Abstract Melanotic neuroectodermal tumour of infancy (MNETI) is a rare benign pigmented neoplasm ... more Abstract Melanotic neuroectodermal tumour of infancy (MNETI) is a rare benign pigmented neoplasm of neural crest origin that commonly presents during the first year of life. Typically the tumour presents in the head and neck region, with the alveolar crest of the maxilla being the most commonly affected site. MNETI presents as an expansile pigmented mass that is characterized by aggressive growth pattern and high recurrence rate. The lack of strong evidence-based approaches to management stems from the rarity of this condition. We report on MNETI in a 2-months-old infant who presented with a maxillary lesion which was treated by partial maxillectomy following recurrence after primary conservative treatment. The lesion resolved without evidence of relapse 12 months later.
Aim: To evaluate the benefits of a long-term prophylactic antibiotic regimen following treatment ... more Aim: To evaluate the benefits of a long-term prophylactic antibiotic regimen following treatment of fractured mandibles with open reduction and internal fixation. Material and Methods: A prospective, randomized controlled trial was undertaken at Wits Oral Health Centre. Patients with mandibular fractures who were managed with open reduction and internal fixation using miniplates were randomized into 2 groups. The control group, the perioperative antibiotic (POA) group, was composed of patients who received intravenous (IV) antibiotic cover intraoperatively and a further 3 IV doses 24 hours postoperatively. The study group, the extended postoperative antibiotic (EPOA), was composed of patients who received similar doses as the control group but with an additional 5 days of oral antibiotics upon discharge. The patients were then evaluated for evidence of infection 1, 4, and 6 weeks postoperatively. Results: A total of 77 patients were included in the study, 41 in the POA and 36 in the...
Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports a... more Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.
Kaposiform Hemangio-endothelioma (KHE) is a rare vascular neoplasm of intermediate malignancy tha... more Kaposiform Hemangio-endothelioma (KHE) is a rare vascular neoplasm of intermediate malignancy that generally occurs in infancy and early childhood. Typically, the lesion arises from superficial or deep soft tissues of the extremities, trunk and retroperitoneum. The paucity of reported cases of head and neck KHEs is evidence of the rarity of the disease in this region. We report on the presentation and treatment of KHE in a 11-months-old boy who presented with a mandibular lesion. We include a brief discussion about the differential diagnosis of KHE. Management involved preoperative interventional radiology, surgical excision and chemotherapeutic treatment with Sirolimus. The lesion resolved without evidence of relapse 12 months later.
Ameloblastomas typically occur in adults and are considered a rarity in the pediatric patient pop... more Ameloblastomas typically occur in adults and are considered a rarity in the pediatric patient population. We report on the treatment outcome of a pediatric patient who presented with a unicystic ameloblastoma in the mandible. A 15-year-old boy presented with a large, expansile lesion in the ramus-angle region of the mandible. Incisional biopsy findings confirmed the lesion was a type II unicystic ameloblastoma. Treatment consisted of unroofing of the bone overlying the lesion followed by enucleation with peripheral ostectomy. A 10-mL disposable Luer-lock syringe was cut and modified to fit into the window of the lesion to facilitate irrigation with saline solution. The disposable syringe was held in position with 0.18-mm stainless steel wire for 3 months. Modification of the conservative treatment using the syringe allowed for complete regeneration of bone in the large cavity without the need for bone graft or resection of the lesion. At the 3-year follow-up, there was no sign of recurrence.
Abstract Melanotic neuroectodermal tumour of infancy (MNETI) is a rare benign pigmented neoplasm ... more Abstract Melanotic neuroectodermal tumour of infancy (MNETI) is a rare benign pigmented neoplasm of neural crest origin that commonly presents during the first year of life. Typically the tumour presents in the head and neck region, with the alveolar crest of the maxilla being the most commonly affected site. MNETI presents as an expansile pigmented mass that is characterized by aggressive growth pattern and high recurrence rate. The lack of strong evidence-based approaches to management stems from the rarity of this condition. We report on MNETI in a 2-months-old infant who presented with a maxillary lesion which was treated by partial maxillectomy following recurrence after primary conservative treatment. The lesion resolved without evidence of relapse 12 months later.
Aim: To evaluate the benefits of a long-term prophylactic antibiotic regimen following treatment ... more Aim: To evaluate the benefits of a long-term prophylactic antibiotic regimen following treatment of fractured mandibles with open reduction and internal fixation. Material and Methods: A prospective, randomized controlled trial was undertaken at Wits Oral Health Centre. Patients with mandibular fractures who were managed with open reduction and internal fixation using miniplates were randomized into 2 groups. The control group, the perioperative antibiotic (POA) group, was composed of patients who received intravenous (IV) antibiotic cover intraoperatively and a further 3 IV doses 24 hours postoperatively. The study group, the extended postoperative antibiotic (EPOA), was composed of patients who received similar doses as the control group but with an additional 5 days of oral antibiotics upon discharge. The patients were then evaluated for evidence of infection 1, 4, and 6 weeks postoperatively. Results: A total of 77 patients were included in the study, 41 in the POA and 36 in the...
Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports a... more Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.
Kaposiform Hemangio-endothelioma (KHE) is a rare vascular neoplasm of intermediate malignancy tha... more Kaposiform Hemangio-endothelioma (KHE) is a rare vascular neoplasm of intermediate malignancy that generally occurs in infancy and early childhood. Typically, the lesion arises from superficial or deep soft tissues of the extremities, trunk and retroperitoneum. The paucity of reported cases of head and neck KHEs is evidence of the rarity of the disease in this region. We report on the presentation and treatment of KHE in a 11-months-old boy who presented with a mandibular lesion. We include a brief discussion about the differential diagnosis of KHE. Management involved preoperative interventional radiology, surgical excision and chemotherapeutic treatment with Sirolimus. The lesion resolved without evidence of relapse 12 months later.
Ameloblastomas typically occur in adults and are considered a rarity in the pediatric patient pop... more Ameloblastomas typically occur in adults and are considered a rarity in the pediatric patient population. We report on the treatment outcome of a pediatric patient who presented with a unicystic ameloblastoma in the mandible. A 15-year-old boy presented with a large, expansile lesion in the ramus-angle region of the mandible. Incisional biopsy findings confirmed the lesion was a type II unicystic ameloblastoma. Treatment consisted of unroofing of the bone overlying the lesion followed by enucleation with peripheral ostectomy. A 10-mL disposable Luer-lock syringe was cut and modified to fit into the window of the lesion to facilitate irrigation with saline solution. The disposable syringe was held in position with 0.18-mm stainless steel wire for 3 months. Modification of the conservative treatment using the syringe allowed for complete regeneration of bone in the large cavity without the need for bone graft or resection of the lesion. At the 3-year follow-up, there was no sign of recurrence.
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