Actas De Las I Jornadas De Jovenes En Investigacion Arqueologica Dialogando Con La Cultura Material Madrid 3 5 De Septiembre De 2008 Vol 1 2008 Isbn 978 84 92539 23 9 Pags 117 122, 2008
This paper summarizes an archaeological survey methodology aimed to contrast and to improve the i... more This paper summarizes an archaeological survey methodology aimed to contrast and to improve the information contained in the Archaeological Inventories about the closest area to “El Casetón de la Era II”, the first enclosure excavated in the North Meseta. The objective is to do the best with a future locational analysis that will bring new knowledge about a kind of sites that are changing many of the previous ideas about the Recent Prehistory in the middle Douro Valley.
Actas De Las Ii Jornadas De Jovenes En Investigacion Arqueologica Jia 09 Vol 2 2011 Isbn 978 84 7956 094 2 Pags 455 462, 2011
This paper summarizes the methodology applied to the study of the prehistoric occupation in the e... more This paper summarizes the methodology applied to the study of the prehistoric occupation in the environment close to the first enclosure excavated in the North Meseta: “El Casetón de la Era II”. The locational analysis was designed from some theoretic questions organized in 3 blocks: orography, visibility and accessibility. Using these questions as a guideline we established concepts as “orographic prominence” or “visual control” with a statistic parameter; besides, we chose evaluation criteria for the hypothesis, working guidelines and the most suitable software. The results stand out because of their analogical and objective nature in contrast of previous studies that express their conclusions in a digital and subjective way. To sum up, it’s a work model suitable for a fragmented archaeological record and for a plain landscape, which can, however, be useful to future researches in other contexts that search in the landscape the habitability decisions of the late societies.
Since 1975 the site of "Las Pozas" has named the Copper Age in ... more Since 1975 the site of "Las Pozas" has named the Copper Age in Spanish Northern Plateau. In the last decade several causewayed enclosures dated to this period have been discovered. This new situation has led us to revise the foundational site using remote sensing techniques. The infrared images have allowed us to distinguish two overlapping enclosures at "Las Pozas": a north one with three interrupted ditches and a southern group composed of two circles. This paper describes the characteristics of both enclosures using as well the information provided by 1979 and 1987 excavations. We believe this discovery certifies that causewayed enclosures were a common feature in the Douro Valley during the Copper Age.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2005
Sonnography and Tc-99m sestamibi scintigraphy are the most requested preoperative imaging tests n... more Sonnography and Tc-99m sestamibi scintigraphy are the most requested preoperative imaging tests nowdays in the surgery of hyperparathyroidism. The aim of our article is to know if Computerized Tomography (CT) and Magnetic Resonance Imaging (MRI) are useful as a location study and in which cases it would be more justified to ask these radiologic techniques. For that we report our results with 29 patients at all diagnosed as hyperparathyroidism (26 primary forms and 3 secondary ones) and operated by our E.N.T. Department later. On 20 of them a cervical CT was asked before the parathyroidectomy and on the rest 9, a MRI with sensitivities of 65% and 88.9% respectively. We think both complementary explorations must not be solicited by routine but they can represent a help in the cases in that sonnography and scintigraphy are not able to show the possible adenoma or hiperplasia, particularly in recurrent hyperparathyroidisms, reinterventions or suspect of parathyroid glands in an atypical location.
Sand flies are recognized as the major vector of canine visceral leishmaniasis. However, in some ... more Sand flies are recognized as the major vector of canine visceral leishmaniasis. However, in some areas of Brazil where sand flies do not occur, this disease is found in humans and dogs. There has been speculation that ticks might play a role in transmission of canine visceral leishmaniasis and the DNA of Leishmania spp. has been reported in whole ticks. We investigated the presence of Leishmania spp. promastigotes in the intestines, ovaries, and salivary glands of Rhipicephalus sanguineus ticks collected from tick-infested dogs in two cities of Brazil. We used 66 dogs that tested positive and 33 that tested negative for Leishmania spp. according to direct cytological examination assays. Ten ticks were collected from each dog and dissected to collect the intestines, ovaries, and salivary glands for immunohistochemistry (IHC) and diagnostic real-time polymerase chain reaction (RT-PCR). IHC results showed Leishmania spp. in 98, 14, and 8 % of the intestines, ovaries, and salivary gland...
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2005
Deep suprasternal infections secondary to cardiac surgery are uncommon but can compromise the lif... more Deep suprasternal infections secondary to cardiac surgery are uncommon but can compromise the life ofthe patient. After a sternotomy it is possible to find late cervico-thoracic abscesses specially in the presence of risk factors. We are reporting the case of a diabetic female of 67 years old with aortocoronary bypass who was diagnosed of suprasternal and neck base abscess in relation to her intervention 11 years later. It was necessary to practice drainage of the collection and wide spectrum antibioticotherapy with good evolution. 4 months after the surgery she was admitted again suffering a thoracic abscess that required treatment by Cardiac Surgery. The clinical follow-up was 3 years and no new recurrences have been detected.
Tick infestation may cause several problems including affecting domestic animal health and reduci... more Tick infestation may cause several problems including affecting domestic animal health and reducing the production of meat and milk, among others. Resistance to several classes of acaricides have been reported, forcing researchers to search for alternative measures, such as vaccines against ticks, to ensure tick control while having no or at least low negative impacts on the environment and public health. However, the current commercially available vaccines in different strains of Rhipicephalus microplus are reported to be of low efficacy. Fortunately, reverse vaccinology approaches have shown positive results in the new generation of vaccines. On this basis, a synthetic peptide from the ATAQ protein, which is present in the gut and Malpighi tubes of R. microplus, was synthesized. The ATAQ proteins were isolated, characterized and sequenced from several species of the genus Rhipicephalus. The alignment showed 93.3% identity among DNA sequences of ATAQs from these species. Because of this, immunization trials with this peptide were conducted on mice, rabbits and cattle to evaluate the humoral immune response and the efficacy against Rhipicephalus sanguineus in addition to R. microplus. Based on recent results, we conclude that reverse vaccinology is a promising approach because it is more accurate and faster than conventional methods in the detection of potential antigens to use in anti-tick vaccines. It is not only applicable against R. microplus but also against tick species that play important roles in spreading other diseases. ATAQ proteins should be considered as the antigen in new trials to develop a multi-antigenic vaccine. Although these peptides behave as hapten and are not able to be recognized by the immune system on its own, using carriers and adjuvants helps its presentation and induces strong immune responses. Furthermore, an efficiency of 35% reduction in overall life cycle parameters was reported for R. microplus (98% for ELISA responder animals) and 47% for R. sanguineus. Although not yet enough to prevent the environment to infestation of ticks, this still constitutes a promising strategy that could be applied to integrated measures on tick control and in new research that develops anti-tick vaccines.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2005
We report the clinical case of a 41 years old male with nasal obstruction of 1 year, epistaxis an... more We report the clinical case of a 41 years old male with nasal obstruction of 1 year, epistaxis and epiphora. The ENT exam showed a bleeding red mass in left nasal fossa and CT joint to IRM revealed a tumoral process on that level and informed about its extension to adyacents structures (cavum, ethmoides, sphenoids and maxillary sinus). The biopsy was positive for cystic adenoid carcinoma. Our patient was operated by paralateronasal rhinotomy with removal of the tumor. One year later we found recurrence on the left orbital floor and maxilar sinus. The Oncology Department informed that it was not possible a treatment with radiotherapy or chemotherapy because the low sensitivity of that lesion those treatment.
Actas De Las I Jornadas De Jovenes En Investigacion Arqueologica Dialogando Con La Cultura Material Madrid 3 5 De Septiembre De 2008 Vol 1 2008 Isbn 978 84 92539 23 9 Pags 117 122, 2008
This paper summarizes an archaeological survey methodology aimed to contrast and to improve the i... more This paper summarizes an archaeological survey methodology aimed to contrast and to improve the information contained in the Archaeological Inventories about the closest area to “El Casetón de la Era II”, the first enclosure excavated in the North Meseta. The objective is to do the best with a future locational analysis that will bring new knowledge about a kind of sites that are changing many of the previous ideas about the Recent Prehistory in the middle Douro Valley.
Actas De Las Ii Jornadas De Jovenes En Investigacion Arqueologica Jia 09 Vol 2 2011 Isbn 978 84 7956 094 2 Pags 455 462, 2011
This paper summarizes the methodology applied to the study of the prehistoric occupation in the e... more This paper summarizes the methodology applied to the study of the prehistoric occupation in the environment close to the first enclosure excavated in the North Meseta: “El Casetón de la Era II”. The locational analysis was designed from some theoretic questions organized in 3 blocks: orography, visibility and accessibility. Using these questions as a guideline we established concepts as “orographic prominence” or “visual control” with a statistic parameter; besides, we chose evaluation criteria for the hypothesis, working guidelines and the most suitable software. The results stand out because of their analogical and objective nature in contrast of previous studies that express their conclusions in a digital and subjective way. To sum up, it’s a work model suitable for a fragmented archaeological record and for a plain landscape, which can, however, be useful to future researches in other contexts that search in the landscape the habitability decisions of the late societies.
Since 1975 the site of "Las Pozas" has named the Copper Age in ... more Since 1975 the site of "Las Pozas" has named the Copper Age in Spanish Northern Plateau. In the last decade several causewayed enclosures dated to this period have been discovered. This new situation has led us to revise the foundational site using remote sensing techniques. The infrared images have allowed us to distinguish two overlapping enclosures at "Las Pozas": a north one with three interrupted ditches and a southern group composed of two circles. This paper describes the characteristics of both enclosures using as well the information provided by 1979 and 1987 excavations. We believe this discovery certifies that causewayed enclosures were a common feature in the Douro Valley during the Copper Age.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2005
Sonnography and Tc-99m sestamibi scintigraphy are the most requested preoperative imaging tests n... more Sonnography and Tc-99m sestamibi scintigraphy are the most requested preoperative imaging tests nowdays in the surgery of hyperparathyroidism. The aim of our article is to know if Computerized Tomography (CT) and Magnetic Resonance Imaging (MRI) are useful as a location study and in which cases it would be more justified to ask these radiologic techniques. For that we report our results with 29 patients at all diagnosed as hyperparathyroidism (26 primary forms and 3 secondary ones) and operated by our E.N.T. Department later. On 20 of them a cervical CT was asked before the parathyroidectomy and on the rest 9, a MRI with sensitivities of 65% and 88.9% respectively. We think both complementary explorations must not be solicited by routine but they can represent a help in the cases in that sonnography and scintigraphy are not able to show the possible adenoma or hiperplasia, particularly in recurrent hyperparathyroidisms, reinterventions or suspect of parathyroid glands in an atypical location.
Sand flies are recognized as the major vector of canine visceral leishmaniasis. However, in some ... more Sand flies are recognized as the major vector of canine visceral leishmaniasis. However, in some areas of Brazil where sand flies do not occur, this disease is found in humans and dogs. There has been speculation that ticks might play a role in transmission of canine visceral leishmaniasis and the DNA of Leishmania spp. has been reported in whole ticks. We investigated the presence of Leishmania spp. promastigotes in the intestines, ovaries, and salivary glands of Rhipicephalus sanguineus ticks collected from tick-infested dogs in two cities of Brazil. We used 66 dogs that tested positive and 33 that tested negative for Leishmania spp. according to direct cytological examination assays. Ten ticks were collected from each dog and dissected to collect the intestines, ovaries, and salivary glands for immunohistochemistry (IHC) and diagnostic real-time polymerase chain reaction (RT-PCR). IHC results showed Leishmania spp. in 98, 14, and 8 % of the intestines, ovaries, and salivary gland...
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2005
Deep suprasternal infections secondary to cardiac surgery are uncommon but can compromise the lif... more Deep suprasternal infections secondary to cardiac surgery are uncommon but can compromise the life ofthe patient. After a sternotomy it is possible to find late cervico-thoracic abscesses specially in the presence of risk factors. We are reporting the case of a diabetic female of 67 years old with aortocoronary bypass who was diagnosed of suprasternal and neck base abscess in relation to her intervention 11 years later. It was necessary to practice drainage of the collection and wide spectrum antibioticotherapy with good evolution. 4 months after the surgery she was admitted again suffering a thoracic abscess that required treatment by Cardiac Surgery. The clinical follow-up was 3 years and no new recurrences have been detected.
Tick infestation may cause several problems including affecting domestic animal health and reduci... more Tick infestation may cause several problems including affecting domestic animal health and reducing the production of meat and milk, among others. Resistance to several classes of acaricides have been reported, forcing researchers to search for alternative measures, such as vaccines against ticks, to ensure tick control while having no or at least low negative impacts on the environment and public health. However, the current commercially available vaccines in different strains of Rhipicephalus microplus are reported to be of low efficacy. Fortunately, reverse vaccinology approaches have shown positive results in the new generation of vaccines. On this basis, a synthetic peptide from the ATAQ protein, which is present in the gut and Malpighi tubes of R. microplus, was synthesized. The ATAQ proteins were isolated, characterized and sequenced from several species of the genus Rhipicephalus. The alignment showed 93.3% identity among DNA sequences of ATAQs from these species. Because of this, immunization trials with this peptide were conducted on mice, rabbits and cattle to evaluate the humoral immune response and the efficacy against Rhipicephalus sanguineus in addition to R. microplus. Based on recent results, we conclude that reverse vaccinology is a promising approach because it is more accurate and faster than conventional methods in the detection of potential antigens to use in anti-tick vaccines. It is not only applicable against R. microplus but also against tick species that play important roles in spreading other diseases. ATAQ proteins should be considered as the antigen in new trials to develop a multi-antigenic vaccine. Although these peptides behave as hapten and are not able to be recognized by the immune system on its own, using carriers and adjuvants helps its presentation and induces strong immune responses. Furthermore, an efficiency of 35% reduction in overall life cycle parameters was reported for R. microplus (98% for ELISA responder animals) and 47% for R. sanguineus. Although not yet enough to prevent the environment to infestation of ticks, this still constitutes a promising strategy that could be applied to integrated measures on tick control and in new research that develops anti-tick vaccines.
Anales Otorrinolaringologicos Ibero Americanos, Feb 1, 2005
We report the clinical case of a 41 years old male with nasal obstruction of 1 year, epistaxis an... more We report the clinical case of a 41 years old male with nasal obstruction of 1 year, epistaxis and epiphora. The ENT exam showed a bleeding red mass in left nasal fossa and CT joint to IRM revealed a tumoral process on that level and informed about its extension to adyacents structures (cavum, ethmoides, sphenoids and maxillary sinus). The biopsy was positive for cystic adenoid carcinoma. Our patient was operated by paralateronasal rhinotomy with removal of the tumor. One year later we found recurrence on the left orbital floor and maxilar sinus. The Oncology Department informed that it was not possible a treatment with radiotherapy or chemotherapy because the low sensitivity of that lesion those treatment.
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Papers by Marcos Garcia