Keto group of cyano pyridine moiety have been treated with various aromatic aldehydes to give cor... more Keto group of cyano pyridine moiety have been treated with various aromatic aldehydes to give corresponding chalcones. The Chalcones have been reacted with urea and thiourea to get corresponding novel oxopyrimidines and thiopyrimidines, the structure of all newly synthesized compounds were confirmed by spectral analysis. The synthesized compounds were evaluated for their antimicrobial activity. All the synthesized pyrimidine compounds have show good to moderate antimicrobial activity.
Since its commencement in the last decade there were quite a few new technologies, new routes and... more Since its commencement in the last decade there were quite a few new technologies, new routes and new approaches that were developed in synthetic organic chemistry viz. Microwave Assisted Organic Synthesis, Aqua Mediated Organic Synthesis, Synthesis using different solvents like Ionic Liquids as well as some super critical solvents etc. which brought about a kind of revolution and also a shift in the mind set of common people as well as a shift of focus among the scientific fraternity. As expected, green chemistry has grown into a significant internationally engaged focus area within chemistry. So, we have tried to developed a new route by greener way as describe in the book.
Keto group of cyano pyridine moiety have been treated with various aromatic aldehydes to give cor... more Keto group of cyano pyridine moiety have been treated with various aromatic aldehydes to give corresponding chalcones. The Chalcones have been reacted with urea and thiourea to get corresponding novel oxopyrimidines and thiopyrimidines, the structure of all newly synthesized compounds were confirmed by spectral analysis. The synthesized compounds were evaluated for their antimicrobial activity. All the synthesized pyrimidine compounds have show good to moderate antimicrobial activity.
Since its commencement in the last decade there were quite a few new technologies, new routes and... more Since its commencement in the last decade there were quite a few new technologies, new routes and new approaches that were developed in synthetic organic chemistry viz. Microwave Assisted Organic Synthesis, Aqua Mediated Organic Synthesis, Synthesis using different solvents like Ionic Liquids as well as some super critical solvents etc. which brought about a kind of revolution and also a shift in the mind set of common people as well as a shift of focus among the scientific fraternity. As expected, green chemistry has grown into a significant internationally engaged focus area within chemistry. So, we have tried to developed a new route by greener way as describe in the book.
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