Immunochemical techniques offer many advantages over chromatographic methods currently used for p... more Immunochemical techniques offer many advantages over chromatographic methods currently used for pesticide trace analysis of substrates such as soil, water, plants, urine, and blood. These advantages include speed of processing seunples, high specificity for detecting the pesticide of interest, reduced amount of preparation and cleanup of the sample prior to analysis, and a dramatic increase in the number of samples that can be analyzed. Immunoassays are based on the principle that antibodies to pesticides can be prepared, in animals, that can recognize and attach with equisite specificity to certain chemical configurations displayed on the surface of a molecule. Small molecules such as herbicides are not usually immunogenic but can be made so by chemically bonding them to a large immunogenic protein such as bovine serum albumin prior to injection into an animal. Development of herbicide specific antibodies and their use in direct and indirect enzyme linked immunosorbent assays (EIA ...
Immunochemical techniques offer many advantages over chromatographic methods currently used for p... more Immunochemical techniques offer many advantages over chromatographic methods currently used for pesticide trace analysis of substrates such as soil, water, plants, urine, and blood. These advantages include speed of processing seunples, high specificity for detecting the pesticide of interest, reduced amount of preparation and cleanup of the sample prior to analysis, and a dramatic increase in the number of samples that can be analyzed. Immunoassays are based on the principle that antibodies to pesticides can be prepared, in animals, that can recognize and attach with equisite specificity to certain chemical configurations displayed on the surface of a molecule. Small molecules such as herbicides are not usually immunogenic but can be made so by chemically bonding them to a large immunogenic protein such as bovine serum albumin prior to injection into an animal. Development of herbicide specific antibodies and their use in direct and indirect enzyme linked immunosorbent assays (EIA ...
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