Lung cancer is the leading cause of cancer death in the US with ∼124,000 new cases annually, and ... more Lung cancer is the leading cause of cancer death in the US with ∼124,000 new cases annually, and a five year survival rate of ∼16%. Mutant KRAS-driven lung adenocarcinoma (KRAS LADC) is a particularly prevalent and deadly form of lung cancer. Protein kinase Cι (PKCι) is an oncogenic effector of KRAS that activates multiple signaling pathways that stimulate transformed growth and invasion, and maintain a KRAS LADC tumor-initiating cell (TIC) phenotype. PKCι inhibitors used alone and in strategic combination show promise as new therapeutic approaches to treatment of KRAS LADC. These novel drug combinations may improve clinical management of KRAS LADC.
Till date, wireless technology was a patchwork of incompatible system from a variety of vendors. ... more Till date, wireless technology was a patchwork of incompatible system from a variety of vendors. The technology was slow, expensive and reserved for mobile situation or hostile environments where cabling was impractical or impossible. In recent years, Zigbee has becoming one of the most promising protocols for wireless networking. Consequently, interoperation with Zigbee-enabled home network devices such as wireless sensor and appliances is an essential functionality in gateway systems. With maturity of industry standards and the deployment of lightweight wireless networking hardware across a broad market section, wireless technology has come of age and Zigbee is a new player in the field. This paper gives an overview of Zigbee's technical attributes, applications, products and its future and its application network in detail.
Lung cancer is the leading cause of cancer death in the US with ∼124,000 new cases annually, and ... more Lung cancer is the leading cause of cancer death in the US with ∼124,000 new cases annually, and a five year survival rate of ∼16%. Mutant KRAS-driven lung adenocarcinoma (KRAS LADC) is a particularly prevalent and deadly form of lung cancer. Protein kinase Cι (PKCι) is an oncogenic effector of KRAS that activates multiple signaling pathways that stimulate transformed growth and invasion, and maintain a KRAS LADC tumor-initiating cell (TIC) phenotype. PKCι inhibitors used alone and in strategic combination show promise as new therapeutic approaches to treatment of KRAS LADC. These novel drug combinations may improve clinical management of KRAS LADC.
Till date, wireless technology was a patchwork of incompatible system from a variety of vendors. ... more Till date, wireless technology was a patchwork of incompatible system from a variety of vendors. The technology was slow, expensive and reserved for mobile situation or hostile environments where cabling was impractical or impossible. In recent years, Zigbee has becoming one of the most promising protocols for wireless networking. Consequently, interoperation with Zigbee-enabled home network devices such as wireless sensor and appliances is an essential functionality in gateway systems. With maturity of industry standards and the deployment of lightweight wireless networking hardware across a broad market section, wireless technology has come of age and Zigbee is a new player in the field. This paper gives an overview of Zigbee's technical attributes, applications, products and its future and its application network in detail.
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Papers by Syed Amjed Ali