El Fenomeno de Lucio (FL), probablemente mediado por inmunocomplejos, se caracteriza por una reac... more El Fenomeno de Lucio (FL), probablemente mediado por inmunocomplejos, se caracteriza por una reaccion cutanea necrosante grave que ocurre en pacientes portadores de Lepra no nodular[1]. La literatura revisada muestra inadecuado uso de esta definicion. Muchos autores identifican como Fenomeno de Lucio las reacciones vasculonecroticas que ocurren en formas distintas a la Lepra difusa[2, 9]. Presentamos dos casos clinicos de pacientes con formas difusas de Enfermedad de Hansen que desarrollaron fenomenos vasculonecroticos.
El cancer de piel “es aquel que se forma en los tejidos de la piel”. Existe un incremento vertigi... more El cancer de piel “es aquel que se forma en los tejidos de la piel”. Existe un incremento vertiginoso de los casos de cancer de piel, con una frecuencia que llega a multiplicar por 5 el de canceres de mama o de prostata. La incidencia sigue aumentado debido a la mayor longevidad de la poblacion y a la mejora en la calidad de vida que facilita habitos de ocio con exposicion solar prolongada. El objetivo general fue determinar las caracteristicas epidemiologicas del cancer de piel en pacientes que consultaron en la Catedra de Dermatologia de la Facultad de Ciencias Medicas de la Universidad Nacional de Asuncion, Paraguay durante los anos 2008 al 2011. Se realizo un estudio observacional, descriptivo, de corte transversal, temporalmente retrospectivo en la Catedra de Dermatologia de la Facultad de Ciencias Medicas de la Universidad Nacional de Asuncion, Paraguay entre julio de 2008 a diciembre de 2011. El muestreo fue no probabilistico a conveniencia. El tamano de la muestra fue de 280...
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by vascularthrombosis,... more The antiphospholipid syndrome (APS) is an autoimmune disease characterized by vascularthrombosis, recurrent abortions and persistent elevation of antiphospholipid antibodies. Since its first description in 1983, a wide variety of dermatological manifestations have been associated with this syndrome, most frequently livedo reticularis and skin ulcers. The presence of antiphospholipid antibodies has been described in several diseases such as autoimmune diseases, infections, neoplasms and secondarily to the use of certain drugs. We report the case of a 72-year-old diagnosed with Rheumatoid Arthritis and secondary APS, for its unusual relationship.
Leprosy is a chronic infectious disease with a broad spectrum of clinical manifestations. Lucioph... more Leprosy is a chronic infectious disease with a broad spectrum of clinical manifestations. Luciophenomenon and necrotic erythema nodosum leprosum are two vasculonecrotic reactions that can mimic cutaneous vasculitis in leprosy. Although they can be distinguished through clinical and histopathological features, both are often used as synonyms. Lucio Phenomenon, a severe immunecomplex mediated skin reaction, is a necrotizing skin condition that occurs in patients with non-nodular or diffuse leprosy which occurs in patients with little or no resistance to infection. Vasculonecrotic reactions due to erythema nodosum occur in other forms of leprosy different from the diffuse form. We present the case of 3 patients with lepromatous leprosy who presented vasculonecrotic reactions. The differential diagnosis between Lucio phenomenon and necrotic erythema nodosum leprosum is important since both entities have different treatments. In a patient with cutaneous vasculitic lesions, infectious eti...
Presentamos el caso de una mujer que consultó por severo prurito en párpados superiores e inferio... more Presentamos el caso de una mujer que consultó por severo prurito en párpados superiores e inferiores de ambos ojos y eritema intenso que apareció tras rascado. En la entrevista, la paciente refirió que estas lesiones habían sido producidas por “bichos y gusanos que están en su piel y alrededor de sus ojos”. Los bichos le picaron y la obligaron a rascarse la piel para poder sacarlos”. No se constató infestación parasitaria. El examen psíquico reveló la presencia de ideas delirantes de infestación parasitaria, por lo que se configuró el diagnóstico de Delirio de Parasitosis. Este trastorno, conocido también como Síndrome de Ekbom, se encuentra clasificado dentro de las afecciones cutáneas estrictamente psiquiátricas de Caroline Koblenzer, en las que el paciente presenta una idea delirante de estar infestado por insectos, gusanos o piojos que habitan y dañan su piel. En la mayoría de los casos, el pronóstico es favorable y el trastorno tiene buena respuesta a la risperidona siempre y c...
International Journal of Culture and Mental Health, 2016
ABSTRACT Psychological wellbeing is associated with variables of living among all human beings an... more ABSTRACT Psychological wellbeing is associated with variables of living among all human beings and has important implications for college students. Their coping strategies will vary as will their responses, depending upon their self-esteem and self-efficacy, personality patterns, mental health, financial development and lifestyle. There is little research on subjective psychological wellbeing among college students. This study describes 560 self-report completed questionnaires from 10 medical students. Subjective psychological wellbeing was analyzed employing the questionnaire Versión Adaptada del Método de Muestreo de Experiencia (Adapted Version of the Experience Sampling Method). The assessed conditions were ‘flow’ (perceived skills and challenges are higher and balanced), ‘boredom’ (perceived skills higher than challenges), ‘anxiety’ (perceived challenges higher than skills) and ‘apathy’ (perceived skills and challenges both lower and balanced). We found that the mean score of the perceived challenges was 4.23±2.42, whereas the mean score of perceived skills was higher, at 5.73±2.08. The fact that the ‘perceived skills’ score was higher than ‘perceived challenges’ score meets criteria for a ‘boredom’ condition. It is known that boredom may be associated to drug abuse, delinquency and academic failure among young subjects. Further studies are needed in order to establish strategies to improve motivation and spirit of challenge.
El Fenomeno de Lucio (FL), probablemente mediado por inmunocomplejos, se caracteriza por una reac... more El Fenomeno de Lucio (FL), probablemente mediado por inmunocomplejos, se caracteriza por una reaccion cutanea necrosante grave que ocurre en pacientes portadores de Lepra no nodular[1]. La literatura revisada muestra inadecuado uso de esta definicion. Muchos autores identifican como Fenomeno de Lucio las reacciones vasculonecroticas que ocurren en formas distintas a la Lepra difusa[2, 9]. Presentamos dos casos clinicos de pacientes con formas difusas de Enfermedad de Hansen que desarrollaron fenomenos vasculonecroticos.
El cancer de piel “es aquel que se forma en los tejidos de la piel”. Existe un incremento vertigi... more El cancer de piel “es aquel que se forma en los tejidos de la piel”. Existe un incremento vertiginoso de los casos de cancer de piel, con una frecuencia que llega a multiplicar por 5 el de canceres de mama o de prostata. La incidencia sigue aumentado debido a la mayor longevidad de la poblacion y a la mejora en la calidad de vida que facilita habitos de ocio con exposicion solar prolongada. El objetivo general fue determinar las caracteristicas epidemiologicas del cancer de piel en pacientes que consultaron en la Catedra de Dermatologia de la Facultad de Ciencias Medicas de la Universidad Nacional de Asuncion, Paraguay durante los anos 2008 al 2011. Se realizo un estudio observacional, descriptivo, de corte transversal, temporalmente retrospectivo en la Catedra de Dermatologia de la Facultad de Ciencias Medicas de la Universidad Nacional de Asuncion, Paraguay entre julio de 2008 a diciembre de 2011. El muestreo fue no probabilistico a conveniencia. El tamano de la muestra fue de 280...
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by vascularthrombosis,... more The antiphospholipid syndrome (APS) is an autoimmune disease characterized by vascularthrombosis, recurrent abortions and persistent elevation of antiphospholipid antibodies. Since its first description in 1983, a wide variety of dermatological manifestations have been associated with this syndrome, most frequently livedo reticularis and skin ulcers. The presence of antiphospholipid antibodies has been described in several diseases such as autoimmune diseases, infections, neoplasms and secondarily to the use of certain drugs. We report the case of a 72-year-old diagnosed with Rheumatoid Arthritis and secondary APS, for its unusual relationship.
Leprosy is a chronic infectious disease with a broad spectrum of clinical manifestations. Lucioph... more Leprosy is a chronic infectious disease with a broad spectrum of clinical manifestations. Luciophenomenon and necrotic erythema nodosum leprosum are two vasculonecrotic reactions that can mimic cutaneous vasculitis in leprosy. Although they can be distinguished through clinical and histopathological features, both are often used as synonyms. Lucio Phenomenon, a severe immunecomplex mediated skin reaction, is a necrotizing skin condition that occurs in patients with non-nodular or diffuse leprosy which occurs in patients with little or no resistance to infection. Vasculonecrotic reactions due to erythema nodosum occur in other forms of leprosy different from the diffuse form. We present the case of 3 patients with lepromatous leprosy who presented vasculonecrotic reactions. The differential diagnosis between Lucio phenomenon and necrotic erythema nodosum leprosum is important since both entities have different treatments. In a patient with cutaneous vasculitic lesions, infectious eti...
Presentamos el caso de una mujer que consultó por severo prurito en párpados superiores e inferio... more Presentamos el caso de una mujer que consultó por severo prurito en párpados superiores e inferiores de ambos ojos y eritema intenso que apareció tras rascado. En la entrevista, la paciente refirió que estas lesiones habían sido producidas por “bichos y gusanos que están en su piel y alrededor de sus ojos”. Los bichos le picaron y la obligaron a rascarse la piel para poder sacarlos”. No se constató infestación parasitaria. El examen psíquico reveló la presencia de ideas delirantes de infestación parasitaria, por lo que se configuró el diagnóstico de Delirio de Parasitosis. Este trastorno, conocido también como Síndrome de Ekbom, se encuentra clasificado dentro de las afecciones cutáneas estrictamente psiquiátricas de Caroline Koblenzer, en las que el paciente presenta una idea delirante de estar infestado por insectos, gusanos o piojos que habitan y dañan su piel. En la mayoría de los casos, el pronóstico es favorable y el trastorno tiene buena respuesta a la risperidona siempre y c...
International Journal of Culture and Mental Health, 2016
ABSTRACT Psychological wellbeing is associated with variables of living among all human beings an... more ABSTRACT Psychological wellbeing is associated with variables of living among all human beings and has important implications for college students. Their coping strategies will vary as will their responses, depending upon their self-esteem and self-efficacy, personality patterns, mental health, financial development and lifestyle. There is little research on subjective psychological wellbeing among college students. This study describes 560 self-report completed questionnaires from 10 medical students. Subjective psychological wellbeing was analyzed employing the questionnaire Versión Adaptada del Método de Muestreo de Experiencia (Adapted Version of the Experience Sampling Method). The assessed conditions were ‘flow’ (perceived skills and challenges are higher and balanced), ‘boredom’ (perceived skills higher than challenges), ‘anxiety’ (perceived challenges higher than skills) and ‘apathy’ (perceived skills and challenges both lower and balanced). We found that the mean score of the perceived challenges was 4.23±2.42, whereas the mean score of perceived skills was higher, at 5.73±2.08. The fact that the ‘perceived skills’ score was higher than ‘perceived challenges’ score meets criteria for a ‘boredom’ condition. It is known that boredom may be associated to drug abuse, delinquency and academic failure among young subjects. Further studies are needed in order to establish strategies to improve motivation and spirit of challenge.
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Papers by Lourdes Bolla