Centella asiatica (L.) Urban (C. asiatica) is a medicinal plant that generates terpenes, phenols,... more Centella asiatica (L.) Urban (C. asiatica) is a medicinal plant that generates terpenes, phenols, vitamins, minerals, polyacetylene and fatty acids among other phyto-constituents. This review focuses on the bibliometric analysis of 1164 documents on C. asiatica that were retrieved from the Scopus database. Harzing Publish or Perish and VOSviewer were used for citation and network analyses. According to the bibliometric analysis, publications are on the rise, particularly in the fields of pharmacology, toxicology and pharmaceutics, medicine, biochemistry, genetics and molecular biology, agricultural and biological sciences, and chemistry. "Phytoremediation", "secondary metabolites", "Andrographis paniculata", and "cognitive impairment" are emerging areas for C. asiatica research. However, currently there is a lack of international collaboration in C. asiatica research among contributing countries. Researchers can utilise the findings cited in this reiew to locate potential collaborators, top authors, countries and documents.
Background: Diabetes mellitus is a group of metabolic disorders sharing the common underlying fea... more Background: Diabetes mellitus is a group of metabolic disorders sharing the common underlying feature of hyperglycemia. In developed countries, use of medicinal plants has recently increased as scientific evidence about their effectiveness has become broadly available. This article is to review the efficacy and safety of medicinal plants commonly used for diabetes mellitus. Materials and Methods: We carried out a literature search in several electronic data bases such as: Pubmed, Pubmed Central, Google, Google Scholar, Scopus and Medline from 2000 to 2020 to acquire the status of information concerning this concept. Results: Medicinal plants have long been used in traditional systems of medicine for diabetes. Some recent reports on the medicinal plant with anti-diabetic effects have provided evidence for possible mechanisms of action. Nonetheless, the majority of investigators only speculated on a wide range of possible mechanisms or simply demonstrated an antihyperglycemic effect f...
INTRODUCTION Inflammation plays a central role in the pathogenesis of cardiovascular events. The ... more INTRODUCTION Inflammation plays a central role in the pathogenesis of cardiovascular events. The lack of exercise among Malaysians and the increasing cardiovascular diseases among young men are of concern. The aim of this study was to evaluate the reducing of inflammation by measuring C-Reactive protein (CRP), interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α). MATERIALS AND METHODS A total of 70 young men (20 - 40 years) who were sedentary, achieving less than 5,000 steps/day in casual walking with 2 or more cardiovascular risk factors were recruited in Institute of Vocational Skills for Youth (IKBN Hulu Langat). Subjects were randomly assigned to a control group (CG) (n=34; no change in walking) and pedometer group (PG) (n=36; minimum target: 8,000 steps/day). All parameter was measured at baseline, at 6 weeks and after 12 weeks. RESULTS At post intervention, the CG step counts were similar (4983 ± 366vs 5697 ± 407steps/day). The PG significant increased step count from...
This review aims to perform a bibliometric analysis of the research related to brain-derived neur... more This review aims to perform a bibliometric analysis of the research related to brain-derived neurotrophic factor (BDNF) in schizophrenia and offer suggestions for further work. Based on the keywords used, our study retrieved 335 documents for further analysis using a combination of three bibliometric techniques: co-word analysis, document co-citation analysis, and bibliographic coupling. A general rising trend in the number of publications was found in BDNF and schizophrenia research. Researchers from China and the United States have mostly researched BDNF and schizophrenia. Molecular Psychiatry is the most prestigious journal in the field of BDNF and schizophrenia research. The main topics and important research areas are cognition and the involvement of BDNF as a neurobiological marker (pathogenesis, therapy monitoring, and risk factors). Future research is anticipated to concentrate on relevant subjects, such as factors that affect BDNF levels or are connected to BDNF dysfunction...
European Journal of Integrative Medicine, Aug 1, 2013
ABSTRACT Introduction The effects of honey administration during normal pregnancy and prenatal st... more ABSTRACT Introduction The effects of honey administration during normal pregnancy and prenatal stress on pain behavior in the offspring are not known. Here we examined the effects of Tualang honey administration during pregnancy and prenatal stress on pain responses in male rat offspring. Materials and methods Pregnant dams were divided into four groups; control (C), honey (H), stress (S) and stress with honey (SH). Tualang honey (1.2 g/kg) or distilled water was administered orally throughout pregnancy. S and SH groups were subjected to restraining stress from day 11 of pregnancy until delivery. Intraplantar formalin injection and thermal stimulus were given to the male adult offspring (220–300 g). Behavior data due to formalin injection and thermal stimuli were analyzed using repeated measures analysis of variance (ANOVA) and one way ANOVA respectively and significance level was taken as less than 0.05. Results The study showed that the offspring from the H group had higher tail flick latency time compared to C and offspring from SH group had a significant reduction in the formalin test score in phase 1 and late phase 2 compared to S group. Discussion The nutrients in Tualang honey are beneficial to support neural development of the fetus and capable to modulate the offspring's nociceptive responses. The present study provides novel knowledge regarding the possible role of Tualang honey in fetal neural development which modulates pain responses in later life. Further studies are required to elucidate the mechanisms of action of honey on pain behavior in the rat offspring.
Centella asiatica (L.) Urban (C. asiatica) is a medicinal plant that generates terpenes, phenols,... more Centella asiatica (L.) Urban (C. asiatica) is a medicinal plant that generates terpenes, phenols, vitamins, minerals, polyacetylene and fatty acids among other phyto-constituents. This review focuses on the bibliometric analysis of 1164 documents on C. asiatica that were retrieved from the Scopus database. Harzing Publish or Perish and VOSviewer were used for citation and network analyses. According to the bibliometric analysis, publications are on the rise, particularly in the fields of pharmacology, toxicology and pharmaceutics, medicine, biochemistry, genetics and molecular biology, agricultural and biological sciences, and chemistry. "Phytoremediation", "secondary metabolites", "Andrographis paniculata", and "cognitive impairment" are emerging areas for C. asiatica research. However, currently there is a lack of international collaboration in C. asiatica research among contributing countries. Researchers can utilise the findings cited in this reiew to locate potential collaborators, top authors, countries and documents.
Background: Diabetes mellitus is a group of metabolic disorders sharing the common underlying fea... more Background: Diabetes mellitus is a group of metabolic disorders sharing the common underlying feature of hyperglycemia. In developed countries, use of medicinal plants has recently increased as scientific evidence about their effectiveness has become broadly available. This article is to review the efficacy and safety of medicinal plants commonly used for diabetes mellitus. Materials and Methods: We carried out a literature search in several electronic data bases such as: Pubmed, Pubmed Central, Google, Google Scholar, Scopus and Medline from 2000 to 2020 to acquire the status of information concerning this concept. Results: Medicinal plants have long been used in traditional systems of medicine for diabetes. Some recent reports on the medicinal plant with anti-diabetic effects have provided evidence for possible mechanisms of action. Nonetheless, the majority of investigators only speculated on a wide range of possible mechanisms or simply demonstrated an antihyperglycemic effect f...
INTRODUCTION Inflammation plays a central role in the pathogenesis of cardiovascular events. The ... more INTRODUCTION Inflammation plays a central role in the pathogenesis of cardiovascular events. The lack of exercise among Malaysians and the increasing cardiovascular diseases among young men are of concern. The aim of this study was to evaluate the reducing of inflammation by measuring C-Reactive protein (CRP), interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α). MATERIALS AND METHODS A total of 70 young men (20 - 40 years) who were sedentary, achieving less than 5,000 steps/day in casual walking with 2 or more cardiovascular risk factors were recruited in Institute of Vocational Skills for Youth (IKBN Hulu Langat). Subjects were randomly assigned to a control group (CG) (n=34; no change in walking) and pedometer group (PG) (n=36; minimum target: 8,000 steps/day). All parameter was measured at baseline, at 6 weeks and after 12 weeks. RESULTS At post intervention, the CG step counts were similar (4983 ± 366vs 5697 ± 407steps/day). The PG significant increased step count from...
This review aims to perform a bibliometric analysis of the research related to brain-derived neur... more This review aims to perform a bibliometric analysis of the research related to brain-derived neurotrophic factor (BDNF) in schizophrenia and offer suggestions for further work. Based on the keywords used, our study retrieved 335 documents for further analysis using a combination of three bibliometric techniques: co-word analysis, document co-citation analysis, and bibliographic coupling. A general rising trend in the number of publications was found in BDNF and schizophrenia research. Researchers from China and the United States have mostly researched BDNF and schizophrenia. Molecular Psychiatry is the most prestigious journal in the field of BDNF and schizophrenia research. The main topics and important research areas are cognition and the involvement of BDNF as a neurobiological marker (pathogenesis, therapy monitoring, and risk factors). Future research is anticipated to concentrate on relevant subjects, such as factors that affect BDNF levels or are connected to BDNF dysfunction...
European Journal of Integrative Medicine, Aug 1, 2013
ABSTRACT Introduction The effects of honey administration during normal pregnancy and prenatal st... more ABSTRACT Introduction The effects of honey administration during normal pregnancy and prenatal stress on pain behavior in the offspring are not known. Here we examined the effects of Tualang honey administration during pregnancy and prenatal stress on pain responses in male rat offspring. Materials and methods Pregnant dams were divided into four groups; control (C), honey (H), stress (S) and stress with honey (SH). Tualang honey (1.2 g/kg) or distilled water was administered orally throughout pregnancy. S and SH groups were subjected to restraining stress from day 11 of pregnancy until delivery. Intraplantar formalin injection and thermal stimulus were given to the male adult offspring (220–300 g). Behavior data due to formalin injection and thermal stimuli were analyzed using repeated measures analysis of variance (ANOVA) and one way ANOVA respectively and significance level was taken as less than 0.05. Results The study showed that the offspring from the H group had higher tail flick latency time compared to C and offspring from SH group had a significant reduction in the formalin test score in phase 1 and late phase 2 compared to S group. Discussion The nutrients in Tualang honey are beneficial to support neural development of the fetus and capable to modulate the offspring's nociceptive responses. The present study provides novel knowledge regarding the possible role of Tualang honey in fetal neural development which modulates pain responses in later life. Further studies are required to elucidate the mechanisms of action of honey on pain behavior in the rat offspring.
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Papers by Rozaziana Ahmad