New techniques for the evaluation of specific components of blood pressure waveforms have been sh... more New techniques for the evaluation of specific components of blood pressure waveforms have been shown to have broad applications in cardiology. One of the more useful parameters of pressure wave analysis is the augmentation index (AI), which measures the interaction of the forward pressure wave with reflected waves from the distal circulation. Analysis of AI and associated wave functions show differences related to cardiac risk, the presence of disease, and the effects of drug administration. The AI can provide useful additional information in the evaluation of high-risk populations and is a useful research tool in evaluating drug and treatment effects. New techniques have allowed AI to become more widely available and current measurements are convenient and reliable.
OBJECTIVE Accurate measurement of blood pressure (BP) is crucial for hypertension management. Acc... more OBJECTIVE Accurate measurement of blood pressure (BP) is crucial for hypertension management. Accuracy of brachial cuff (BCUFF) devices to measure invasive (intra-arterial) BP at the brachial artery (BINV) and aorta (AINV) has never been systematically assessed. This study aimed to determine the: 1) relationship between BINV and AINV; 2) accuracy of BCUFF devices to estimate invasive BP and; 3) accuracy of BCUFF devices to classify BP thresholds. DESIGN AND METHOD Three individual patient meta-analyses (by search of online databases and systematic review supplemented by measurements in a tertiary hospital cardiac catheterization laboratory) were performed to determine: 1) BINV versus AINV BP; 2) BCUFF versus BINV BP and AINV BP and; 3) BCUFF for BP classification versus invasive BP. RESULTS Most subjects (90%) were patients undergoing cardiac catheterization (total N = 3004; mean age 58.7 years, 95%CI [54.0, 63.4], 68% male). As shown in the table: 1) BINV systolic BP (SBP) was sign...
New techniques for the evaluation of specific components of blood pressure waveforms have been sh... more New techniques for the evaluation of specific components of blood pressure waveforms have been shown to have broad applications in cardiology. One of the more useful parameters of pressure wave analysis is the augmentation index (AI), which measures the interaction of the forward pressure wave with reflected waves from the distal circulation. Analysis of AI and associated wave functions show differences related to cardiac risk, the presence of disease, and the effects of drug administration. The AI can provide useful additional information in the evaluation of high-risk populations and is a useful research tool in evaluating drug and treatment effects. New techniques have allowed AI to become more widely available and current measurements are convenient and reliable.
OBJECTIVE Accurate measurement of blood pressure (BP) is crucial for hypertension management. Acc... more OBJECTIVE Accurate measurement of blood pressure (BP) is crucial for hypertension management. Accuracy of brachial cuff (BCUFF) devices to measure invasive (intra-arterial) BP at the brachial artery (BINV) and aorta (AINV) has never been systematically assessed. This study aimed to determine the: 1) relationship between BINV and AINV; 2) accuracy of BCUFF devices to estimate invasive BP and; 3) accuracy of BCUFF devices to classify BP thresholds. DESIGN AND METHOD Three individual patient meta-analyses (by search of online databases and systematic review supplemented by measurements in a tertiary hospital cardiac catheterization laboratory) were performed to determine: 1) BINV versus AINV BP; 2) BCUFF versus BINV BP and AINV BP and; 3) BCUFF for BP classification versus invasive BP. RESULTS Most subjects (90%) were patients undergoing cardiac catheterization (total N = 3004; mean age 58.7 years, 95%CI [54.0, 63.4], 68% male). As shown in the table: 1) BINV systolic BP (SBP) was sign...
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Papers by Kenji Takazawa