This study was carried out to investigate diet selection and eating behaviour of lactating German... more This study was carried out to investigate diet selection and eating behaviour of lactating German Fawn × Hair Crossbred goats in different feeding methods and levels. Twenty German Fawn × Hair first backcross does (B 1 ) were allocated into 4 treatment groups (2 feeding ...
Hintergrund: Ankylosierende Spondylitis (AS) ist eine multisystemische Erkrankung, bei der die Lu... more Hintergrund: Ankylosierende Spondylitis (AS) ist eine multisystemische Erkrankung, bei der die Lungenfunktion hauptsächlich durch die Restriktion der Brustwandbeteiligung beeinträchtigt wird. Vielfach wurde über einen restriktiven ventilatorischen Defekt berichtet, der vermutlich die Folge einer reduzierten Beweglichkeit des Brustkorbs ist. Bei AS zeigt die Atemfunktion ein typisch restriktives Muster, wobei die Dehnbarkeit der Lunge, die Diffusionskapazität und die arteriellen Blutgase unauffällig sind. Ziel: Ziel der Studie war ein Vergleich der Lungenfunktionstests (PFT), Atemmuskelkraft (MIP, MEP) und Ausdauer (MVV) bei AS im Früh- und Spätstadium. Methode:n In die Studie wurden 35 Patienten aufgenommen (30 Männer, 5 Frauen). Alle Patienten erfüllten die New Yorker Kriterien für AS. Sie wurden je nach Dauer der Erkrankung (<10 Jahre: Frühstadium, 20 Patienten; >10 Jahre: Spätstadium, 15 Patienten) eingeteilt und dann hinsichtlich PFT, MIP, MEP und MVV, Atemnot-Score, Erweiterung des Brustumfangs und BASFI-Score verglichen. Zusätzlich wurden 21 gesunde Probanden mit den AS-Patienten verglichen. Bei allen wurde die Erweiterung des Brustkorbs gemessen. Die Lungenfunktion wurde durch Spirometrie untersucht. Die Messung der Atemmuskelkraft erfolgte durch ein Munddruckmessgerät (MPM). Bei allen AS-Patienten wurde der funktionale Status durch BASFI erhoben. Ergebnisse: Der Body Mass Index (BMI) unterschied sich bei allen Gruppen nicht signifikant. FVC und FEV1 waren bei AS im Spätstadium signifikant niedriger (p=0,003, p=0,03, restriktiver ventilatorischer Defekt). Die Erweiterung des Brustkorbs war bei AS im Spätstadium signifikant geringer (p<0,05). Kein statistisch signifikanter Unterschied bestand bei MIP- und MEP-Werten zwischen AS im Spätstadium, AS im Frühstadium und gesunden Probanden (p>0,05). Die MVV war bei langjährigen AS-Patienten (p=0,05) signifikant vermindert. Obwohl BASFI und Atemnotwerte bei AS-Patienten im Spätstadium erhöht waren, erreichten sie keine statistische Signifikanz. Das Alter korrelierte negativ mit MIP- und MEP-Werten bei Patienten im Spätstadium (r=−0,733; p=0,02, r=−0,667; p=0,05). Schlussfolgerung: Unsere Studie zeigt, dass FVC, FEV1 (als Kennzeichen eines restriktiven Musters), MVV und Erweiterung des Brustumfangs bei langjähriger AS besonderes beeinträchtigt sind. Daher sollte man besonders bei Patienten im Frühstadium vor allem bestrebt sein, den Status des Brustkorbs zu verbessern. Diese Patienten sollten zu regelmäßigen Atemübungen angeregt werden, um die Einschränkung der Brustkorberweiterung zu verhindern und die kardiorespiratorische Fitness und Atemausdauer zu verbessern. Background: Ankylosing spondylitis (AS) is a multisystemic disease in which pulmonary function is altered owing mainly to the restriction of chest wall involvement. A restrictive ventilatory defect has been extensively reported. This has been suggested to be a consequence of reduced mobility of the thoracic cage. Respiratory function in AS shows a typical restrictive pattern but pulmonary compliance, diffusion capacity, and arterial blood gases are normal. Objective: The objective of the present study was to compare pulmonary function tests (PFT), respiratory muscle strength (MIP, MEP) and endurance (MVV) in early and late AS. Methods: A total of 35 patients (30 males, 5 females) took part, all of whom met the New York criteria for AS. Patients were divided into two groups for the comparison of early (disease duration <10 years, 20 patients) and late (disease duration >10 years, 15 patients) manifestations in pulmonary function tests, respiratory muscle strength and endurance, dyspnea score, chest expansion, and BASFI score. In addition, 21 healthy controls were compared with the AS patients. Measurement of chest expansion was performed in all subjects. Pulmonary function tests were performed by spirometry. Respiratory muscle strength was evaluated by a mouth pressure meter (MPM). Functional status was assessed by BASFI in all AS patients. Results: There was no significant difference in body mass index between the groups. The FVC and FEV1 were significantly lower in late AS (p=0.003, p=0.03, restrictive ventilatory defect ). Chest expansion was significantly lower in late AS (p<0.05). There was no significant difference for MIP or MEP values between late AS, early AS and the controls (p>0.05). Endurance (MVV) was significantly lower in late AS patients (p=0.05). Although the BASFI and dyspnea scores were higher in late AS, they did not reach significant levels. In addition, age was negatively correlated with MIP and MEP in late AS (r=−0.733; p=0.02, r=−0.667; p=0.05). Conclusion: This study demonstrates that FVC and FEV1 (hallmarks of a restrictive pattern), MVV (endurance) and chest expansion are especially involved in long-standing AS. Therefore, improvement of the thoracic cage should be taken into consideration, especially in early AS. These patients should be encouraged to make regular respiratory exercises for preventing the limitation of chest expansion and also improving cardiopulmonary fitness and respiratory endurance.
... 1 Department of Physics, Art and Science Faculty, Süleyman Demirel University, Isparta, Turke... more ... 1 Department of Physics, Art and Science Faculty, Süleyman Demirel University, Isparta, Turkey 2 Department of Physics, Art and Science Faculty, Gaziosmanpasa University, Tokat, Turkey E-mail: sahin@fef.sdu.edu.tr and sduosman@gmail.com ...
P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this... more P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 ± 10 years) and 27 healthy controls (mean age 47 ± 8 years) were included in the study. We performed electrocardiography and Doppler echocardiography on patients and controls. Maximum and minimum P wave duration were obtained from electrocardiographic measurements. PWD defined as the difference between maximum and minimum P wave duration was also calculated. Maximum P wave duration and PWD was higher in RA patients than controls (P = 0.031 and P = 0.001, respectively). However, there was no significant difference in minimum P wave duration between the two groups (P = 0.152). There was significant correlation between PWD and disease duration (r = 0.375, P = 0.009) and isovolumetric relaxation time (r = 0.390, P = 0.006). P wave duration and PWD was found to be higher in RA patients than healthy control subjects. PWD is closely associated with disease duration and left ventricular (LV) diastolic dysfunction.
Pulmonary function is altered in ankylosing spondylitis (AS) owing mainly to the restriction of c... more Pulmonary function is altered in ankylosing spondylitis (AS) owing mainly to the restriction of chest wall involvement (limited chest expansion). The objective of this study was to investigate the relationship between chest expansion, respiratory muscle strength (MIP, MEP) maximum voluntary ventilation (MVV), and BASFI score in patients with AS. Twenty-three male patients with definite AS and 21 age-matched healthy male controls were recruited for the study. Patients with AS were assessed for functional status by BASFI. Measurement of chest expansion and lumbar spinal flexion (modified Schober) method was performed in all subjects. Pulmonary function tests were performed by spirometry. Respiratory muscle strength was evaluated by a mouth-pressure meter (MPM). Body mass index (kg/m2) was recorded in all individuals. Chest expansion and modified Schober measurement were significantly lower in AS patients (p<0.05). Pulmonary function tests revealed restrictive lung disease. The mean BASFI score suggested good functional capacity in the AS group. The respiratory muscle strength and MVV were also lower in AS (p<0.05). The chest expansion was correlated with MIP and MEP values (r=0.491; p=0.02, r=0.436; p=0.05). Chest expansion was also correlated negatively with disease duration (r=−0.502; p=0.03). In addition, there was no correlation between chest expansion and BASFI score (r=−0.076; p=0.773). This study demonstrates that functional status (BASFI) is not influenced by the limitation of chest wall movement. It may be as a result of the maintenance of moderate physical activity during active life in patients with AS.
This study was carried out to investigate diet selection and eating behaviour of lactating German... more This study was carried out to investigate diet selection and eating behaviour of lactating German Fawn × Hair Crossbred goats in different feeding methods and levels. Twenty German Fawn × Hair first backcross does (B 1 ) were allocated into 4 treatment groups (2 feeding ...
Hintergrund: Ankylosierende Spondylitis (AS) ist eine multisystemische Erkrankung, bei der die Lu... more Hintergrund: Ankylosierende Spondylitis (AS) ist eine multisystemische Erkrankung, bei der die Lungenfunktion hauptsächlich durch die Restriktion der Brustwandbeteiligung beeinträchtigt wird. Vielfach wurde über einen restriktiven ventilatorischen Defekt berichtet, der vermutlich die Folge einer reduzierten Beweglichkeit des Brustkorbs ist. Bei AS zeigt die Atemfunktion ein typisch restriktives Muster, wobei die Dehnbarkeit der Lunge, die Diffusionskapazität und die arteriellen Blutgase unauffällig sind. Ziel: Ziel der Studie war ein Vergleich der Lungenfunktionstests (PFT), Atemmuskelkraft (MIP, MEP) und Ausdauer (MVV) bei AS im Früh- und Spätstadium. Methode:n In die Studie wurden 35 Patienten aufgenommen (30 Männer, 5 Frauen). Alle Patienten erfüllten die New Yorker Kriterien für AS. Sie wurden je nach Dauer der Erkrankung (<10 Jahre: Frühstadium, 20 Patienten; >10 Jahre: Spätstadium, 15 Patienten) eingeteilt und dann hinsichtlich PFT, MIP, MEP und MVV, Atemnot-Score, Erweiterung des Brustumfangs und BASFI-Score verglichen. Zusätzlich wurden 21 gesunde Probanden mit den AS-Patienten verglichen. Bei allen wurde die Erweiterung des Brustkorbs gemessen. Die Lungenfunktion wurde durch Spirometrie untersucht. Die Messung der Atemmuskelkraft erfolgte durch ein Munddruckmessgerät (MPM). Bei allen AS-Patienten wurde der funktionale Status durch BASFI erhoben. Ergebnisse: Der Body Mass Index (BMI) unterschied sich bei allen Gruppen nicht signifikant. FVC und FEV1 waren bei AS im Spätstadium signifikant niedriger (p=0,003, p=0,03, restriktiver ventilatorischer Defekt). Die Erweiterung des Brustkorbs war bei AS im Spätstadium signifikant geringer (p<0,05). Kein statistisch signifikanter Unterschied bestand bei MIP- und MEP-Werten zwischen AS im Spätstadium, AS im Frühstadium und gesunden Probanden (p>0,05). Die MVV war bei langjährigen AS-Patienten (p=0,05) signifikant vermindert. Obwohl BASFI und Atemnotwerte bei AS-Patienten im Spätstadium erhöht waren, erreichten sie keine statistische Signifikanz. Das Alter korrelierte negativ mit MIP- und MEP-Werten bei Patienten im Spätstadium (r=−0,733; p=0,02, r=−0,667; p=0,05). Schlussfolgerung: Unsere Studie zeigt, dass FVC, FEV1 (als Kennzeichen eines restriktiven Musters), MVV und Erweiterung des Brustumfangs bei langjähriger AS besonderes beeinträchtigt sind. Daher sollte man besonders bei Patienten im Frühstadium vor allem bestrebt sein, den Status des Brustkorbs zu verbessern. Diese Patienten sollten zu regelmäßigen Atemübungen angeregt werden, um die Einschränkung der Brustkorberweiterung zu verhindern und die kardiorespiratorische Fitness und Atemausdauer zu verbessern. Background: Ankylosing spondylitis (AS) is a multisystemic disease in which pulmonary function is altered owing mainly to the restriction of chest wall involvement. A restrictive ventilatory defect has been extensively reported. This has been suggested to be a consequence of reduced mobility of the thoracic cage. Respiratory function in AS shows a typical restrictive pattern but pulmonary compliance, diffusion capacity, and arterial blood gases are normal. Objective: The objective of the present study was to compare pulmonary function tests (PFT), respiratory muscle strength (MIP, MEP) and endurance (MVV) in early and late AS. Methods: A total of 35 patients (30 males, 5 females) took part, all of whom met the New York criteria for AS. Patients were divided into two groups for the comparison of early (disease duration <10 years, 20 patients) and late (disease duration >10 years, 15 patients) manifestations in pulmonary function tests, respiratory muscle strength and endurance, dyspnea score, chest expansion, and BASFI score. In addition, 21 healthy controls were compared with the AS patients. Measurement of chest expansion was performed in all subjects. Pulmonary function tests were performed by spirometry. Respiratory muscle strength was evaluated by a mouth pressure meter (MPM). Functional status was assessed by BASFI in all AS patients. Results: There was no significant difference in body mass index between the groups. The FVC and FEV1 were significantly lower in late AS (p=0.003, p=0.03, restrictive ventilatory defect ). Chest expansion was significantly lower in late AS (p<0.05). There was no significant difference for MIP or MEP values between late AS, early AS and the controls (p>0.05). Endurance (MVV) was significantly lower in late AS patients (p=0.05). Although the BASFI and dyspnea scores were higher in late AS, they did not reach significant levels. In addition, age was negatively correlated with MIP and MEP in late AS (r=−0.733; p=0.02, r=−0.667; p=0.05). Conclusion: This study demonstrates that FVC and FEV1 (hallmarks of a restrictive pattern), MVV (endurance) and chest expansion are especially involved in long-standing AS. Therefore, improvement of the thoracic cage should be taken into consideration, especially in early AS. These patients should be encouraged to make regular respiratory exercises for preventing the limitation of chest expansion and also improving cardiopulmonary fitness and respiratory endurance.
... 1 Department of Physics, Art and Science Faculty, Süleyman Demirel University, Isparta, Turke... more ... 1 Department of Physics, Art and Science Faculty, Süleyman Demirel University, Isparta, Turkey 2 Department of Physics, Art and Science Faculty, Gaziosmanpasa University, Tokat, Turkey E-mail: sahin@fef.sdu.edu.tr and sduosman@gmail.com ...
P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this... more P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 ± 10 years) and 27 healthy controls (mean age 47 ± 8 years) were included in the study. We performed electrocardiography and Doppler echocardiography on patients and controls. Maximum and minimum P wave duration were obtained from electrocardiographic measurements. PWD defined as the difference between maximum and minimum P wave duration was also calculated. Maximum P wave duration and PWD was higher in RA patients than controls (P = 0.031 and P = 0.001, respectively). However, there was no significant difference in minimum P wave duration between the two groups (P = 0.152). There was significant correlation between PWD and disease duration (r = 0.375, P = 0.009) and isovolumetric relaxation time (r = 0.390, P = 0.006). P wave duration and PWD was found to be higher in RA patients than healthy control subjects. PWD is closely associated with disease duration and left ventricular (LV) diastolic dysfunction.
Pulmonary function is altered in ankylosing spondylitis (AS) owing mainly to the restriction of c... more Pulmonary function is altered in ankylosing spondylitis (AS) owing mainly to the restriction of chest wall involvement (limited chest expansion). The objective of this study was to investigate the relationship between chest expansion, respiratory muscle strength (MIP, MEP) maximum voluntary ventilation (MVV), and BASFI score in patients with AS. Twenty-three male patients with definite AS and 21 age-matched healthy male controls were recruited for the study. Patients with AS were assessed for functional status by BASFI. Measurement of chest expansion and lumbar spinal flexion (modified Schober) method was performed in all subjects. Pulmonary function tests were performed by spirometry. Respiratory muscle strength was evaluated by a mouth-pressure meter (MPM). Body mass index (kg/m2) was recorded in all individuals. Chest expansion and modified Schober measurement were significantly lower in AS patients (p<0.05). Pulmonary function tests revealed restrictive lung disease. The mean BASFI score suggested good functional capacity in the AS group. The respiratory muscle strength and MVV were also lower in AS (p<0.05). The chest expansion was correlated with MIP and MEP values (r=0.491; p=0.02, r=0.436; p=0.05). Chest expansion was also correlated negatively with disease duration (r=−0.502; p=0.03). In addition, there was no correlation between chest expansion and BASFI score (r=−0.076; p=0.773). This study demonstrates that functional status (BASFI) is not influenced by the limitation of chest wall movement. It may be as a result of the maintenance of moderate physical activity during active life in patients with AS.
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