The Presented paper is based on a case study realised in a huge service and production company, w... more The Presented paper is based on a case study realised in a huge service and production company, which produces plastics wares. Conducted researches were connected with efficiency level of project implementation, which regarded using Lean Manufacturing methodology. Authors analysed implementation range of methods and tools connected with Lean methodology, such as: 5S, SMED, TPM, Hoshin Kanri, Kaizen and Kanban as well as their meaning to elimination of various types of wastes. In the context of goals established by the company regarding implementation of Lean methodology, range of elimination of various types of mismanagement were evaluated in relation to range of using particular tools and methods. The results came out to be unrewarding. The cause of such results was not observed in a mode and range of introduction individual tools and methods, but in their synergic cooperation.
Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncolog... more Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is still being conducted. The aim of this study was to evaluate serum levels of caspase-3, caspase-8, and caspase-9 in women with ovarian cancer. Patients with ovarian serous cystadenoma (Cystadenoma serosum) and papillary serous cystadenocarcinoma (Cystadenocarcinoma papillare serosum IIIC) were included in the study, as well as healthy women who constituted the control group. The results of the study revealed a statistically significantly decreased mean serum levels of caspase-3, caspase-8, and caspase-9 in women with ovarian cancer as compared to the control group (p ˂ 0.001), which indicates the involvement of the studied parameters in immune system disturbances occurring in the process of apoptosis by the extrinsic and intrinsic pat...
The Presented paper is based on a case study realised in a huge service and production company, w... more The Presented paper is based on a case study realised in a huge service and production company, which produces plastics wares. Conducted researches were connected with efficiency level of project implementation, which regarded using Lean Manufacturing methodology. Authors analysed implementation range of methods and tools connected with Lean methodology, such as: 5S, SMED, TPM, Hoshin Kanri, Kaizen and Kanban as well as their meaning to elimination of various types of wastes. In the context of goals established by the company regarding implementation of Lean methodology, range of elimination of various types of mismanagement were evaluated in relation to range of using particular tools and methods. The results came out to be unrewarding. The cause of such results was not observed in a mode and range of introduction individual tools and methods, but in their synergic cooperation.
Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncolog... more Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is still being conducted. The aim of this study was to evaluate serum levels of caspase-3, caspase-8, and caspase-9 in women with ovarian cancer. Patients with ovarian serous cystadenoma (Cystadenoma serosum) and papillary serous cystadenocarcinoma (Cystadenocarcinoma papillare serosum IIIC) were included in the study, as well as healthy women who constituted the control group. The results of the study revealed a statistically significantly decreased mean serum levels of caspase-3, caspase-8, and caspase-9 in women with ovarian cancer as compared to the control group (p ˂ 0.001), which indicates the involvement of the studied parameters in immune system disturbances occurring in the process of apoptosis by the extrinsic and intrinsic pat...
Uploads