Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and dive... more Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. In recent years, tularemia cases are increasing in Turkey, with a special attention to Marmara, western Blacksea and Central Anatolia regions. The aim of this study was to evaluate tularemia cases admitted to our hospital during an outbreak emerged at Central Anatolia between December 2009 and September 2010, making a point for the disease. A total of 32 patients (17 female, 15 male; age range: 15-80 years, mean age: 41 ± 16 years) with fever, sore throat, cervical mass and failure to respond to beta-lactam antibiotics, were followed up with the preliminary diagnosis of tularemia. The diagnosis was confirmed by specific laboratory tests. Serum samples were obtained from 25 patients and in 17 (68%) of them microagglutination test yielded positive result (≥ 1/160) in their first serum samples. All of the 8 patients who had negative results in their first sample...
Shortly after the first detection of human immundeficiency virus (HIV) infection in USA in 1981, ... more Shortly after the first detection of human immundeficiency virus (HIV) infection in USA in 1981, the number of cases have increased gradually from all around the world. Turkey’s high capacity for tourism and the unique geographic location extending between Europe and Asia, provides convenience for the passage of individuals across the countries and sexually transmitted infections including HIV, as well. According to the official data of the Ministry of Health; there are 25809 HIV positive and 1958 AIDS cases as of November 30, 2020, after the epidemic started in 1985 in Turkey. Despite the decrease in the number of newly detected HIV cases as a result of serious measures taken for the transmission of infection worldwide, the increase in the number of cases still continues in our country. Shortening the reporting period and starting treatment as soon as possible in the diagnosis of infection is critical for the control of the epidemic. For this purpose, Centers for Disease Control an...
Background Brucellosis is a worldwide zoonotic disease that causes serious public health problems... more Background Brucellosis is a worldwide zoonotic disease that causes serious public health problems. This study aimed to identify Brucella strains isolated from various clinical samples by conventional and molecular methods and to determine antimicrobial susceptibilities against doxycycline (DOX), streptomycin (STR), ciprofloxacin (CIP) and rifampicin (RIF) by the gradient strip (E test) test method. Methods A total of 87 Brucella strains isolated from various clinical specimens between 2004 and 2018 were included in this study. While four of the 87 strains included in the study were identified only at the genus level, the remaining 83 strains were identified at the species level by the Real-Time Multiplex PCR (M-RT-PCR) method and conventional methods were used for biotyping. Results According to molecular identification results, 83 strains were identified as B. melitensis by the M-RT-PCR method, with 82 strains identified as Brucella melitensis biovar (bv) 3 and one as B. melitensis...
Bu calismanin hayvan materyalini, klinigimize derisinde uzun sureli iyilesmeyen yaralar ve kronik... more Bu calismanin hayvan materyalini, klinigimize derisinde uzun sureli iyilesmeyen yaralar ve kronik burun kanamasi sikayetleri ile getirilen 8 yasindaki erkek alman coban kopegi olusturdu. Kopegin klinik muayenesinde, beden isisinda artis, tirnaklarda uzama ve deformasyonla birlikte burun kanamasi belirlendi. Bu bulgulara dayanarak Leishmaniasis’den suphe edildi. Leishmania spp. yonunden yapilan hizli test kiti (Leish® speed) ile hastaligin pozitif, IFAT (indirekt immunofloresan antikor testi) ile de 1/256 titre de pozitif oldugu saptandi. Bu olgu ile Amasya ilinde ilk defa bir kopekte visseral leishmaniasis bildirilmektedir
OZET: Bu calisma, Ankara sokak kopeklerinde toksoplazmozisin seroprevalansini saptamak amaciyla y... more OZET: Bu calisma, Ankara sokak kopeklerinde toksoplazmozisin seroprevalansini saptamak amaciyla yapilmistir. Degisik yas gruplarinda ve melez irktan toplam 107 sokak kopeginden kan ornegi alindi. Kopeklerin genel klinik muayeneleri yapilarak veriler kaydedildi. Serum ornekleri, Anti-Toxoplasma gondii (T. gondii) antikorlari yonunden Sabin Feldman Dye Testi (SFDT) ile calisildi. SFDT'inde 1/16 ve uzeri titreler pozitif olarak degerlendirildi. SFDT ile T. gondii antikorlari arastirilan 107 kopegin 58'si (%54) 1/16 ve uzerindeki titrelerde seropozitif bulunurken, 49'unun (%46) seronegatif oldugu tespit edildi. Seropozitif olan 58 kopegin antikor titreleri 16'sinda 1/16, 12'sinde 1/64, 15’inde 1/256, 15'inde 1/1024 olarak saptandi. Bu veriler, Ankara'dan orneklenen sokak kopeklerinde T. gondii'nin yaygin oldugunu gostermektedir.
Background/aim: This prospective study aimed to determine the presence of the most common carbape... more Background/aim: This prospective study aimed to determine the presence of the most common carbapenemase genes, blaOXA-48, blaKPC, blaIMP, blaVIM and blaNDM on carbapenem resistant clinical K.pneumoniae and E.coli isolates. Materials and methods: Isolates were selected according to EUCAST guideline; gradient test and disc diffusion with both meropenem and ertapenem discs. Resistance rates of these isolates to other antimicrobial agents were also examined by disc diffusion method. Carbapenem resistance gene were investigated by using Real-Time PCR. Results: A total of 3845 E. coli and 1689 K.pneumoniae isolates from clinical samples between January 2015 and April 2017 were evaluated. The 419 isolates were found as carbapenem resistant but only the first resistant isolate (n=155; 126 K.pneumoniae and 29 E.coli) of each patient were included. Carbapenem resistant isolates were most frequently isolated from intensive care units (48.8%). Colistin was the most effective antibiotic (91.0%)....
Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and dive... more Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. In recent years, tularemia cases are increasing in Turkey, with a special attention to Marmara, western Blacksea and Central Anatolia regions. The aim of this study was to evaluate tularemia cases admitted to our hospital during an outbreak emerged at Central Anatolia between December 2009 and September 2010, making a point for the disease. A total of 32 patients (17 female, 15 male; age range: 15-80 years, mean age: 41 ± 16 years) with fever, sore throat, cervical mass and failure to respond to beta-lactam antibiotics, were followed up with the preliminary diagnosis of tularemia. The diagnosis was confirmed by specific laboratory tests. Serum samples were obtained from 25 patients and in 17 (68%) of them microagglutination test yielded positive result (≥ 1/160) in their first serum samples. All of the 8 patients who had negative results in their first sample...
Shortly after the first detection of human immundeficiency virus (HIV) infection in USA in 1981, ... more Shortly after the first detection of human immundeficiency virus (HIV) infection in USA in 1981, the number of cases have increased gradually from all around the world. Turkey’s high capacity for tourism and the unique geographic location extending between Europe and Asia, provides convenience for the passage of individuals across the countries and sexually transmitted infections including HIV, as well. According to the official data of the Ministry of Health; there are 25809 HIV positive and 1958 AIDS cases as of November 30, 2020, after the epidemic started in 1985 in Turkey. Despite the decrease in the number of newly detected HIV cases as a result of serious measures taken for the transmission of infection worldwide, the increase in the number of cases still continues in our country. Shortening the reporting period and starting treatment as soon as possible in the diagnosis of infection is critical for the control of the epidemic. For this purpose, Centers for Disease Control an...
Background Brucellosis is a worldwide zoonotic disease that causes serious public health problems... more Background Brucellosis is a worldwide zoonotic disease that causes serious public health problems. This study aimed to identify Brucella strains isolated from various clinical samples by conventional and molecular methods and to determine antimicrobial susceptibilities against doxycycline (DOX), streptomycin (STR), ciprofloxacin (CIP) and rifampicin (RIF) by the gradient strip (E test) test method. Methods A total of 87 Brucella strains isolated from various clinical specimens between 2004 and 2018 were included in this study. While four of the 87 strains included in the study were identified only at the genus level, the remaining 83 strains were identified at the species level by the Real-Time Multiplex PCR (M-RT-PCR) method and conventional methods were used for biotyping. Results According to molecular identification results, 83 strains were identified as B. melitensis by the M-RT-PCR method, with 82 strains identified as Brucella melitensis biovar (bv) 3 and one as B. melitensis...
Bu calismanin hayvan materyalini, klinigimize derisinde uzun sureli iyilesmeyen yaralar ve kronik... more Bu calismanin hayvan materyalini, klinigimize derisinde uzun sureli iyilesmeyen yaralar ve kronik burun kanamasi sikayetleri ile getirilen 8 yasindaki erkek alman coban kopegi olusturdu. Kopegin klinik muayenesinde, beden isisinda artis, tirnaklarda uzama ve deformasyonla birlikte burun kanamasi belirlendi. Bu bulgulara dayanarak Leishmaniasis’den suphe edildi. Leishmania spp. yonunden yapilan hizli test kiti (Leish® speed) ile hastaligin pozitif, IFAT (indirekt immunofloresan antikor testi) ile de 1/256 titre de pozitif oldugu saptandi. Bu olgu ile Amasya ilinde ilk defa bir kopekte visseral leishmaniasis bildirilmektedir
OZET: Bu calisma, Ankara sokak kopeklerinde toksoplazmozisin seroprevalansini saptamak amaciyla y... more OZET: Bu calisma, Ankara sokak kopeklerinde toksoplazmozisin seroprevalansini saptamak amaciyla yapilmistir. Degisik yas gruplarinda ve melez irktan toplam 107 sokak kopeginden kan ornegi alindi. Kopeklerin genel klinik muayeneleri yapilarak veriler kaydedildi. Serum ornekleri, Anti-Toxoplasma gondii (T. gondii) antikorlari yonunden Sabin Feldman Dye Testi (SFDT) ile calisildi. SFDT'inde 1/16 ve uzeri titreler pozitif olarak degerlendirildi. SFDT ile T. gondii antikorlari arastirilan 107 kopegin 58'si (%54) 1/16 ve uzerindeki titrelerde seropozitif bulunurken, 49'unun (%46) seronegatif oldugu tespit edildi. Seropozitif olan 58 kopegin antikor titreleri 16'sinda 1/16, 12'sinde 1/64, 15’inde 1/256, 15'inde 1/1024 olarak saptandi. Bu veriler, Ankara'dan orneklenen sokak kopeklerinde T. gondii'nin yaygin oldugunu gostermektedir.
Background/aim: This prospective study aimed to determine the presence of the most common carbape... more Background/aim: This prospective study aimed to determine the presence of the most common carbapenemase genes, blaOXA-48, blaKPC, blaIMP, blaVIM and blaNDM on carbapenem resistant clinical K.pneumoniae and E.coli isolates. Materials and methods: Isolates were selected according to EUCAST guideline; gradient test and disc diffusion with both meropenem and ertapenem discs. Resistance rates of these isolates to other antimicrobial agents were also examined by disc diffusion method. Carbapenem resistance gene were investigated by using Real-Time PCR. Results: A total of 3845 E. coli and 1689 K.pneumoniae isolates from clinical samples between January 2015 and April 2017 were evaluated. The 419 isolates were found as carbapenem resistant but only the first resistant isolate (n=155; 126 K.pneumoniae and 29 E.coli) of each patient were included. Carbapenem resistant isolates were most frequently isolated from intensive care units (48.8%). Colistin was the most effective antibiotic (91.0%)....
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