Tujuan penelitian ini adalah untuk mengetahui: (1) perbedaan pengaruh latihan beban menggunakan s... more Tujuan penelitian ini adalah untuk mengetahui: (1) perbedaan pengaruh latihan beban menggunakan sistem single set dan multiple sets terhadap peningkatan daya tahan anaerobik, (2) perbedaan antara pemain sepak bola yang memiliki daya tahan aerobik tinggi dan rendah terhadap peningkatan daya tahan anaerobik, dan (3) interaksi antara metode latihan beban dan daya tahan aerobik dalam meningkatkan daya tahan anaerobik. Penelitian ini menggunakan metode eksperimen dengan rancangan desain faktorial 2x2. Teknik analisis data menggunakan analisis varian (anava) pada taraf signifikansi (α) 0.05. Populasi dalam penelitian ini adalah pemain PS FKIP UNIB yang berjumlah 33 orang. Teknik pengambilan sampel menggunakan purposive sampling dengan jumlah sampel sebanyak 18 atlet. Instrumen dalam penelitian ini adalah tes daya tahan aerobik dengan cooper test dan daya tahan anaerobik dengan running-based anaerobic sprint test. Hasil penelitian menunjukkan: (1) terdapat pengaruh yang signifikan antara l...
The appearance of myofibroblasts is hallmark of fibrosis and tissue repair. Myofibroblasts are st... more The appearance of myofibroblasts is hallmark of fibrosis and tissue repair. Myofibroblasts are stromal cells that transition from fibroblastic progenitors by acquiring new contractile function. Platelet-derived growth factor (PDGF) promotes fibrosis and supports tissue repair, but the relationship between PDGF and the myofibroblast phenotype is unclear. Using mice with PDGF receptor α (PDGFRα) gene activation or deletion and mutation-linked lineage tracing, we examine fibroblastic progenitor cell fate during spontaneous fibrosis and wound-induced fibrosis. Unexpectedly, elevated PDGFRα signaling generates fibrosis while inhibiting myofibroblast formation. Non-canonical TGFβ-p38 signaling is blocked by PDGFRα activity, thereby inhibiting myofibroblasts. However, deletion of PDGFRα also inhibits myofibroblasts by reducing SRF activity, which leads to defective wound repair. Our findings suggest a scenario where PDGFRα initially expands the progenitor population for tissue repair and later suppression of PDGFRα in activated progenitors permits their transition to myofibroblast.
the aim of this research was to understand the effects of weight training method with the use of ... more the aim of this research was to understand the effects of weight training method with the use of single set and multiple sets system and aerobic endurance in improving anaerobic endurance. This research made use of experimental method of 2x2 factorial design. The population in this study were 33 football players of PS FKIP UNIB. Purposive sampling technique was employed in this study and 18 people participated. The instruments used in this study were aerobic endurance tests through the use of Cooper test as well as anaerobic endurance through the use of running-based anaerobic sprint test. The result revealed that weight training with multiple sets system was more significant in increasing anaerobic endurance rather than exercises with single set system. Keywords—weight training, single set, multiple sets, aerobic, anaerobic
Tujuan penelitian ini adalah untuk mengetahui: (1) perbedaan pengaruh latihan beban menggunakan s... more Tujuan penelitian ini adalah untuk mengetahui: (1) perbedaan pengaruh latihan beban menggunakan sistem single set dan multiple sets terhadap peningkatan daya tahan anaerobik, (2) perbedaan antara pemain sepak bola yang memiliki daya tahan aerobik tinggi dan rendah terhadap peningkatan daya tahan anaerobik, dan (3) interaksi antara metode latihan beban dan daya tahan aerobik dalam meningkatkan daya tahan anaerobik. Penelitian ini menggunakan metode eksperimen dengan rancangan desain faktorial 2x2. Teknik analisis data menggunakan analisis varian (anava) pada taraf signifikansi (α) 0.05. Populasi dalam penelitian ini adalah pemain PS FKIP UNIB yang berjumlah 33 orang. Teknik pengambilan sampel menggunakan purposive sampling dengan jumlah sampel sebanyak 18 atlet. Instrumen dalam penelitian ini adalah tes daya tahan aerobik dengan cooper test dan daya tahan anaerobik dengan running-based anaerobic sprint test. Hasil penelitian menunjukkan: (1) terdapat pengaruh yang signifikan antara l...
The appearance of myofibroblasts is hallmark of fibrosis and tissue repair. Myofibroblasts are st... more The appearance of myofibroblasts is hallmark of fibrosis and tissue repair. Myofibroblasts are stromal cells that transition from fibroblastic progenitors by acquiring new contractile function. Platelet-derived growth factor (PDGF) promotes fibrosis and supports tissue repair, but the relationship between PDGF and the myofibroblast phenotype is unclear. Using mice with PDGF receptor α (PDGFRα) gene activation or deletion and mutation-linked lineage tracing, we examine fibroblastic progenitor cell fate during spontaneous fibrosis and wound-induced fibrosis. Unexpectedly, elevated PDGFRα signaling generates fibrosis while inhibiting myofibroblast formation. Non-canonical TGFβ-p38 signaling is blocked by PDGFRα activity, thereby inhibiting myofibroblasts. However, deletion of PDGFRα also inhibits myofibroblasts by reducing SRF activity, which leads to defective wound repair. Our findings suggest a scenario where PDGFRα initially expands the progenitor population for tissue repair and later suppression of PDGFRα in activated progenitors permits their transition to myofibroblast.
the aim of this research was to understand the effects of weight training method with the use of ... more the aim of this research was to understand the effects of weight training method with the use of single set and multiple sets system and aerobic endurance in improving anaerobic endurance. This research made use of experimental method of 2x2 factorial design. The population in this study were 33 football players of PS FKIP UNIB. Purposive sampling technique was employed in this study and 18 people participated. The instruments used in this study were aerobic endurance tests through the use of Cooper test as well as anaerobic endurance through the use of running-based anaerobic sprint test. The result revealed that weight training with multiple sets system was more significant in increasing anaerobic endurance rather than exercises with single set system. Keywords—weight training, single set, multiple sets, aerobic, anaerobic
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