Background: Regarding the preventive approaches of traditional Persian medicine (TPM) in the mana... more Background: Regarding the preventive approaches of traditional Persian medicine (TPM) in the management of chronic diseases such as fatty liver, we evaluated the effect of a TPM-based nutritional style on liver enzymes levels and fatty liver grade in patients with non-alcoholic fatty liver.Materials and Methods: Patients were randomly assigned to receive either a three-month TPM-based diet as the intervention group or received the low-fat, low-calorie diet as the control group. The primary outcome measure was changes in serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Secondary outcome measures were changes in fatty liver grade (fatty tissue infiltration in liver by using ultrasound imaging) and changes in patients' body mass index (BMI). All outcome measures were evaluated at the baseline, at six weeks, and at three months after intervention.Results: Regarding within-group changes in outcome measures' mean values, there was a significant red...
A kind of growth hormone secretagogue (GHS), ghrelin, was first isolated from the rat stomach and... more A kind of growth hormone secretagogue (GHS), ghrelin, was first isolated from the rat stomach and plays a major role in the activation of the growth hormone secretagogue receptor 1a (GHS-R1a) resulting the release of growth hormone (GH). The preproghrelin gene is placed on chromosome 3, at locus 3p25 –2 in humans and constitutes five exons and three introns. Ghrelin is most plentifully expressed in particular cells in the oxyntic glands of the gastric epithelium, initially named X/A-like cells. Almost 60-70 % of circulating ghrelin is secreted by the stomach. Plasma ghrelin concentration alters throughout the day. Ghrelin has been suggested to act as a meal initiator because of its appetite-stimulating influences in free feeding rats in short period. In addition to ghrelin’s function as a meal motivator, it seems to contribute in long-term energy balance and nutritional status. In addition, many studies have been carried out in order to investigate the effects of natural and medicin...
Introduction: The present study aimed to evaluate the effects of hospitalization on the nutrition... more Introduction: The present study aimed to evaluate the effects of hospitalization on the nutritional status and prooxidant-antioxidant balance (PAB) of the patients with myocardial infarction (MI).Methods: This study was conducted on 57 patients diagnosed with MI with the mean age of 58.44±12.80 years. The patients were admitted to the cardiac care unit (CCU) of Ghaem Hospital in Mashhad, Iran. Nutritional status of the patients was assessed using the nutritional risk screening (NRS-2002) questionnaire. In addition, anthropometric and biochemical parameters and their changes were evaluated. PAB was also assessed as an oxidative stress marker. In total, 15 patients stayed in the hospital for more than one week. The measurements were performed upon admission and discharge.Results: Upon admission, 49.1% of the patients were well-nourished, and 50.9% were at nutritional risk. As expected, the patients were overweight (36.8%) or obese (19.2%), and all the measures of adiposity were high. ...
Introduction: The present study aimed to assess the effects of Ramadan fasting on micronutrients ... more Introduction: The present study aimed to assess the effects of Ramadan fasting on micronutrients and their correlations with ocular biometry. Methods: This prospective study was conducted on 89 healthy volunteers (51 males and 38 females) with the mean of 34.98±9.10 years in Mashhad, Iran. Participants received complete ophthalmic and systemic examinations one week before and one week after the holy month of Ramadan in 2015. Subjects with no history of systemic and ophthalmic diseases were enrolled in the study. Blood samples were obtained from all the participants in the morning in both phases of the study. Levels of micronutrients were measured in the blood samples using the Hitachi 717 analyzer (Hitachi, Japan). In addition, IOLMaster (Carl Zeiss Meditec AG, Germany) was applied to determine the ocular axial length (AL) and anterior chamber depth (ACD). Results: No significant differences were observed in the AL and ACD of the subjects before and after Ramadan fasting (P>0.05)...
Introduction: Bread is the staple food of most Muslims and can be considered to be a component wi... more Introduction: Bread is the staple food of most Muslims and can be considered to be a component with a remarkable effect on satiety and appetite during Ramadan fasting. This study aimed to present the recent advances in investigating the effect of different types of bread and enrichments on satiety and appetite. Methods: In this paper, articles focusing on the effect of various bread types (including enriched bread) on satiety and appetite, particularly during fasting were reviewed. Articles were found in databases such as ISI, PubMed and Google Scholar. Results: Different bread types with lower glycemic index are recommended for Ramadan fasting, especially for the Sahur meal, due to better satiety and sglycemic control. In addition, fermentable dietary fibers, such as arabinoxylans, I²-glucan, fructans, and resistant starch, can influence appetite through fermentation in the colon by saccharolytic bacteria and gastrointestinal tract releasing hormones changes. Consumption of wholeme...
Introduction: One of the most important factors in maintaining and improving children's healt... more Introduction: One of the most important factors in maintaining and improving children's health is the quality of diet. Given the importance of this issue and that so far the quality of children's diets has not been studied in Mashhad, this study was conducted to assess the quality of children's diets in Mashhad using the Healthy Eating Index (HEI). Methods: The diet of 723 children of 3 to 6 years old was collected by food frequency questionnaire (FFQ). FFQ information was evaluated with Nutritionist 4 software and the quality of children's diets was analyzed by HEI. SPSS software was used for statistical analysis, to examine the normality of data, and for comparison between parts of HEI on three levels, respectively, Kolmogorov-Smirnov and Chi-square test were used. Results: Overall90.6 of children did not have good quality of diet. However, 75.5 percent of children were receiving recommended amounts of bread and cereals. This diat for food groups of dairy, vegetabl...
Introduction: One of the obstetric problems and the most common causes of induction of labor is p... more Introduction: One of the obstetric problems and the most common causes of induction of labor is prolonged pregnancy which increases cesarean rate in addition to maternal and fetal complications. According to studies, date consumption has a role in the onset and progression of labor. This study was done to determine the effect of date consumption in late pregnancy on the onset of labor in nulliparous women. Methods: This clinical trial was conducted on 210 nulliparous women age 18-35 who referred to Omolbanin hospital of Mashhad, Iran in 2013. The women were divided randomly into two groups of 105 patients, experimental and control groups. The experimental group consumed dates, 70 to 75 grams daily from the week 37 of pregnancy until labor pain and in control group, usual care was performed without dates consumption. Data were gathered by a questionnaire form, physical examination, observing and counting fetal movement and check list of date consumption. Data were analyzed using SPSS software (version14), chi-square test and t-test. P value less than 0.05 was considered significant. Results: The onset of labor and showed a significant difference in two groups and labor induction was significantly higher in control group than experimental group (p<0.001). Mean of cervical dilatation on admission was significantly higher in experimental group than control group (p<0.001). But the type of delivery was not significantly different between two groups (p<0.2). Conclusion: The consumption of dates in late pregnancy increases spontaneous labor and as date is not contraindicated in pregnancy, it is recommended to consume in pregnant women in late pregnancy.
Introduction: During Ramadan, adult Muslims abstain from drinking and eating from sunrise to suns... more Introduction: During Ramadan, adult Muslims abstain from drinking and eating from sunrise to sunset. This religious practice influences individuals’ lifestyle factors such as eating behavior, meal schedule, and sleep pattern. These changes may affect endocrine and neuroendocrine circadian patterns, and consequently, cardiovascular indices. This study was performed to investigate the effects of Ramadan fasting on serum high-sensitivity C-reactive protein (Hs-CRP) and homocysteine as the risk factors for cardiovascular disease and body composition in the Iranian population. Methods: Healthy volunteers who fasted at least during 20 days of Ramadan were included in the study. Body composition and biochemical markers were measured pre- and post-Ramadan fasting. For normally distributed parameters, paired samples t-test was performed for analyzing the differences between the results, and Wilcoxon Signed Ranks test was run for non-normally distributed parameters. All the data was analyzed ...
Background: Regarding the preventive approaches of traditional Persian medicine (TPM) in the mana... more Background: Regarding the preventive approaches of traditional Persian medicine (TPM) in the management of chronic diseases such as fatty liver, we evaluated the effect of a TPM-based nutritional style on liver enzymes levels and fatty liver grade in patients with non-alcoholic fatty liver.Materials and Methods: Patients were randomly assigned to receive either a three-month TPM-based diet as the intervention group or received the low-fat, low-calorie diet as the control group. The primary outcome measure was changes in serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Secondary outcome measures were changes in fatty liver grade (fatty tissue infiltration in liver by using ultrasound imaging) and changes in patients' body mass index (BMI). All outcome measures were evaluated at the baseline, at six weeks, and at three months after intervention.Results: Regarding within-group changes in outcome measures' mean values, there was a significant red...
A kind of growth hormone secretagogue (GHS), ghrelin, was first isolated from the rat stomach and... more A kind of growth hormone secretagogue (GHS), ghrelin, was first isolated from the rat stomach and plays a major role in the activation of the growth hormone secretagogue receptor 1a (GHS-R1a) resulting the release of growth hormone (GH). The preproghrelin gene is placed on chromosome 3, at locus 3p25 –2 in humans and constitutes five exons and three introns. Ghrelin is most plentifully expressed in particular cells in the oxyntic glands of the gastric epithelium, initially named X/A-like cells. Almost 60-70 % of circulating ghrelin is secreted by the stomach. Plasma ghrelin concentration alters throughout the day. Ghrelin has been suggested to act as a meal initiator because of its appetite-stimulating influences in free feeding rats in short period. In addition to ghrelin’s function as a meal motivator, it seems to contribute in long-term energy balance and nutritional status. In addition, many studies have been carried out in order to investigate the effects of natural and medicin...
Introduction: The present study aimed to evaluate the effects of hospitalization on the nutrition... more Introduction: The present study aimed to evaluate the effects of hospitalization on the nutritional status and prooxidant-antioxidant balance (PAB) of the patients with myocardial infarction (MI).Methods: This study was conducted on 57 patients diagnosed with MI with the mean age of 58.44±12.80 years. The patients were admitted to the cardiac care unit (CCU) of Ghaem Hospital in Mashhad, Iran. Nutritional status of the patients was assessed using the nutritional risk screening (NRS-2002) questionnaire. In addition, anthropometric and biochemical parameters and their changes were evaluated. PAB was also assessed as an oxidative stress marker. In total, 15 patients stayed in the hospital for more than one week. The measurements were performed upon admission and discharge.Results: Upon admission, 49.1% of the patients were well-nourished, and 50.9% were at nutritional risk. As expected, the patients were overweight (36.8%) or obese (19.2%), and all the measures of adiposity were high. ...
Introduction: The present study aimed to assess the effects of Ramadan fasting on micronutrients ... more Introduction: The present study aimed to assess the effects of Ramadan fasting on micronutrients and their correlations with ocular biometry. Methods: This prospective study was conducted on 89 healthy volunteers (51 males and 38 females) with the mean of 34.98±9.10 years in Mashhad, Iran. Participants received complete ophthalmic and systemic examinations one week before and one week after the holy month of Ramadan in 2015. Subjects with no history of systemic and ophthalmic diseases were enrolled in the study. Blood samples were obtained from all the participants in the morning in both phases of the study. Levels of micronutrients were measured in the blood samples using the Hitachi 717 analyzer (Hitachi, Japan). In addition, IOLMaster (Carl Zeiss Meditec AG, Germany) was applied to determine the ocular axial length (AL) and anterior chamber depth (ACD). Results: No significant differences were observed in the AL and ACD of the subjects before and after Ramadan fasting (P>0.05)...
Introduction: Bread is the staple food of most Muslims and can be considered to be a component wi... more Introduction: Bread is the staple food of most Muslims and can be considered to be a component with a remarkable effect on satiety and appetite during Ramadan fasting. This study aimed to present the recent advances in investigating the effect of different types of bread and enrichments on satiety and appetite. Methods: In this paper, articles focusing on the effect of various bread types (including enriched bread) on satiety and appetite, particularly during fasting were reviewed. Articles were found in databases such as ISI, PubMed and Google Scholar. Results: Different bread types with lower glycemic index are recommended for Ramadan fasting, especially for the Sahur meal, due to better satiety and sglycemic control. In addition, fermentable dietary fibers, such as arabinoxylans, I²-glucan, fructans, and resistant starch, can influence appetite through fermentation in the colon by saccharolytic bacteria and gastrointestinal tract releasing hormones changes. Consumption of wholeme...
Introduction: One of the most important factors in maintaining and improving children's healt... more Introduction: One of the most important factors in maintaining and improving children's health is the quality of diet. Given the importance of this issue and that so far the quality of children's diets has not been studied in Mashhad, this study was conducted to assess the quality of children's diets in Mashhad using the Healthy Eating Index (HEI). Methods: The diet of 723 children of 3 to 6 years old was collected by food frequency questionnaire (FFQ). FFQ information was evaluated with Nutritionist 4 software and the quality of children's diets was analyzed by HEI. SPSS software was used for statistical analysis, to examine the normality of data, and for comparison between parts of HEI on three levels, respectively, Kolmogorov-Smirnov and Chi-square test were used. Results: Overall90.6 of children did not have good quality of diet. However, 75.5 percent of children were receiving recommended amounts of bread and cereals. This diat for food groups of dairy, vegetabl...
Introduction: One of the obstetric problems and the most common causes of induction of labor is p... more Introduction: One of the obstetric problems and the most common causes of induction of labor is prolonged pregnancy which increases cesarean rate in addition to maternal and fetal complications. According to studies, date consumption has a role in the onset and progression of labor. This study was done to determine the effect of date consumption in late pregnancy on the onset of labor in nulliparous women. Methods: This clinical trial was conducted on 210 nulliparous women age 18-35 who referred to Omolbanin hospital of Mashhad, Iran in 2013. The women were divided randomly into two groups of 105 patients, experimental and control groups. The experimental group consumed dates, 70 to 75 grams daily from the week 37 of pregnancy until labor pain and in control group, usual care was performed without dates consumption. Data were gathered by a questionnaire form, physical examination, observing and counting fetal movement and check list of date consumption. Data were analyzed using SPSS software (version14), chi-square test and t-test. P value less than 0.05 was considered significant. Results: The onset of labor and showed a significant difference in two groups and labor induction was significantly higher in control group than experimental group (p<0.001). Mean of cervical dilatation on admission was significantly higher in experimental group than control group (p<0.001). But the type of delivery was not significantly different between two groups (p<0.2). Conclusion: The consumption of dates in late pregnancy increases spontaneous labor and as date is not contraindicated in pregnancy, it is recommended to consume in pregnant women in late pregnancy.
Introduction: During Ramadan, adult Muslims abstain from drinking and eating from sunrise to suns... more Introduction: During Ramadan, adult Muslims abstain from drinking and eating from sunrise to sunset. This religious practice influences individuals’ lifestyle factors such as eating behavior, meal schedule, and sleep pattern. These changes may affect endocrine and neuroendocrine circadian patterns, and consequently, cardiovascular indices. This study was performed to investigate the effects of Ramadan fasting on serum high-sensitivity C-reactive protein (Hs-CRP) and homocysteine as the risk factors for cardiovascular disease and body composition in the Iranian population. Methods: Healthy volunteers who fasted at least during 20 days of Ramadan were included in the study. Body composition and biochemical markers were measured pre- and post-Ramadan fasting. For normally distributed parameters, paired samples t-test was performed for analyzing the differences between the results, and Wilcoxon Signed Ranks test was run for non-normally distributed parameters. All the data was analyzed ...
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