Introduction: The contribution of renal biopsy is of major importance in many paediatrics renal d... more Introduction: The contribution of renal biopsy is of major importance in many paediatrics renal diseases. This prospective study analysed the clinic-pathological spectrum of the biopsied cases, complications related to renal biopsy and its effect on management. Methods: USG guided percutaneous renal biopsy was performed in indicated children. Laboratory findings, complications of the procedure, histological diagnosis and its effect on management were obtained from all patients who underwent renal biopsy from April 2019 to March 2020. The data were finally analysed using descriptive statistics. Results: Total 50 cases were enrolled during the study period. There were 24 males and 26 females with age range from two to 16 years. The common indications for biopsy were acute nephritic syndrome (25 cases), including both primary glomerulonephritis (11 cases) and secondary glomerulonephritis (14 cases), of which lupus nephritis contributed (11/25) cases, followed by atypical/ steroid resis...
Background Tuberculosis (TB) and severe acute malnutrition (SAM) are important causes of morbidit... more Background Tuberculosis (TB) and severe acute malnutrition (SAM) are important causes of morbidity and mortality in children in the developing World. Malnutrition mainly affects cell mediated immunity (CMI) and CMI is the principal host defense against tuberculosis. Hence, there is possibility that children with SAM may have tuberculosis, and often it may be a hidden entity. Further, Children with SAM and TB are 40% more likely to die than children with SAM and without TB. Children with SAM rarely come to health care settings with complaint of under nutrition rather they present for some other illness. For these reasons, this study intends to seek for TB among children with SAM and look into the common presenting complaints. Methods All cases of SAM meeting the inclusion criteria were evaluated with mantoux, chest x-ray, gastric aspirate/sputum analysis and gene xpert for diagnosis of TB. Other relevant investigations for diagnosis of TB were also sent as per the clinical scenario. ...
Birth asphyxia is defined as the presence of hypoxia, hypercapnia, and acidosis leading the newbo... more Birth asphyxia is defined as the presence of hypoxia, hypercapnia, and acidosis leading the newborn to systemic disturbances probably electrolyte disturbance also. Knowledge of these electrolyte disturbances is very valuable as it can be an important parameter affecting perinatal morbidity, mortality and ongoing management. Serum sodium, potassium and ionized calcium of asphyxiated term newborn were sent within one hour of birth as per the inclusion criteria. Statistical comparison of mean values of different electrolytes between different groups of perinatal asphyxia was performed by ANOVA test for parametric data and significant data were further analyzed using post hoc test. Bivariate analysis was done to determine the correlations between Apgar score at 5 min and serum electrolytes. Pearson test was used to calculate the correlation coefficient. Box plot was used to show the median and quartile between serum electrolytes and Apgar score at 5 min. The mean values of sodium for mi...
Introduction: The contribution of renal biopsy is of major importance in many paediatrics renal d... more Introduction: The contribution of renal biopsy is of major importance in many paediatrics renal diseases. This prospective study analysed the clinic-pathological spectrum of the biopsied cases, complications related to renal biopsy and its effect on management. Methods: USG guided percutaneous renal biopsy was performed in indicated children. Laboratory findings, complications of the procedure, histological diagnosis and its effect on management were obtained from all patients who underwent renal biopsy from April 2019 to March 2020. The data were finally analysed using descriptive statistics. Results: Total 50 cases were enrolled during the study period. There were 24 males and 26 females with age range from two to 16 years. The common indications for biopsy were acute nephritic syndrome (25 cases), including both primary glomerulonephritis (11 cases) and secondary glomerulonephritis (14 cases), of which lupus nephritis contributed (11/25) cases, followed by atypical/ steroid resis...
Background Tuberculosis (TB) and severe acute malnutrition (SAM) are important causes of morbidit... more Background Tuberculosis (TB) and severe acute malnutrition (SAM) are important causes of morbidity and mortality in children in the developing World. Malnutrition mainly affects cell mediated immunity (CMI) and CMI is the principal host defense against tuberculosis. Hence, there is possibility that children with SAM may have tuberculosis, and often it may be a hidden entity. Further, Children with SAM and TB are 40% more likely to die than children with SAM and without TB. Children with SAM rarely come to health care settings with complaint of under nutrition rather they present for some other illness. For these reasons, this study intends to seek for TB among children with SAM and look into the common presenting complaints. Methods All cases of SAM meeting the inclusion criteria were evaluated with mantoux, chest x-ray, gastric aspirate/sputum analysis and gene xpert for diagnosis of TB. Other relevant investigations for diagnosis of TB were also sent as per the clinical scenario. ...
Birth asphyxia is defined as the presence of hypoxia, hypercapnia, and acidosis leading the newbo... more Birth asphyxia is defined as the presence of hypoxia, hypercapnia, and acidosis leading the newborn to systemic disturbances probably electrolyte disturbance also. Knowledge of these electrolyte disturbances is very valuable as it can be an important parameter affecting perinatal morbidity, mortality and ongoing management. Serum sodium, potassium and ionized calcium of asphyxiated term newborn were sent within one hour of birth as per the inclusion criteria. Statistical comparison of mean values of different electrolytes between different groups of perinatal asphyxia was performed by ANOVA test for parametric data and significant data were further analyzed using post hoc test. Bivariate analysis was done to determine the correlations between Apgar score at 5 min and serum electrolytes. Pearson test was used to calculate the correlation coefficient. Box plot was used to show the median and quartile between serum electrolytes and Apgar score at 5 min. The mean values of sodium for mi...
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