Archives of Physical Medicine and Rehabilitation, Sep 1, 2022
OBJECTIVE Primary: 1) To evaluate the completeness of reporting of randomized controlled trials (... more OBJECTIVE Primary: 1) To evaluate the completeness of reporting of randomized controlled trials (RCTs) published in rehabilitation journals through the evaluation of the adherence to the CONSORT checklist, 2) to investigate the relationship between reporting and risk of bias (ROB). Secondary: to study the association between completeness of reporting and the characteristics of studies and journals. DATA SOURCES A random sample of 200 RCTs published between 2011 and 2020 in 68 rehabilitation journals indexed under the "rehabilitation" category in the InCites Journal Citation Report. STUDY SELECTION One reviewer evaluated the completeness of reporting operationalised as the adherence to the CONSORT checklist. Two independent reviewers evaluated the ROB using the Cochrane ROB 2.0 tool. DATA EXTRACTION Overall adherence and adherence to each CONSORT section were calculated. Regression analyses investigated the association between completeness of reporting, ROB and other characteristics (quartile range, publication modalities and study protocol registration). DATA SYNTHESIS The mean overall CONSORT adherence across studies was 65%. Studies with high ROB have less adherence than those with low ROB (-5.5%; CI -10.9; -0.0). There was a 10.2% (CI% 6.2; 14.3) increase in adherence if the RCT protocol was registered. Studies published in first quartile journals displayed an overall adherence of 11.7% (CI% 17.1; 6.4) higher than those published in the fourth quartile. CONCLUSION Reporting completeness is still suboptimal and it is associated with ROB, journal impact ranking and registration of the study protocol. Trial authors should improve adherence to the CONSORT guideline and journal editors should adopt new strategies to improve the reporting.
BackgroundExercise therapy is a common intervention recommended for chronic low back pain (cLBP).... more BackgroundExercise therapy is a common intervention recommended for chronic low back pain (cLBP). Although adequate reporting of intervention is crucial to understand and replicate exercise therapy, it does not help clinicians to determine the therapeutic quality. So The international Consensus on Therapeutic Exercise aNd Training (i-CONTENT) tool was developed to assess therapeutic quality of exercise. Therefore, we will assess the therapeutic quality of different exercise interventions by i-CONTENT tool in cLBP RCTs and its inter-rater reliability.MethodsWe will perform a meta-research study, starting from Cochrane review publication “Exercise therapy for chronic low back pain”. We will select a random sample of 100 arms with different type of exercises included (i.e. Core Strengthening, General Strengthening, Stretching, Aerobic exercises, Motor Control, Pilates, McKenzie, Qigong, Yoga, Tai Chi). For each included study’s arm, two pairs of independent reviewers will assess the th...
ABSTRACTBackgroundStudies that develop and/or validate a clinical (diagnostic or prognostic) pred... more ABSTRACTBackgroundStudies that develop and/or validate a clinical (diagnostic or prognostic) prediction model should be reported with sufficient details to enable the clinician to use the model in clinical practice. Also, an adequate reporting enables researchers to externally validate the model and assess its validity and reliability. To improve the reporting of multivariable prediction models, the TRIPOD checklist was released in 2015.ObjectiveEvaluate the quality of reporting of prediction model studies conducted in patients with back pain, neck pain or osteoarthritis.MethodsWe will perform a systematic review of the literature, searching MEDLINE (via Ovid), Embase, Web of Science, and CINHAL (via EBSCO) for studies that describe a model development, external validation, update, or a combination of these in patients with back pain, neck pain or osteoarthritis. The completeness of the reporting will be evaluated using a specific adherence assessment form of the TRIPOD. Two authors...
ABSTRACTBackground and ObjectivesRisk of bias is a critical issue to consider when appraising stu... more ABSTRACTBackground and ObjectivesRisk of bias is a critical issue to consider when appraising studies. Generally, the higher the risk of bias of a study, the less confidence there will be that the results are valid. Considering that low back pain is recognized to have an extremely high disease burden; exercise therapy is one of the most frequently prescribed interventions for chronic low back pain (CLBP) and that most low back pain trials have methodological limitations that could bias treatment effect estimates; the objective of this study is to explore causal pathways between the sources of risk of bias and estimates of the treatment effect of exercise therapy interventions in CLBP trials.MethodsThe 249 RCTs included in the 2021 Cochrane review publication “Exercise therapy for chronic low back pain” will be included. The risk of bias will be evaluated with the Cochrane Risk of Bias 2 tool (ROB 2). Causal pathways between the exposure (risk of bias domains) and our outcomes of int...
Archives of Physical Medicine and Rehabilitation, Sep 1, 2022
OBJECTIVE Primary: 1) To evaluate the completeness of reporting of randomized controlled trials (... more OBJECTIVE Primary: 1) To evaluate the completeness of reporting of randomized controlled trials (RCTs) published in rehabilitation journals through the evaluation of the adherence to the CONSORT checklist, 2) to investigate the relationship between reporting and risk of bias (ROB). Secondary: to study the association between completeness of reporting and the characteristics of studies and journals. DATA SOURCES A random sample of 200 RCTs published between 2011 and 2020 in 68 rehabilitation journals indexed under the "rehabilitation" category in the InCites Journal Citation Report. STUDY SELECTION One reviewer evaluated the completeness of reporting operationalised as the adherence to the CONSORT checklist. Two independent reviewers evaluated the ROB using the Cochrane ROB 2.0 tool. DATA EXTRACTION Overall adherence and adherence to each CONSORT section were calculated. Regression analyses investigated the association between completeness of reporting, ROB and other characteristics (quartile range, publication modalities and study protocol registration). DATA SYNTHESIS The mean overall CONSORT adherence across studies was 65%. Studies with high ROB have less adherence than those with low ROB (-5.5%; CI -10.9; -0.0). There was a 10.2% (CI% 6.2; 14.3) increase in adherence if the RCT protocol was registered. Studies published in first quartile journals displayed an overall adherence of 11.7% (CI% 17.1; 6.4) higher than those published in the fourth quartile. CONCLUSION Reporting completeness is still suboptimal and it is associated with ROB, journal impact ranking and registration of the study protocol. Trial authors should improve adherence to the CONSORT guideline and journal editors should adopt new strategies to improve the reporting.
BackgroundExercise therapy is a common intervention recommended for chronic low back pain (cLBP).... more BackgroundExercise therapy is a common intervention recommended for chronic low back pain (cLBP). Although adequate reporting of intervention is crucial to understand and replicate exercise therapy, it does not help clinicians to determine the therapeutic quality. So The international Consensus on Therapeutic Exercise aNd Training (i-CONTENT) tool was developed to assess therapeutic quality of exercise. Therefore, we will assess the therapeutic quality of different exercise interventions by i-CONTENT tool in cLBP RCTs and its inter-rater reliability.MethodsWe will perform a meta-research study, starting from Cochrane review publication “Exercise therapy for chronic low back pain”. We will select a random sample of 100 arms with different type of exercises included (i.e. Core Strengthening, General Strengthening, Stretching, Aerobic exercises, Motor Control, Pilates, McKenzie, Qigong, Yoga, Tai Chi). For each included study’s arm, two pairs of independent reviewers will assess the th...
ABSTRACTBackgroundStudies that develop and/or validate a clinical (diagnostic or prognostic) pred... more ABSTRACTBackgroundStudies that develop and/or validate a clinical (diagnostic or prognostic) prediction model should be reported with sufficient details to enable the clinician to use the model in clinical practice. Also, an adequate reporting enables researchers to externally validate the model and assess its validity and reliability. To improve the reporting of multivariable prediction models, the TRIPOD checklist was released in 2015.ObjectiveEvaluate the quality of reporting of prediction model studies conducted in patients with back pain, neck pain or osteoarthritis.MethodsWe will perform a systematic review of the literature, searching MEDLINE (via Ovid), Embase, Web of Science, and CINHAL (via EBSCO) for studies that describe a model development, external validation, update, or a combination of these in patients with back pain, neck pain or osteoarthritis. The completeness of the reporting will be evaluated using a specific adherence assessment form of the TRIPOD. Two authors...
ABSTRACTBackground and ObjectivesRisk of bias is a critical issue to consider when appraising stu... more ABSTRACTBackground and ObjectivesRisk of bias is a critical issue to consider when appraising studies. Generally, the higher the risk of bias of a study, the less confidence there will be that the results are valid. Considering that low back pain is recognized to have an extremely high disease burden; exercise therapy is one of the most frequently prescribed interventions for chronic low back pain (CLBP) and that most low back pain trials have methodological limitations that could bias treatment effect estimates; the objective of this study is to explore causal pathways between the sources of risk of bias and estimates of the treatment effect of exercise therapy interventions in CLBP trials.MethodsThe 249 RCTs included in the 2021 Cochrane review publication “Exercise therapy for chronic low back pain” will be included. The risk of bias will be evaluated with the Cochrane Risk of Bias 2 tool (ROB 2). Causal pathways between the exposure (risk of bias domains) and our outcomes of int...
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Papers by Raymond Ostelo