Journal of the American Academy of Child and Adolescent Psychiatry, 2017
There is a largely unmet need for evidence-based interventions that reduce future aggression and ... more There is a largely unmet need for evidence-based interventions that reduce future aggression and incarceration in clinically aggressive juvenile offenders serving probation. We addressed this gap using a group randomized controlled trial. Offenders both with and without clinical aggression were included, enabling comparison of intervention effects. Juveniles 13 to 17 years old (N = 310, mean = 16 years, 90% African-American, 66% male) on probation were assigned to a 2-week intervention targeting psychosocial factors implicated in risky behavior (e.g., learning strategies to manage "hot" emotions that prompt risk taking) or to an equally intensive health promotion control. Participants completed aggression measures at baseline, 6-, and 12-month follow-up and reported on incarceration at 12 months. Spline regression tested symptom change. Among clinically aggressive offenders (n = 71), the intervention arm showed significantly greater reductions in aggression over the first ...
Neuroticism has been associated with depression and anxiety both cross-sectionally and longitudin... more Neuroticism has been associated with depression and anxiety both cross-sectionally and longitudinally. Interpretive bias has been associated with depression and anxiety, primarily in cross-sectional and bias induction studies. The purpose of the current study was to examine the role of interpretive bias as a prospective risk factor and a mediator of the relation between neuroticism and depressive and anxious symptoms in young adults assessed longitudinally. Neuroticism significantly predicted a broad general distress dimension, but not intermediate fears and anhedonia-apprehension dimensions, nor a narrow social fears dimension. Neuroticism also significantly predicted negative interpretive bias for social scenarios. Negative interpretive bias for social scenarios did not significantly predict dimension scores, nor did it mediate the relation between neuroticism and general distress or social fears. These results suggest that although neuroticism relates to negative interpretive bias, its risk for symptoms of depression and anxiety is at most weakly conferred through negative interpretive bias.
The past decades of research on predictors of depression have frequently emphasized interactive d... more The past decades of research on predictors of depression have frequently emphasized interactive diathesis-stress questions: What kinds of vulnerabilities under stressful circumstances increase risk of developing depression? This study addresses 3 theoretically important gaps in our knowledge regarding diathesis-stress models of depression: the role of temperament (neuroticism), interactive versus additive effects of neuroticism-stress relationships, and effects of stressor characteristics (acute vs. chronic, major vs. minor events, interpersonal vs. noninterpersonal content). We addressed these gaps in the prediction of major depressive episodes (MDEs) in a sample of high schoolers (n = 559) oversampled for high neuroticism and assessed for presence of MDEs annually for 5 years. Survival analyses provided relatively consistent support for the main effects of the broad vulnerability factor of the general neuroticism factor, acute stressors, and chronic stressors in the prediction of MDEs. In contrast, the majority of our analyses failed to support interactive neuroticism-stress accounts of MDE risk. Integrating our results with the extant literature reinforces the notion that both the general neuroticism factor and stress prospectively predict depressive disorders and highlight that their main effects are significantly larger than their interaction. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of differ... more Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of different characteristics of adversity remains unknown. In this study, we examine how developmental timing (childhood vs. adolescence), severity (major vs. minor), and domain of early life adversity relate to diurnal cortisol rhythms in late adolescence. We assessed adversity retrospectively in early adulthood in a subsample of 236 participants from a longitudinal study of a diverse community sample of suburban adolescents oversampled for high neuroticism. We used multilevel modeling to assess associations between our adversity measures and the diurnal cortisol rhythm (waking and bedtime cortisol, awakening response, slope, and average cortisol). Major childhood adversities were associated with flatter daily slope, and minor adolescent adversities were associated with greater average daily cortisol. Examining domains of childhood adversities, major neglect and sexual abuse were associated with flatter slope and lower waking cortisol, with sexual abuse also associated with higher cortisol awakening response. Major physical abuse was associated with higher waking cortisol. Among adolescent adversities domains, minor neglect, emotional abuse, and witnessing violence were associated with greater average cortisol. These results suggest severity, developmental timing, and domain of adversity influence the association of early life adversity with stress response system functioning.
The present study examines the longitudinal association between cortisol (dys)regulation - mean c... more The present study examines the longitudinal association between cortisol (dys)regulation - mean cortisol awakening response (CAR) and area under the curve with respect to ground (AUCg) for total daily cortisol - and autobiographical memory. 135 participants (mean age at baseline = 16.1; Females = 78.5%) provided cortisol samples (T1). Seven months later participants retrieved autobiographical memories cued by positive and negative words (T2). Four years subsequently, participants provided cortisol samples again (T3). The retrieval of more specific memories cued by positive words, but not negative words, was associated with higher AUCg four years later, independent of sex, recent life stressors and self-reported negative self-related cognitions. There were no associations between CAR and autobiographical memory. Neither AUC nor CAR at T1 predicted subsequent autobiographical memory abilities. People who retrieve more positive specific memories may be more likely to imagine and seek out positive experiences and this may be associated with higher cortisol levels.
INTRODUCTION The high rate of comorbidity between alcohol use and emotional disorders is well dem... more INTRODUCTION The high rate of comorbidity between alcohol use and emotional disorders is well demonstrated, but the mechanisms underlying their relationship remain largely unidentified. One possibility is maladaptive responding to negative affect, such as worry and rumination. The present study sought to examine worry and rumination as putative mediators explaining the link between emotional disorders and alcohol use disorders. Methods Mediational analyses were conducted using a sample (n = 232) derived from a larger late adolescence/early adulthood longitudinal dataset (Youth Emotion Project; Zinbarg et al., 2010). Results A significant indirect effect was observed for emotional disorder severity on alcohol use disorder severity via rumination, but not via worry or the shared variance between worry and rumination. Conclusions These findings suggest that rumination may specifically confer risk for the development of alcohol use disorder for individuals with emotional disorders. Further, ruminative thinking may serve as a specific treatment target to reduce vulnerability to alcohol use disorder.
IntroductionDepression and anxiety are implicated in suicide risk, but the contributionof specifi... more IntroductionDepression and anxiety are implicated in suicide risk, but the contributionof specific symptom dimensions within these disorders is not well understood. The present study examined longitudinal associations of transdiagnostic symptoms (General Distress[GD]) and unique symptom dimensions (Anhedonia–Apprehension [AA], Fears, and Narrow Depression [ND]) of depression and anxiety and suicidal ideation (SI).MethodsData from 551 adolescents oversampled on high neuroticism were examined in a series of discrete‐time survival analyses to predict first SI onset over an 8‐year period.ResultsResults indicate that GD, AA, and ND were independent predictors of increased likelihood of SI onset and remained significant when controlling for effects of fears. Furthermore, AA and GD remained significant when controlling for one another. ND effects reduced by 24% when adjusting for AA and 74% when adjusting for GD. Fears did not significantly predict SI onset.ConclusionResults suggest that b...
Negative or stressful life events are robust risk factors for depression and anxiety. Less attent... more Negative or stressful life events are robust risk factors for depression and anxiety. Less attention has been paid to the positive aspects of events and whether positivity buffers the impact of the negative aspects of events. In this study, we examined the positivity and negativity of interpersonal and noninterpersonal episodic life events in predicting anxiety and depressive symptoms in a sample of 373 young adults. Regressions tested the main and interactive effects of positivity and negativity ratings of events in predicting symptom factors (fears, anhedonia-apprehension, general distress) relevant to anxiety and depression. A significant interaction demonstrated that positivity protected against high levels of negativity of noninterpersonal events in predicting general distress. A main effect of interpersonal negativity predicting higher anhedonia-apprehension was observed. Results for fears were nonsignificant. Findings suggest that the positivity of life events may buffer agai...
Early-life adversity is a major risk factor for psychopathology, but not all who experience adver... more Early-life adversity is a major risk factor for psychopathology, but not all who experience adversity develop psychopathology. The current study evaluated whether the links between child and adolescent adversity and depression and anxiety were described by general benefits and/or buffering effects of interpersonal support. Data from 456 adolescents oversampled on neuroticism over a 5-year period were examined in a series of discrete-time survival analyses to predict subsequent disorder onsets. Models examined linear, quadratic, and interactive effects of interpersonal support over time, as measured by chronic interpersonal stress interview ratings. Results did not support buffering effects of interpersonal support against either child or adolescent adversity in predicting depression or anxiety. However, there was support for the general benefits model of interpersonal support as evidenced by follow-up analyses of significant quadratic effects of interpersonal support, demonstrating ...
Whereas there is extensive research on factors that contribute to vulnerability for depression an... more Whereas there is extensive research on factors that contribute to vulnerability for depression and anxiety, research on how to promote mental health or offset risk effects in individuals likely to develop these disorders is lacking. Resilience models focus on risk, resource, and protective factors and their relationships. The current longitudinal study evaluated whether extraversion and interpersonal support functioned in resource or protective roles in relation to unipolar mood disorder (UMD), anxiety disorder (AD), and comorbid diagnoses. Data from 534 adolescents over a 3-year period were examined in a series of survival analyses to predict future disorder onset. The linear effect of extraversion significantly interacted with neuroticism predicting UMD diagnoses with extraversion conferring protection and introversion conferring risk at high levels of neuroticism. The quadratic effect of extraversion significantly interacted with neuroticism predicting AD and comorbid diagnoses such that extraversion escalated risk for diagnoses at high levels of neuroticism. The quadratic effect of extraversion was significant in comorbidity models, demonstrating increased risk as one progresses from slight extraversion to extreme introversion, independent of neuroticism. Interpersonal support significantly predicted UMD, AD, and comorbid diagnoses in an approximately linear fashion. Specificity tests indicated that these effects remained when including the other diagnosis in each model. Findings suggest the value of attending to extraverted traits and encouraging social connection regardless of risk status in prevention and treatment approaches. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Research has demonstrated that stressors play a critical role in the development of generalized a... more Research has demonstrated that stressors play a critical role in the development of generalized anxiety disorder (GAD), social anxiety disorder (SAD), and major depressive disorder (MDD). Separately, deficits in positive affect (PA) have been identified in GAD, SAD, and MDD. Whereas previous research has linked the buffering effects of PA in chronic illness, such effects have yet to be investigated for chronic stressors and emotional disorder–related symptom severity. The purpose of the present study was to examine PA as a moderator of chronic interpersonal and noninterpersonal stress on GAD, SAD, and MDD symptom severity. Using a multilevel statistical approach with a sample of adolescents and young adults ( N = 463), PA was found to moderate significantly the relationship between chronic interpersonal stress and symptom severity for MDD and SAD. Findings suggest that in times of chronic interpersonal stress, higher PA may serve as a buffer from development of SAD and MDD symptoms.
Neuroticism and several other traits have been proposed to confer vulnerability for unipolar mood... more Neuroticism and several other traits have been proposed to confer vulnerability for unipolar mood disorders (UMDs) and anxiety disorders (ADs). However, it is unclear whether the associations of these vulnerabilities with these disorders are attributable to a latent variable common to all vulnerabilities, more narrow latent variables, or both. In addition, some researchers have suggested that neuroticism predicts UMDs, ADs, and substance use disorders (SUDs) with comparable strength, whereas other researchers have hypothesized that neuroticism is more strongly related to UMDs and ADs. We tested hypotheses about the factor structure of several vulnerabilities and the prospective associations of these latent variables with initial onsets of UMDs, ADs, and SUDs during a 3-year period in 547 participants recruited as high school juniors. Although a general neuroticism factor predicted SUDs, it predicted UMDs and ADs more strongly and especially predicted comorbid UMDs and ADs. There was...
This study compared a series of higher-order models encompassing symptoms of both clinical and pe... more This study compared a series of higher-order models encompassing symptoms of both clinical and personality disorders. The final model was then correlated with a latent variable model of normal personality traits. A total of 420 undergraduates completed a battery of self-report symptom and personality questionnaires, with informant-reports and diagnostic interviews provided by overlapping subsamples. A three-level model with two factors at the highest level and four factors at the second level was the best fitting model. The higher-order internalizing and externalizing factors were then correlated with 30 latent personality facets. Results demonstrate an elevation on the neuroticism facets for the higher-order internalizing factor, along with low positive emotions, low actions, and low competence. The higher-order externalizing factor was negatively associated with most conscientiousness and agreeableness factors, while showing an elevation on excitement-seeking, impulsivity, and angry hostility. Future studies should replicate these models with the inclusion of more low base-rate disorders (i.e., psychosis).
Considerable debate surrounds the question of whether psychopathology can be meaningfully studied... more Considerable debate surrounds the question of whether psychopathology can be meaningfully studied in animals. On one side of the debate is the argument that psychopathological syndromes such as anxiety and depression are uniquely human, i.e., that animals cannot experience such states. A corollary to this argument is that systematic study of emotional or disturbed behavior in animals will not be of use in understanding human psychopathology. On the other side of the debate is the argument that there are naturally occurring syndromes in some higher animals that closely parallel those observed in human psychopathology. The corollary to this argument is that there is much to be learned from the systematic study of emotional or disturbed behavior in those animals. Proponents of the later argument would contend that any problems created by potential differences between the species are more than offset by the advantages stemming from the ability to study the animals in highly controlled conditions over prolonged periods of time (cf. Abramson & Seligman, 1977).
Journal of the American Academy of Child and Adolescent Psychiatry, 2017
There is a largely unmet need for evidence-based interventions that reduce future aggression and ... more There is a largely unmet need for evidence-based interventions that reduce future aggression and incarceration in clinically aggressive juvenile offenders serving probation. We addressed this gap using a group randomized controlled trial. Offenders both with and without clinical aggression were included, enabling comparison of intervention effects. Juveniles 13 to 17 years old (N = 310, mean = 16 years, 90% African-American, 66% male) on probation were assigned to a 2-week intervention targeting psychosocial factors implicated in risky behavior (e.g., learning strategies to manage "hot" emotions that prompt risk taking) or to an equally intensive health promotion control. Participants completed aggression measures at baseline, 6-, and 12-month follow-up and reported on incarceration at 12 months. Spline regression tested symptom change. Among clinically aggressive offenders (n = 71), the intervention arm showed significantly greater reductions in aggression over the first ...
Neuroticism has been associated with depression and anxiety both cross-sectionally and longitudin... more Neuroticism has been associated with depression and anxiety both cross-sectionally and longitudinally. Interpretive bias has been associated with depression and anxiety, primarily in cross-sectional and bias induction studies. The purpose of the current study was to examine the role of interpretive bias as a prospective risk factor and a mediator of the relation between neuroticism and depressive and anxious symptoms in young adults assessed longitudinally. Neuroticism significantly predicted a broad general distress dimension, but not intermediate fears and anhedonia-apprehension dimensions, nor a narrow social fears dimension. Neuroticism also significantly predicted negative interpretive bias for social scenarios. Negative interpretive bias for social scenarios did not significantly predict dimension scores, nor did it mediate the relation between neuroticism and general distress or social fears. These results suggest that although neuroticism relates to negative interpretive bias, its risk for symptoms of depression and anxiety is at most weakly conferred through negative interpretive bias.
The past decades of research on predictors of depression have frequently emphasized interactive d... more The past decades of research on predictors of depression have frequently emphasized interactive diathesis-stress questions: What kinds of vulnerabilities under stressful circumstances increase risk of developing depression? This study addresses 3 theoretically important gaps in our knowledge regarding diathesis-stress models of depression: the role of temperament (neuroticism), interactive versus additive effects of neuroticism-stress relationships, and effects of stressor characteristics (acute vs. chronic, major vs. minor events, interpersonal vs. noninterpersonal content). We addressed these gaps in the prediction of major depressive episodes (MDEs) in a sample of high schoolers (n = 559) oversampled for high neuroticism and assessed for presence of MDEs annually for 5 years. Survival analyses provided relatively consistent support for the main effects of the broad vulnerability factor of the general neuroticism factor, acute stressors, and chronic stressors in the prediction of MDEs. In contrast, the majority of our analyses failed to support interactive neuroticism-stress accounts of MDE risk. Integrating our results with the extant literature reinforces the notion that both the general neuroticism factor and stress prospectively predict depressive disorders and highlight that their main effects are significantly larger than their interaction. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of differ... more Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of different characteristics of adversity remains unknown. In this study, we examine how developmental timing (childhood vs. adolescence), severity (major vs. minor), and domain of early life adversity relate to diurnal cortisol rhythms in late adolescence. We assessed adversity retrospectively in early adulthood in a subsample of 236 participants from a longitudinal study of a diverse community sample of suburban adolescents oversampled for high neuroticism. We used multilevel modeling to assess associations between our adversity measures and the diurnal cortisol rhythm (waking and bedtime cortisol, awakening response, slope, and average cortisol). Major childhood adversities were associated with flatter daily slope, and minor adolescent adversities were associated with greater average daily cortisol. Examining domains of childhood adversities, major neglect and sexual abuse were associated with flatter slope and lower waking cortisol, with sexual abuse also associated with higher cortisol awakening response. Major physical abuse was associated with higher waking cortisol. Among adolescent adversities domains, minor neglect, emotional abuse, and witnessing violence were associated with greater average cortisol. These results suggest severity, developmental timing, and domain of adversity influence the association of early life adversity with stress response system functioning.
The present study examines the longitudinal association between cortisol (dys)regulation - mean c... more The present study examines the longitudinal association between cortisol (dys)regulation - mean cortisol awakening response (CAR) and area under the curve with respect to ground (AUCg) for total daily cortisol - and autobiographical memory. 135 participants (mean age at baseline = 16.1; Females = 78.5%) provided cortisol samples (T1). Seven months later participants retrieved autobiographical memories cued by positive and negative words (T2). Four years subsequently, participants provided cortisol samples again (T3). The retrieval of more specific memories cued by positive words, but not negative words, was associated with higher AUCg four years later, independent of sex, recent life stressors and self-reported negative self-related cognitions. There were no associations between CAR and autobiographical memory. Neither AUC nor CAR at T1 predicted subsequent autobiographical memory abilities. People who retrieve more positive specific memories may be more likely to imagine and seek out positive experiences and this may be associated with higher cortisol levels.
INTRODUCTION The high rate of comorbidity between alcohol use and emotional disorders is well dem... more INTRODUCTION The high rate of comorbidity between alcohol use and emotional disorders is well demonstrated, but the mechanisms underlying their relationship remain largely unidentified. One possibility is maladaptive responding to negative affect, such as worry and rumination. The present study sought to examine worry and rumination as putative mediators explaining the link between emotional disorders and alcohol use disorders. Methods Mediational analyses were conducted using a sample (n = 232) derived from a larger late adolescence/early adulthood longitudinal dataset (Youth Emotion Project; Zinbarg et al., 2010). Results A significant indirect effect was observed for emotional disorder severity on alcohol use disorder severity via rumination, but not via worry or the shared variance between worry and rumination. Conclusions These findings suggest that rumination may specifically confer risk for the development of alcohol use disorder for individuals with emotional disorders. Further, ruminative thinking may serve as a specific treatment target to reduce vulnerability to alcohol use disorder.
IntroductionDepression and anxiety are implicated in suicide risk, but the contributionof specifi... more IntroductionDepression and anxiety are implicated in suicide risk, but the contributionof specific symptom dimensions within these disorders is not well understood. The present study examined longitudinal associations of transdiagnostic symptoms (General Distress[GD]) and unique symptom dimensions (Anhedonia–Apprehension [AA], Fears, and Narrow Depression [ND]) of depression and anxiety and suicidal ideation (SI).MethodsData from 551 adolescents oversampled on high neuroticism were examined in a series of discrete‐time survival analyses to predict first SI onset over an 8‐year period.ResultsResults indicate that GD, AA, and ND were independent predictors of increased likelihood of SI onset and remained significant when controlling for effects of fears. Furthermore, AA and GD remained significant when controlling for one another. ND effects reduced by 24% when adjusting for AA and 74% when adjusting for GD. Fears did not significantly predict SI onset.ConclusionResults suggest that b...
Negative or stressful life events are robust risk factors for depression and anxiety. Less attent... more Negative or stressful life events are robust risk factors for depression and anxiety. Less attention has been paid to the positive aspects of events and whether positivity buffers the impact of the negative aspects of events. In this study, we examined the positivity and negativity of interpersonal and noninterpersonal episodic life events in predicting anxiety and depressive symptoms in a sample of 373 young adults. Regressions tested the main and interactive effects of positivity and negativity ratings of events in predicting symptom factors (fears, anhedonia-apprehension, general distress) relevant to anxiety and depression. A significant interaction demonstrated that positivity protected against high levels of negativity of noninterpersonal events in predicting general distress. A main effect of interpersonal negativity predicting higher anhedonia-apprehension was observed. Results for fears were nonsignificant. Findings suggest that the positivity of life events may buffer agai...
Early-life adversity is a major risk factor for psychopathology, but not all who experience adver... more Early-life adversity is a major risk factor for psychopathology, but not all who experience adversity develop psychopathology. The current study evaluated whether the links between child and adolescent adversity and depression and anxiety were described by general benefits and/or buffering effects of interpersonal support. Data from 456 adolescents oversampled on neuroticism over a 5-year period were examined in a series of discrete-time survival analyses to predict subsequent disorder onsets. Models examined linear, quadratic, and interactive effects of interpersonal support over time, as measured by chronic interpersonal stress interview ratings. Results did not support buffering effects of interpersonal support against either child or adolescent adversity in predicting depression or anxiety. However, there was support for the general benefits model of interpersonal support as evidenced by follow-up analyses of significant quadratic effects of interpersonal support, demonstrating ...
Whereas there is extensive research on factors that contribute to vulnerability for depression an... more Whereas there is extensive research on factors that contribute to vulnerability for depression and anxiety, research on how to promote mental health or offset risk effects in individuals likely to develop these disorders is lacking. Resilience models focus on risk, resource, and protective factors and their relationships. The current longitudinal study evaluated whether extraversion and interpersonal support functioned in resource or protective roles in relation to unipolar mood disorder (UMD), anxiety disorder (AD), and comorbid diagnoses. Data from 534 adolescents over a 3-year period were examined in a series of survival analyses to predict future disorder onset. The linear effect of extraversion significantly interacted with neuroticism predicting UMD diagnoses with extraversion conferring protection and introversion conferring risk at high levels of neuroticism. The quadratic effect of extraversion significantly interacted with neuroticism predicting AD and comorbid diagnoses such that extraversion escalated risk for diagnoses at high levels of neuroticism. The quadratic effect of extraversion was significant in comorbidity models, demonstrating increased risk as one progresses from slight extraversion to extreme introversion, independent of neuroticism. Interpersonal support significantly predicted UMD, AD, and comorbid diagnoses in an approximately linear fashion. Specificity tests indicated that these effects remained when including the other diagnosis in each model. Findings suggest the value of attending to extraverted traits and encouraging social connection regardless of risk status in prevention and treatment approaches. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Research has demonstrated that stressors play a critical role in the development of generalized a... more Research has demonstrated that stressors play a critical role in the development of generalized anxiety disorder (GAD), social anxiety disorder (SAD), and major depressive disorder (MDD). Separately, deficits in positive affect (PA) have been identified in GAD, SAD, and MDD. Whereas previous research has linked the buffering effects of PA in chronic illness, such effects have yet to be investigated for chronic stressors and emotional disorder–related symptom severity. The purpose of the present study was to examine PA as a moderator of chronic interpersonal and noninterpersonal stress on GAD, SAD, and MDD symptom severity. Using a multilevel statistical approach with a sample of adolescents and young adults ( N = 463), PA was found to moderate significantly the relationship between chronic interpersonal stress and symptom severity for MDD and SAD. Findings suggest that in times of chronic interpersonal stress, higher PA may serve as a buffer from development of SAD and MDD symptoms.
Neuroticism and several other traits have been proposed to confer vulnerability for unipolar mood... more Neuroticism and several other traits have been proposed to confer vulnerability for unipolar mood disorders (UMDs) and anxiety disorders (ADs). However, it is unclear whether the associations of these vulnerabilities with these disorders are attributable to a latent variable common to all vulnerabilities, more narrow latent variables, or both. In addition, some researchers have suggested that neuroticism predicts UMDs, ADs, and substance use disorders (SUDs) with comparable strength, whereas other researchers have hypothesized that neuroticism is more strongly related to UMDs and ADs. We tested hypotheses about the factor structure of several vulnerabilities and the prospective associations of these latent variables with initial onsets of UMDs, ADs, and SUDs during a 3-year period in 547 participants recruited as high school juniors. Although a general neuroticism factor predicted SUDs, it predicted UMDs and ADs more strongly and especially predicted comorbid UMDs and ADs. There was...
This study compared a series of higher-order models encompassing symptoms of both clinical and pe... more This study compared a series of higher-order models encompassing symptoms of both clinical and personality disorders. The final model was then correlated with a latent variable model of normal personality traits. A total of 420 undergraduates completed a battery of self-report symptom and personality questionnaires, with informant-reports and diagnostic interviews provided by overlapping subsamples. A three-level model with two factors at the highest level and four factors at the second level was the best fitting model. The higher-order internalizing and externalizing factors were then correlated with 30 latent personality facets. Results demonstrate an elevation on the neuroticism facets for the higher-order internalizing factor, along with low positive emotions, low actions, and low competence. The higher-order externalizing factor was negatively associated with most conscientiousness and agreeableness factors, while showing an elevation on excitement-seeking, impulsivity, and angry hostility. Future studies should replicate these models with the inclusion of more low base-rate disorders (i.e., psychosis).
Considerable debate surrounds the question of whether psychopathology can be meaningfully studied... more Considerable debate surrounds the question of whether psychopathology can be meaningfully studied in animals. On one side of the debate is the argument that psychopathological syndromes such as anxiety and depression are uniquely human, i.e., that animals cannot experience such states. A corollary to this argument is that systematic study of emotional or disturbed behavior in animals will not be of use in understanding human psychopathology. On the other side of the debate is the argument that there are naturally occurring syndromes in some higher animals that closely parallel those observed in human psychopathology. The corollary to this argument is that there is much to be learned from the systematic study of emotional or disturbed behavior in those animals. Proponents of the later argument would contend that any problems created by potential differences between the species are more than offset by the advantages stemming from the ability to study the animals in highly controlled conditions over prolonged periods of time (cf. Abramson & Seligman, 1977).
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Papers by Richard Zinbarg