Gastric rupture is extremely rare in childhood beyond the neonatal period and the etiology of thi... more Gastric rupture is extremely rare in childhood beyond the neonatal period and the etiology of this condition in preschool children remains obscure. We report a case of 6 year old girl who sustained sudden and lethal gastric rupture. The young patient was affected by Incontinentia Pigmenti (IP), a genetic disease; she had an episode of nausea and vomiting the day before admission to the emergency ward. Abdominal X-ray showed free air in the abdominal cavity, an emergency laparotomy detected a wide perforation of posterior gastric wall. The post-operative course was complicated by a cardiac arrest and an autopsy was performed. Histological examination showed ulcerations and erosions in gastric mucosa with thrombosis in the blood vessel in the submucosa and it suggested Intestinal Neuronal Dysplasia (IND) type B. An eventual correlation between the three diseases that affected our patient was investigated. After a review of literature we have found that the presence of IP not appears t...
Maternal mortality and morbidity are the leading causes of death and illness, respectively, among... more Maternal mortality and morbidity are the leading causes of death and illness, respectively, among women of reproductive age in many countries throughout the world. Of all maternal deaths, those related to unsafe abortions are the most widely underestimated, but they are also the most largely preventable. Medical abortion is a safe and reliable method for termination of a pregnancy in early gestation, although it is important to be aware of signs and symptoms of severe infection and toxic shock syndrome after the medical termination of pregnancy; case studies in literature are rarely fatal events. We report the first case of septic shock syndrome following a clandestine pregnancy termination with a misoprostol-only regimen (12 tablets 200 μg each). Autopsy findings and histopathological examination proved that the woman died from septic shock. This case suggests to improve the forensic investigations in case of unsafe, often clandestine, abortion is suspected.
Gastric rupture is extremely rare in childhood beyond the neonatal period and the etiology of thi... more Gastric rupture is extremely rare in childhood beyond the neonatal period and the etiology of this condition in preschool children remains obscure. We report a case of 6 year old girl who sustained sudden and lethal gastric rupture. The young patient was affected by Incontinentia Pigmenti (IP), a genetic disease; she had an episode of nausea and vomiting the day before admission to the emergency ward. Abdominal X-ray showed free air in the abdominal cavity, an emergency laparotomy detected a wide perforation of posterior gastric wall. The post-operative course was complicated by a cardiac arrest and an autopsy was performed. Histological examination showed ulcerations and erosions in gastric mucosa with thrombosis in the blood vessel in the submucosa and it suggested Intestinal Neuronal Dysplasia (IND) type B. An eventual correlation between the three diseases that affected our patient was investigated. After a review of literature we have found that the presence of IP not appears t...
Maternal mortality and morbidity are the leading causes of death and illness, respectively, among... more Maternal mortality and morbidity are the leading causes of death and illness, respectively, among women of reproductive age in many countries throughout the world. Of all maternal deaths, those related to unsafe abortions are the most widely underestimated, but they are also the most largely preventable. Medical abortion is a safe and reliable method for termination of a pregnancy in early gestation, although it is important to be aware of signs and symptoms of severe infection and toxic shock syndrome after the medical termination of pregnancy; case studies in literature are rarely fatal events. We report the first case of septic shock syndrome following a clandestine pregnancy termination with a misoprostol-only regimen (12 tablets 200 μg each). Autopsy findings and histopathological examination proved that the woman died from septic shock. This case suggests to improve the forensic investigations in case of unsafe, often clandestine, abortion is suspected.
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