Targeting properties of vertically transmitted viruses in early infancy is important to understan... more Targeting properties of vertically transmitted viruses in early infancy is important to understand disease progression. To investigate genotypic characteristics of transmitted viruses, blood samples were obtained from infants aged 6 weeks-18 months, categorized in two age groups, acute (≤6 months) and early (>6-18 months). Nef having an important role in pathogenesis was selected to explore the viral characteristics. A total of 57 PCR positive samples, amplified by nef gene were sequenced. Analysis showed that 50 sequences belonged to subtype C. In one sequence of acute age group, a long insertion of 10 residues (AAERMRRAEP) in variable region and a 13 residues deletion (ATNNADCAWLEAQ) around proteolytic cleavage region of gene in another sequence was observed. Insertions were also observed in sequences of early age group, however, they ranged from 2-8 residues only. In one sequence of early age group, 3/4 Arginines at positions 19,21,22 of Arginine cluster were mutated to Glutam...
Many emerging countries in recent decades have relied on a development strategy that focused prim... more Many emerging countries in recent decades have relied on a development strategy that focused primarily on promoting the manufacturing sector and the exports of manufactured goods. However, an acceleration of growth in manufacturing, and a concomitant increase in ...
Indian Journal of Chemistry Sect B Organic Chemistry Including Medical Chemistry, 2009
... Anand Sachar, Poonam Gupta, Shallu Gupta & RL Sharma* Department of Chemistry, Un... more ... Anand Sachar, Poonam Gupta, Shallu Gupta & RL Sharma* Department of Chemistry, University of Jammu, Jammu 180 006, India E-mail: rlsharma_hod ... The 1H and 13C NMR spectra were run on Varian Unity 500 MHz NMR spectrometer using TMS as an internal standard ...
Targeting properties of vertically transmitted viruses in early infancy is important to understan... more Targeting properties of vertically transmitted viruses in early infancy is important to understand disease progression. To investigate genotypic characteristics of transmitted viruses, blood samples were obtained from infants aged 6 weeks-18 months, categorized in two age groups, acute (≤6 months) and early (>6-18 months). Nef having an important role in pathogenesis was selected to explore the viral characteristics. A total of 57 PCR positive samples, amplified by nef gene were sequenced. Analysis showed that 50 sequences belonged to subtype C. In one sequence of acute age group, a long insertion of 10 residues (AAERMRRAEP) in variable region and a 13 residues deletion (ATNNADCAWLEAQ) around proteolytic cleavage region of gene in another sequence was observed. Insertions were also observed in sequences of early age group, however, they ranged from 2-8 residues only. In one sequence of early age group, 3/4 Arginines at positions 19,21,22 of Arginine cluster were mutated to Glutam...
Many emerging countries in recent decades have relied on a development strategy that focused prim... more Many emerging countries in recent decades have relied on a development strategy that focused primarily on promoting the manufacturing sector and the exports of manufactured goods. However, an acceleration of growth in manufacturing, and a concomitant increase in ...
Indian Journal of Chemistry Sect B Organic Chemistry Including Medical Chemistry, 2009
... Anand Sachar, Poonam Gupta, Shallu Gupta & RL Sharma* Department of Chemistry, Un... more ... Anand Sachar, Poonam Gupta, Shallu Gupta & RL Sharma* Department of Chemistry, University of Jammu, Jammu 180 006, India E-mail: rlsharma_hod ... The 1H and 13C NMR spectra were run on Varian Unity 500 MHz NMR spectrometer using TMS as an internal standard ...
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