Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineerin... more Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineering constructs. The bioprintable materials with cells or other biological parts, which are called bioinks, are arranged layer by layer and make multicellular structures. Not all materials can be printed, and a set of requirements should be met to formulate the appropriate bioink. Poly (ethylene glycol) (PEGDA), as a synthetic polymer, is a promising choice for regenerative medicine applications due to its biocompatibility, ease of crosslinking, and adjustability of its mechanical and chemical properties depending on the application. This review aims to guide and familiarize the reader with the PEGDA‐based bioink as a raw material of the 3D‐bioprinting method, its properties, and applications in soft and hard tissue engineering.
Journal of Materials Science: Materials in Medicine, 2022
Amniotic membrane (AM) is a biological tissue that surrounds the fetus in the mother’s womb. It h... more Amniotic membrane (AM) is a biological tissue that surrounds the fetus in the mother’s womb. It has pluripotent cells, immune modulators, collagen, cytokines with anti-fibrotic and anti-inflammatory effect, matrix proteins, and growth factors. In spite of the biological characteristics, some results have been released in preventing the adhesion on traumatized surfaces. Application of the AM as a scaffold is limited due to its low biomechanical resistance and rapid biodegradation. Therefore, for using the AM during surgery, its modification by different methods such as cross-linking of the membrane collagen is necessary, because the cross-linking is an effective way to reduce the rate of biodegradation of the biological materials. In addition, their cross-linking is likely an efficient way to increase the tensile properties of the material, so that they can be easily handled or sutured. In this regard, various methods related to cross-linking of the AM subsuming the composite materia...
Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineerin... more Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineering constructs. The bioprintable materials with cells or other biological parts, which are called bioinks, are arranged layer by layer and make multicellular structures. Not all materials can be printed, and a set of requirements should be met to formulate the appropriate bioink. Poly (ethylene glycol) (PEGDA), as a synthetic polymer, is a promising choice for regenerative medicine applications due to its biocompatibility, ease of crosslinking, and adjustability of its mechanical and chemical properties depending on the application. This review aims to guide and familiarize the reader with the PEGDA‐based bioink as a raw material of the 3D‐bioprinting method, its properties, and applications in soft and hard tissue engineering.
Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineerin... more Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineering constructs. The bioprintable materials with cells or other biological parts, which are called bioinks, are arranged layer by layer and make multicellular structures. Not all materials can be printed, and a set of requirements should be met to formulate the appropriate bioink. Poly (ethylene glycol) (PEGDA), as a synthetic polymer, is a promising choice for regenerative medicine applications due to its biocompatibility, ease of crosslinking, and adjustability of its mechanical and chemical properties depending on the application. This review aims to guide and familiarize the reader with the PEGDA‐based bioink as a raw material of the 3D‐bioprinting method, its properties, and applications in soft and hard tissue engineering.
Journal of Materials Science: Materials in Medicine, 2022
Amniotic membrane (AM) is a biological tissue that surrounds the fetus in the mother’s womb. It h... more Amniotic membrane (AM) is a biological tissue that surrounds the fetus in the mother’s womb. It has pluripotent cells, immune modulators, collagen, cytokines with anti-fibrotic and anti-inflammatory effect, matrix proteins, and growth factors. In spite of the biological characteristics, some results have been released in preventing the adhesion on traumatized surfaces. Application of the AM as a scaffold is limited due to its low biomechanical resistance and rapid biodegradation. Therefore, for using the AM during surgery, its modification by different methods such as cross-linking of the membrane collagen is necessary, because the cross-linking is an effective way to reduce the rate of biodegradation of the biological materials. In addition, their cross-linking is likely an efficient way to increase the tensile properties of the material, so that they can be easily handled or sutured. In this regard, various methods related to cross-linking of the AM subsuming the composite materia...
Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineerin... more Three‐dimensional (3D) bioprinting is a promising method for the fabrication of tissue engineering constructs. The bioprintable materials with cells or other biological parts, which are called bioinks, are arranged layer by layer and make multicellular structures. Not all materials can be printed, and a set of requirements should be met to formulate the appropriate bioink. Poly (ethylene glycol) (PEGDA), as a synthetic polymer, is a promising choice for regenerative medicine applications due to its biocompatibility, ease of crosslinking, and adjustability of its mechanical and chemical properties depending on the application. This review aims to guide and familiarize the reader with the PEGDA‐based bioink as a raw material of the 3D‐bioprinting method, its properties, and applications in soft and hard tissue engineering.
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