Zeitschrift Fur Psychologie-journal of Psychology, 2011
Traumatic stressors such as water boarding, electric shock, or false execution all activate simil... more Traumatic stressors such as water boarding, electric shock, or false execution all activate similar bodily, affective, and cognitive responses even when they are quite different from one another. As a result, the memory traces merge into a “trauma network” that includes sensory memories but becomes detached from the particular episodic memory; that is, the trauma network has no time or place. As, with increasing traumatic experiences, more and more cues become integrated in the network, the threshold for excitation is continually lowered and the individual is likely to show frequent alarm and other defense responses to reminders of the trauma. Neuroplastic mechanisms determine subsequent reorganization of brain circuitry in order to adapt to a presumed permanent need for defense. We hypothesized that aversive pictorial material is differentially processed in visual as well as frontal and limbic areas of the traumatized brain. We used Rapid Serial Visual Presentation (three pictures per second) to present aversive, neutral, and appetitive pictorial stimuli. Event-related magnetic fields were recorded in 41 survivors of torture and organized violence who suffered from posttraumatic stress disorder (PTSD) as well as 43 controls with a comparable ethnic background. Traumatized individuals showed an early shift in the processing of aversive pictures from sensory visual areas to fronto-temporal areas and the amygdala compared to controls without trauma-related symptoms. For survivors, as opposed to controls, these stimuli automatically activate aspects of the defense cascade and thus lead to an excitation of action-related neural activity. We conclude that an enlarged fear network in survivors of organized violence has a low excitation threshold, thus leading to prominent PTSD symptoms. A disintegration of the fear network by reconnecting its elements to the respective episodic memory or by some form of inhibition of the network may bring relief.
Depression has been characterized by lowered mood and unfavorable changes in neural emotional rea... more Depression has been characterized by lowered mood and unfavorable changes in neural emotional reactivity (altered brain responses to emotional stimuli). Physical exercise is a well‐established strategy to improve the mood of healthy and depressed individuals. Increasing evidence suggests that exercise might also improve emotional reactivity in healthy adults by increasing or decreasing brain responses to positive or negative stimuli, respectively. It is unknown, however, if exercise could also benefit emotional reactivity in depressed individuals. We investigated the effects of a single aerobic exercise session on mood and emotional reactivity in 24 depressed and 24 matched healthy young adults. Self‐reported mood and neural reactivity to emotional pictures (indexed by the EEG late positive potential, LPP) were assessed before and after two experimental protocols: exercise (36 min of moderate‐intensity exercise at 75% of maximal heart rate) and seated rest condition (36 min). In the healthy control group, exercise improved self‐reported mood and neural emotional reactivity (increasing LPP to positive pictures). In the depressed group, exercise improved self‐reported mood; however, it did not affect neural emotional reactivity. Additional analyses performed on both groups revealed that exercise‐induced changes in emotional reactivity are associated with the severity of depressive symptoms: the effectiveness of exercise in improving emotional reactivity decreases with the severity of depressive symptoms. Overall, the study further strengthens the claim of a beneficial role of exercise on mood and emotional reactivity. It also suggests that a single aerobic exercise session might have a limited influence on neural emotional reactivity in depressed individuals.
The visual processing of emotional faces is influenced by individual's le... more The visual processing of emotional faces is influenced by individual's level of stress and anxiety. Valence unspecific affective processing is expected to be influenced by predictability of threat. Using a design of phasic fear (predictable threat), sustained anxiety (unpredictable threat) and safety (no threat), we investigated the magnetoencephalographic correlates and temporal dynamics of emotional face processing in a sample of phobic patients. Compared to non-anxious controls, phobic individuals revealed decreased parietal emotional attention processes during affective processing at mid-latency and late processing stages. While control subjects showed increasing parietal processing of the facial stimuli in line with decreasing threat predictability, phobic subjects revealed the opposite pattern. Decreasing threat predictability also led to increasing neural activity in the orbitofrontal and dorsolateral prefrontal cortex at mid-latency stages. Additionally, unpredictability of threat lead to higher subjective discomfort compared to predictability of threat and no threat safety condition. Our findings indicate that visual processing of emotional information is influenced by both stress induction and pathologic anxiety.
Background Botulinum toxin A (BTX), a neurotoxin widely used for facial aesthetics, causes dose-d... more Background Botulinum toxin A (BTX), a neurotoxin widely used for facial aesthetics, causes dose-dependent muscle paralysis. It was hypothesized that treatment of mimic muscles with BTX might have a positive impact on emotional expression in static images (photographs), but a negative impact in dynamic recordings (videos). Objectives The aim of this study was to compare of emotional expression recorded in photographs and videos before and after treatment with BTX. Methods Twenty healthy women (mean age, 45 years) received a dose of 19 mouse units of XEOMIN (Merz, Frankfurt am Main, Germany) into the procerus, occipitofrontalis, and orbicularis oculi muscles. Photographs and videos of the participants’ faces with neutral and happy expressions were recorded before treatment and 2 weeks later. Recordings were rated by naive raters blind to the conditions and in balanced order. Results Videos were generally rated as more pleasant, arousing, attractive, and genuine than photographs (all Ps > 0.001). This was especially the case for videos with neutral expression (P = 0.003). Independent of presentation mode and facial expression, women were rated as more attractive after BTX treatment (P = 0.03). Conclusions In contrast to the hypothesis, the reduced mobility had no detectable negative impact on dynamic emotional expression, but videos received more positive ratings, particularly for neutral expressions. It is thus recommended to assess emotional expression with dynamic recordings to evaluate the effects of treatment with BTX. BTX seems to improve perceived attractiveness, although the cause of this effect remains unclear.
Zeitschrift Fur Psychologie-journal of Psychology, 2011
Traumatic stressors such as water boarding, electric shock, or false execution all activate simil... more Traumatic stressors such as water boarding, electric shock, or false execution all activate similar bodily, affective, and cognitive responses even when they are quite different from one another. As a result, the memory traces merge into a “trauma network” that includes sensory memories but becomes detached from the particular episodic memory; that is, the trauma network has no time or place. As, with increasing traumatic experiences, more and more cues become integrated in the network, the threshold for excitation is continually lowered and the individual is likely to show frequent alarm and other defense responses to reminders of the trauma. Neuroplastic mechanisms determine subsequent reorganization of brain circuitry in order to adapt to a presumed permanent need for defense. We hypothesized that aversive pictorial material is differentially processed in visual as well as frontal and limbic areas of the traumatized brain. We used Rapid Serial Visual Presentation (three pictures per second) to present aversive, neutral, and appetitive pictorial stimuli. Event-related magnetic fields were recorded in 41 survivors of torture and organized violence who suffered from posttraumatic stress disorder (PTSD) as well as 43 controls with a comparable ethnic background. Traumatized individuals showed an early shift in the processing of aversive pictures from sensory visual areas to fronto-temporal areas and the amygdala compared to controls without trauma-related symptoms. For survivors, as opposed to controls, these stimuli automatically activate aspects of the defense cascade and thus lead to an excitation of action-related neural activity. We conclude that an enlarged fear network in survivors of organized violence has a low excitation threshold, thus leading to prominent PTSD symptoms. A disintegration of the fear network by reconnecting its elements to the respective episodic memory or by some form of inhibition of the network may bring relief.
Depression has been characterized by lowered mood and unfavorable changes in neural emotional rea... more Depression has been characterized by lowered mood and unfavorable changes in neural emotional reactivity (altered brain responses to emotional stimuli). Physical exercise is a well‐established strategy to improve the mood of healthy and depressed individuals. Increasing evidence suggests that exercise might also improve emotional reactivity in healthy adults by increasing or decreasing brain responses to positive or negative stimuli, respectively. It is unknown, however, if exercise could also benefit emotional reactivity in depressed individuals. We investigated the effects of a single aerobic exercise session on mood and emotional reactivity in 24 depressed and 24 matched healthy young adults. Self‐reported mood and neural reactivity to emotional pictures (indexed by the EEG late positive potential, LPP) were assessed before and after two experimental protocols: exercise (36 min of moderate‐intensity exercise at 75% of maximal heart rate) and seated rest condition (36 min). In the healthy control group, exercise improved self‐reported mood and neural emotional reactivity (increasing LPP to positive pictures). In the depressed group, exercise improved self‐reported mood; however, it did not affect neural emotional reactivity. Additional analyses performed on both groups revealed that exercise‐induced changes in emotional reactivity are associated with the severity of depressive symptoms: the effectiveness of exercise in improving emotional reactivity decreases with the severity of depressive symptoms. Overall, the study further strengthens the claim of a beneficial role of exercise on mood and emotional reactivity. It also suggests that a single aerobic exercise session might have a limited influence on neural emotional reactivity in depressed individuals.
The visual processing of emotional faces is influenced by individual's le... more The visual processing of emotional faces is influenced by individual's level of stress and anxiety. Valence unspecific affective processing is expected to be influenced by predictability of threat. Using a design of phasic fear (predictable threat), sustained anxiety (unpredictable threat) and safety (no threat), we investigated the magnetoencephalographic correlates and temporal dynamics of emotional face processing in a sample of phobic patients. Compared to non-anxious controls, phobic individuals revealed decreased parietal emotional attention processes during affective processing at mid-latency and late processing stages. While control subjects showed increasing parietal processing of the facial stimuli in line with decreasing threat predictability, phobic subjects revealed the opposite pattern. Decreasing threat predictability also led to increasing neural activity in the orbitofrontal and dorsolateral prefrontal cortex at mid-latency stages. Additionally, unpredictability of threat lead to higher subjective discomfort compared to predictability of threat and no threat safety condition. Our findings indicate that visual processing of emotional information is influenced by both stress induction and pathologic anxiety.
Background Botulinum toxin A (BTX), a neurotoxin widely used for facial aesthetics, causes dose-d... more Background Botulinum toxin A (BTX), a neurotoxin widely used for facial aesthetics, causes dose-dependent muscle paralysis. It was hypothesized that treatment of mimic muscles with BTX might have a positive impact on emotional expression in static images (photographs), but a negative impact in dynamic recordings (videos). Objectives The aim of this study was to compare of emotional expression recorded in photographs and videos before and after treatment with BTX. Methods Twenty healthy women (mean age, 45 years) received a dose of 19 mouse units of XEOMIN (Merz, Frankfurt am Main, Germany) into the procerus, occipitofrontalis, and orbicularis oculi muscles. Photographs and videos of the participants’ faces with neutral and happy expressions were recorded before treatment and 2 weeks later. Recordings were rated by naive raters blind to the conditions and in balanced order. Results Videos were generally rated as more pleasant, arousing, attractive, and genuine than photographs (all Ps > 0.001). This was especially the case for videos with neutral expression (P = 0.003). Independent of presentation mode and facial expression, women were rated as more attractive after BTX treatment (P = 0.03). Conclusions In contrast to the hypothesis, the reduced mobility had no detectable negative impact on dynamic emotional expression, but videos received more positive ratings, particularly for neutral expressions. It is thus recommended to assess emotional expression with dynamic recordings to evaluate the effects of treatment with BTX. BTX seems to improve perceived attractiveness, although the cause of this effect remains unclear.
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