Cystic hygroma (CH) is a lymphatic malformation occurring different parts of fetal body, typicall... more Cystic hygroma (CH) is a lymphatic malformation occurring different parts of fetal body, typically in the region of the fetal neck and axillary, abdominal wall, mediastinal, inguinal and retroperitoneal areas. CH has been associated with fetal aneuploidy, hydrops fetalis, structural malformations and intrauterine fetal death. A 24-year-old gravida 1, para 1 was admitted to our hospital at 28 weeks of gestation. Ultrasonographic examination determined 28 weeks of gestation, singleton, alive fetus who had a mass derived from the right axillary region which was extending to the anterior and posterior thoracic wall with fluid-filled cavities about 12 cm in size. There was no evidence of intrathorasic or intraabdominal extension of mass. Cordocentesis was performed and karyotype examination was normal 46 XY. The fetal demise was found after the first visit. The patient was delivered vaginally after labor induction with oxytocin infusion. The fetal autopsy confirmed the diagnosis of CH. T...
Servikal kanser, gebelikle en sik iliskili kanser olup, gebelik sirasinda tani konulan servikal k... more Servikal kanser, gebelikle en sik iliskili kanser olup, gebelik sirasinda tani konulan servikal kanserlerde bir artis tespit edilmektedir. Yaklasik insidansi 2000 gebelikte 1 olgudur ve her 34 servikal kanserli hastadan 1 tanesi gebe kalmaktadir. Gebelikte tani konulmus olan servikal kanser, anne adayi, aile ve dogum hekimi icin ciddi bir sorun teskil etmektedir. Gecmiste 20. gestasyonel haftadan once tespit edilen servikal kanser olgularinda, tedavinin hemen baslatilabilmesi icin gebeligin terminasyonu onerilmekteydi. Son yillarda, gebeligin servikal kanserin progresyonunu arttirmadigi ve fetus viabilite kazanana kadar beklenebilecegi gorusu agirlik kazanmistir. Boyle bir durumda aile gerek maternal ve gerekse fetal riskler acilarindan bilgilendirilmelidir. Gunumuzdeki tedavi yaklasiminda, hem maternal, hem fetal durum dikkate alinmakta; klinik evre, lezyonun buyuklugu ve gestasyonel hafta birlikte degerlendirilmektedir. Calismamizda, gebeligin 22. haftasinda tespit edilen bir serv...
We aimed to develop a new scale for evaluating risks and preventive measures for in-hospital fall... more We aimed to develop a new scale for evaluating risks and preventive measures for in-hospital falls of newborn infants, from admission to discharge of the expectant mother. Our study was prepared in accordance with Failure Modes and Effects Analysis criteria. The risks and preventive measures for in-hospital falls of newborns were determined. Risk Priority Numbers (RPNs) were determined by multiplication of the scores of severity, probability of occurrence, and probability of detection. Analyses showed that risks having the highest RPNs were the mother with epidural anesthesia (RPN: 350 point), holding of the baby at the moment of delivery (RPN: 240), and transportation of baby right after delivery (RPN: 240). A reduction was detected in all RPNs after the application of preventive measures. Our risk model can function as a guide for obstetric clinics that need to form strategies to prevent newborn falls.
Cancer complicates approximately 0.1% of all pregnancies. Primary tracheal carcinoma is one of ve... more Cancer complicates approximately 0.1% of all pregnancies. Primary tracheal carcinoma is one of very rarely seen tumors and the rate of its being seen makes up approximately % 0.2 of all tumors of respiratory tract. The patient, 28 years old, who has 28-weeks-pregnant, was diagnosed with primary tracheal adenocystic carcinoma. Patient was made operation as thoracotomy and tracheal tumor was removed at the 28th week of pregnancy. Patient was delivered with sectio abdominale at the 39th week of pregnancy. Primary tracheal adenocystic carcinoma is very rarely seen tumors and it is the first tracheal ACC with pregnancy case in literature to have been detected and surgically treated during pregnancy. We discussed primary tracheal adenocystic carcinoma and tracheal tumors during pregnancy with literature.
The aim of this study was to investigate malignancy potential in endometrial hyperplasias and ass... more The aim of this study was to investigate malignancy potential in endometrial hyperplasias and association with PCNA and Ki-67. Hysterectomy or probe curettage materials of 62 patients (20 simple hyperplasias (SH), six SH with atypical changes, five complex hyperplasias (CH), 11 CH with atypical changes, ten proliferative endometrium (PE) and ten secretory endometrium) were included in our study. Immunohistochemical staining for PCNA and Ki-67 protein was performed on formalinfixed and paraffin-embedded tissue samples. Immunoreactivity of PCNA was found to be significantly higher in atypical CH as compared to all other groups (p < 0.05). Also immunoreactivity of PCNA was significantly lower in SH as compared to atypical CH, and PE (p < 0.05). Average values showed that Ki-67 immunoreactivity is highest for atypical CH, and PE. Immunoreactivity of Ki-67 was found to be significantly higher in atypical CH as compared to other groups except PE (p < 0.05). PCNA immunoreactivity ...
Cystic hygroma (CH) is a lymphatic malformation occurring different parts of fetal body, typicall... more Cystic hygroma (CH) is a lymphatic malformation occurring different parts of fetal body, typically in the region of the fetal neck and axillary, abdominal wall, mediastinal, inguinal and retroperitoneal areas. CH has been associated with fetal aneuploidy, hydrops fetalis, structural malformations and intrauterine fetal death. A 24-year-old gravida 1, para 1 was admitted to our hospital at 28 weeks of gestation. Ultrasonographic examination determined 28 weeks of gestation, singleton, alive fetus who had a mass derived from the right axillary region which was extending to the anterior and posterior thoracic wall with fluid-filled cavities about 12 cm in size. There was no evidence of intrathorasic or intraabdominal extension of mass. Cordocentesis was performed and karyotype examination was normal 46 XY. The fetal demise was found after the first visit. The patient was delivered vaginally after labor induction with oxytocin infusion. The fetal autopsy confirmed the diagnosis of CH. T...
Servikal kanser, gebelikle en sik iliskili kanser olup, gebelik sirasinda tani konulan servikal k... more Servikal kanser, gebelikle en sik iliskili kanser olup, gebelik sirasinda tani konulan servikal kanserlerde bir artis tespit edilmektedir. Yaklasik insidansi 2000 gebelikte 1 olgudur ve her 34 servikal kanserli hastadan 1 tanesi gebe kalmaktadir. Gebelikte tani konulmus olan servikal kanser, anne adayi, aile ve dogum hekimi icin ciddi bir sorun teskil etmektedir. Gecmiste 20. gestasyonel haftadan once tespit edilen servikal kanser olgularinda, tedavinin hemen baslatilabilmesi icin gebeligin terminasyonu onerilmekteydi. Son yillarda, gebeligin servikal kanserin progresyonunu arttirmadigi ve fetus viabilite kazanana kadar beklenebilecegi gorusu agirlik kazanmistir. Boyle bir durumda aile gerek maternal ve gerekse fetal riskler acilarindan bilgilendirilmelidir. Gunumuzdeki tedavi yaklasiminda, hem maternal, hem fetal durum dikkate alinmakta; klinik evre, lezyonun buyuklugu ve gestasyonel hafta birlikte degerlendirilmektedir. Calismamizda, gebeligin 22. haftasinda tespit edilen bir serv...
We aimed to develop a new scale for evaluating risks and preventive measures for in-hospital fall... more We aimed to develop a new scale for evaluating risks and preventive measures for in-hospital falls of newborn infants, from admission to discharge of the expectant mother. Our study was prepared in accordance with Failure Modes and Effects Analysis criteria. The risks and preventive measures for in-hospital falls of newborns were determined. Risk Priority Numbers (RPNs) were determined by multiplication of the scores of severity, probability of occurrence, and probability of detection. Analyses showed that risks having the highest RPNs were the mother with epidural anesthesia (RPN: 350 point), holding of the baby at the moment of delivery (RPN: 240), and transportation of baby right after delivery (RPN: 240). A reduction was detected in all RPNs after the application of preventive measures. Our risk model can function as a guide for obstetric clinics that need to form strategies to prevent newborn falls.
Cancer complicates approximately 0.1% of all pregnancies. Primary tracheal carcinoma is one of ve... more Cancer complicates approximately 0.1% of all pregnancies. Primary tracheal carcinoma is one of very rarely seen tumors and the rate of its being seen makes up approximately % 0.2 of all tumors of respiratory tract. The patient, 28 years old, who has 28-weeks-pregnant, was diagnosed with primary tracheal adenocystic carcinoma. Patient was made operation as thoracotomy and tracheal tumor was removed at the 28th week of pregnancy. Patient was delivered with sectio abdominale at the 39th week of pregnancy. Primary tracheal adenocystic carcinoma is very rarely seen tumors and it is the first tracheal ACC with pregnancy case in literature to have been detected and surgically treated during pregnancy. We discussed primary tracheal adenocystic carcinoma and tracheal tumors during pregnancy with literature.
The aim of this study was to investigate malignancy potential in endometrial hyperplasias and ass... more The aim of this study was to investigate malignancy potential in endometrial hyperplasias and association with PCNA and Ki-67. Hysterectomy or probe curettage materials of 62 patients (20 simple hyperplasias (SH), six SH with atypical changes, five complex hyperplasias (CH), 11 CH with atypical changes, ten proliferative endometrium (PE) and ten secretory endometrium) were included in our study. Immunohistochemical staining for PCNA and Ki-67 protein was performed on formalinfixed and paraffin-embedded tissue samples. Immunoreactivity of PCNA was found to be significantly higher in atypical CH as compared to all other groups (p < 0.05). Also immunoreactivity of PCNA was significantly lower in SH as compared to atypical CH, and PE (p < 0.05). Average values showed that Ki-67 immunoreactivity is highest for atypical CH, and PE. Immunoreactivity of Ki-67 was found to be significantly higher in atypical CH as compared to other groups except PE (p < 0.05). PCNA immunoreactivity ...
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