in regulating the redox status of human plasma, improving the defense against oxidative damage. Oxidative stress represents an imbalance between humans’ protective molecules, the antioxidants, and molecules able to damage all sorts of cellular components, the free radicals. An inadequate intake of antioxidant nutrients may compromise antioxidant potential, thus compounding overall oxidative stress. The levels of dietary antioxidants in human tissues are strictly related to the amount and food composition of the diet and to their bioavailability, highlighting the importance of interindividual genetic variation. A well-balanced overall dietary pattern and a healthy lifestyle contribute to a higher quality of life, and although new epidemiological and intervention clinical trials could improve our knowledge of the role of antioxidant status in health and disease, the Mediterranean diet seems to be a daily recommended diet for a healthy lifestyle.
There is mounting evidence emphasizing the importance of intracellular antioxidant levels for mai... more There is mounting evidence emphasizing the importance of intracellular antioxidant levels for maintenance of the immune function. The flavonoid quercetin, a natural antioxidant, has been shown to modulate enzymes involved in the regulation of the inflammatory response. However, up to now, there have been no studies describing quercetin levels in cells of the immune system. A gradient reversed-phase HPLC technique
Endocrine, metabolic & immune disorders, Mar 1, 2023
Background: The adipose tissue influences by an extensive crosstalk at the local and systemic lev... more Background: The adipose tissue influences by an extensive crosstalk at the local and systemic level the energy balance, including storage, mobilization, and utilization at both central and peripheral sites in response to specific external stimuli or metabolic changes. The balance between energy intake and expenditure is a delicate equilibrium among multifactorial aspects ranging from genetic to environmental influences. Aim: The evidence from several recently published papers dealing with the topic of the beneficial health effects of micronutrient and plant bioactive compounds on obesity and/or comorbidities has been reported in this paper. Methodology: MEDLINE database (PubMed database; National Library of Medicine, Bethesda, MD and Google Scholar) was searched by combining the terms of specific micronutrients and/or plant bioactive compounds associated with obesity and related comorbidities. All English language manuscripts published between 2005 and 2021 in the MEDLINE database were searched, selected, and reviewed here. Conclusion: People do not consume single food or ingredients but global composite diets; thus, the evaluation of mechanisms of action, efficacy and safety of vitamins and mineral and natural bioactive compounds is still a challenge in research on nutrition and food supplements.
The conversion of a conventional farm to the methods of the organic farming is a very critical st... more The conversion of a conventional farm to the methods of the organic farming is a very critical stage of technical and economical investment. From an agronomical point of view, usually the conversion needs a very different length of time with respect to that set by the regulation, because the organic farming is based on the soil fertility and, in general, on the preservation at the equilibrium of the farm’s ecosystem. These elements affect time and method of the conversions that, although based on clear principles, can require different interventions and solutions and give different results in different times depending on the starting conditions of fertility, farm organization, operating possibilities and knowledge. A research project has been funded by the Lazio Region (central Italy) into the Interregional Programme Agriculture Quality with the general objective to monitor the soil characteristics and biodiversity, the quality of the products as well as to study the economical aspe...
The interrelationship between habitual alcohol consumption, dietary intakes and vitamin status wa... more The interrelationship between habitual alcohol consumption, dietary intakes and vitamin status was examined in 393 elderly subjects (188 men, 205 women, age range 65-90 years) resident in seven retirement homes throughout Italy. Individual food intake was assessed by the 7-day precise weighing method. Fasting blood was tested for riboflavin (erythrocyte glutathione reductase activity coefficient), thiamine (erythrocyte transketolase activity), retinol (fluorimetry) and folic acid status. Alcohol contributed on average 12 per cent of total energy intake in men, and 6 per cent in women. Forty-eight per cent of males and 39 per cent of females were classified as heavy drinkers (HD) with 48 and 28 g/d average alcohol intakes respectively. There was a general tendency for women to add alcohol to their habitual diet, as revealed by the positive correlation between total energy intake and alcohol intake. The higher energy intakes of HD women were also reflected in their higher body weights...
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