Both the macro- and microvascular complications adversely affect the life quality of patients wit... more Both the macro- and microvascular complications adversely affect the life quality of patients with diabetes and have been the leading cause of mortality and morbidity in this population. With the advancement of technologies in biomedical research, we have gained a great deal of understanding of the mechanisms underlying these complications. While euglycemic control still remains the best strategy, it is often difficult to maintain at a level that can completely prevent the vascular complications. Therefore, it is necessary to use the processes leading to vascular dysfunction as a framework for designing novel molecular therapeutic targets. Several of the mechanisms by which diabetes induces vascular complications include increased flux through the polyol pathway, increased oxidative stress, activation of protein kinase C (PKC), vascular inflammation, and abnormal expression and actions of cytokines in the vasculature. Many of the therapies that target these pathways have proven successful in experimental models of diabetic complications. However, clinical studies using these treatments have mainly yielded inconclusive results. The pathogenesis of diabetic vascular complications and results from animal studies and key clinical studies are reviewed here.
To evaluate the effect of intravitreal ranibizumab in patients with leaking disciform scars. In t... more To evaluate the effect of intravitreal ranibizumab in patients with leaking disciform scars. In this retrospective case series, 31 eyes received one or two ranibizumab injections for treatment of choroidal neovascularization. Visual acuity, central retinal thickness, and macular volume were measured prior to injection and at 1-month follow-up. After one injection (n = 31), mean optical coherence tomography (OCT) central foveal thickness decreased from 317 to 242 microm (P = .00016). Mean OCT macular volume decreased from 7.89 to 6.80 mm3 (P = .00019). After two injections (n = 12), mean OCT central foveal thickness decreased from 310 to 248 microm following the second injection (P = .04). Mean OCT macular volume decreased from 7.80 to 6.43 mm3 at 1-month follow-up after a second injection (P = .006). There was no significant change in visual acuity after injections. In the short-term, ranibizumab decreases the leakage associated with choroidal neovascularization in chronic macular degeneration.
2008 International Conference on Computer and Communication Engineering, 2008
The recognition process depends on the how features are extracted. There are several ways for fea... more The recognition process depends on the how features are extracted. There are several ways for feature extraction but the most important is to extract the most effective features and can distinct between patterns. In this research, an approach is proposed to recognize Hindi numerals. ...
The Marine Resources Committee deals with issues associated with the largest ecosystem on Earth. ... more The Marine Resources Committee deals with issues associated with the largest ecosystem on Earth. These issues are as diverse as the ocean ecosystem itself. These issues include marine transportation, from cruise ships to lightering vessels, exploration and production of marine ...
This paper is an attempt to study Kamila Shamsie’s Burnt Shadows through the lens of
Homi K. Bha... more This paper is an attempt to study Kamila Shamsie’s Burnt Shadows through the lens of Homi K. Bhabha’s concepts of ‘mimicry’,‘ambivalence’ and ‘in-betweenness’. The entire postcolonial literature exhibits a kind of cultural hybridity that gives birth to a confused identity of natives .In Shamsie’s Burnt Shadows this aspect of mimicry covers the schizophrenic madness of character of Sajjad in particular and of all characters in general . Love-hate relationships, contradictions between ‘self’ and ‘other’ native-alien clash of cultures, hybridity, creolisation, nostalgia, mimicking tendency, sense of alienation and ultimate disillusionment prevail throughout the novel in one way or the other. Here, the paper discusses the relevance of Bhabha’s perception to understand the typical postcolonial ‘halfness’ which gets a fair handling in the hands of Shamsie. The natives try to mimic and adopt the invader’s culture in order to get acceptance but treated as others and inferiors. In frustration, they espouse extremist ideas and assume extreme shades of indigenous identity. This article will explore the issues of mimicry and identity through the analysis of the novel in the light of Postcolonial critical approaches.
Both the macro- and microvascular complications adversely affect the life quality of patients wit... more Both the macro- and microvascular complications adversely affect the life quality of patients with diabetes and have been the leading cause of mortality and morbidity in this population. With the advancement of technologies in biomedical research, we have gained a great deal of understanding of the mechanisms underlying these complications. While euglycemic control still remains the best strategy, it is often difficult to maintain at a level that can completely prevent the vascular complications. Therefore, it is necessary to use the processes leading to vascular dysfunction as a framework for designing novel molecular therapeutic targets. Several of the mechanisms by which diabetes induces vascular complications include increased flux through the polyol pathway, increased oxidative stress, activation of protein kinase C (PKC), vascular inflammation, and abnormal expression and actions of cytokines in the vasculature. Many of the therapies that target these pathways have proven successful in experimental models of diabetic complications. However, clinical studies using these treatments have mainly yielded inconclusive results. The pathogenesis of diabetic vascular complications and results from animal studies and key clinical studies are reviewed here.
To evaluate the effect of intravitreal ranibizumab in patients with leaking disciform scars. In t... more To evaluate the effect of intravitreal ranibizumab in patients with leaking disciform scars. In this retrospective case series, 31 eyes received one or two ranibizumab injections for treatment of choroidal neovascularization. Visual acuity, central retinal thickness, and macular volume were measured prior to injection and at 1-month follow-up. After one injection (n = 31), mean optical coherence tomography (OCT) central foveal thickness decreased from 317 to 242 microm (P = .00016). Mean OCT macular volume decreased from 7.89 to 6.80 mm3 (P = .00019). After two injections (n = 12), mean OCT central foveal thickness decreased from 310 to 248 microm following the second injection (P = .04). Mean OCT macular volume decreased from 7.80 to 6.43 mm3 at 1-month follow-up after a second injection (P = .006). There was no significant change in visual acuity after injections. In the short-term, ranibizumab decreases the leakage associated with choroidal neovascularization in chronic macular degeneration.
2008 International Conference on Computer and Communication Engineering, 2008
The recognition process depends on the how features are extracted. There are several ways for fea... more The recognition process depends on the how features are extracted. There are several ways for feature extraction but the most important is to extract the most effective features and can distinct between patterns. In this research, an approach is proposed to recognize Hindi numerals. ...
The Marine Resources Committee deals with issues associated with the largest ecosystem on Earth. ... more The Marine Resources Committee deals with issues associated with the largest ecosystem on Earth. These issues are as diverse as the ocean ecosystem itself. These issues include marine transportation, from cruise ships to lightering vessels, exploration and production of marine ...
This paper is an attempt to study Kamila Shamsie’s Burnt Shadows through the lens of
Homi K. Bha... more This paper is an attempt to study Kamila Shamsie’s Burnt Shadows through the lens of Homi K. Bhabha’s concepts of ‘mimicry’,‘ambivalence’ and ‘in-betweenness’. The entire postcolonial literature exhibits a kind of cultural hybridity that gives birth to a confused identity of natives .In Shamsie’s Burnt Shadows this aspect of mimicry covers the schizophrenic madness of character of Sajjad in particular and of all characters in general . Love-hate relationships, contradictions between ‘self’ and ‘other’ native-alien clash of cultures, hybridity, creolisation, nostalgia, mimicking tendency, sense of alienation and ultimate disillusionment prevail throughout the novel in one way or the other. Here, the paper discusses the relevance of Bhabha’s perception to understand the typical postcolonial ‘halfness’ which gets a fair handling in the hands of Shamsie. The natives try to mimic and adopt the invader’s culture in order to get acceptance but treated as others and inferiors. In frustration, they espouse extremist ideas and assume extreme shades of indigenous identity. This article will explore the issues of mimicry and identity through the analysis of the novel in the light of Postcolonial critical approaches.
Uploads
Papers by Fatima Ahmad
Homi K. Bhabha’s concepts of ‘mimicry’,‘ambivalence’ and ‘in-betweenness’. The entire
postcolonial literature exhibits a kind of cultural hybridity that gives birth to a confused identity of natives .In Shamsie’s Burnt Shadows this aspect of mimicry covers the schizophrenic madness of character of Sajjad in particular and of all characters in general . Love-hate relationships, contradictions between ‘self’ and ‘other’ native-alien clash of cultures, hybridity, creolisation, nostalgia, mimicking tendency, sense of alienation and ultimate disillusionment prevail throughout the novel in one way or the other. Here, the paper discusses the relevance of Bhabha’s perception to understand the typical postcolonial ‘halfness’ which gets a fair handling in the hands of Shamsie. The natives try to mimic and adopt the invader’s culture in order to get acceptance but treated as others and inferiors. In frustration, they espouse extremist ideas and assume extreme shades of indigenous identity. This article will explore the issues of mimicry and identity through the analysis of the novel in the light of Postcolonial critical approaches.
Homi K. Bhabha’s concepts of ‘mimicry’,‘ambivalence’ and ‘in-betweenness’. The entire
postcolonial literature exhibits a kind of cultural hybridity that gives birth to a confused identity of natives .In Shamsie’s Burnt Shadows this aspect of mimicry covers the schizophrenic madness of character of Sajjad in particular and of all characters in general . Love-hate relationships, contradictions between ‘self’ and ‘other’ native-alien clash of cultures, hybridity, creolisation, nostalgia, mimicking tendency, sense of alienation and ultimate disillusionment prevail throughout the novel in one way or the other. Here, the paper discusses the relevance of Bhabha’s perception to understand the typical postcolonial ‘halfness’ which gets a fair handling in the hands of Shamsie. The natives try to mimic and adopt the invader’s culture in order to get acceptance but treated as others and inferiors. In frustration, they espouse extremist ideas and assume extreme shades of indigenous identity. This article will explore the issues of mimicry and identity through the analysis of the novel in the light of Postcolonial critical approaches.