Aim: Freshwater snails of the genus Bulinus act as essential intermediate hosts of Schistosoma ha... more Aim: Freshwater snails of the genus Bulinus act as essential intermediate hosts of Schistosoma haematobium, a trematode parasite that causes urogenital schistosomiasis. The snails are widely distributed throughout Nigerian waters. Since species identification of the Bulinus snails is important for appropriate control strategies of urogenital schistosomiasis, this study therefore aimed at identifying the Bulinus species responsible for transmission of the infection in four communities located in an endemic Local Government Area of Nigeria. It also aimed at using restriction fragment length polymorphism (RFLP) as a more affordable method than sequencing to characterize Bulinus snails from schistosomiasis endemic regions in Nigeria. Methods: In this study, 100 freshwater snails morphologically identified as Bulinus species were collected from four communities located in a previously reported schistosomiasis endemic Local Government Area (LGA), namely Olorunda LGA in Oshun State, Southw...
Background: Schistosomiasis causes anaemia, stunting, and cognitive impairment in children, which... more Background: Schistosomiasis causes anaemia, stunting, and cognitive impairment in children, which impairs school performance. Government coordinated school-based preventive chemotherapy with donated praziquantel has been primarily used for schistosomiasis control in Ogun State, necessitating the need to monitor treatment coverage and its effect on schistosomiasis burden. Methods: We screened 422 pupils aged 1-14 years old for Schistosoma haematobium in June 2018 using the filtration technique. KAP data and socio-demographic characteristics of participants were also recorded. Results: Out of 422 screened pupils, 59 (14%) tested positive using the filtration method. Peak prevalence (31.6%) occurred in pupils under five years. Heavy infection intensity occurred in 3.4% of the infected population. KAP studies revealed that 55% knew schistosomiasis was linked to urinating blood. Symptoms experienced main-ly were diarrhoea (44.6%), stomach ache (29.7 %), and fever (13.5 %). Pipe-borne wat...
Introduction: Buruli ulcer (BU) caused by Mycobacterium ulcerans is a severe, necrotizing disease... more Introduction: Buruli ulcer (BU) caused by Mycobacterium ulcerans is a severe, necrotizing disease affecting the skin, subcutaneous adipose tissue and occasionally bones. This neglected tropical infection was regarded as an emerging infectious disease by the World Health Organization (WHO) in 1998. BU, as the third most common mycobacterial disease after tuberculosis and leprosy, has been reported in more than 30 countries worldwide. The disease is characterized by the production of mycolactone which is thought to be responsible for the large ulcers associated with this disease. The mode of transmission is poorly understood but the controversial role of aquatic insects and mosquitoes has been proposed. This study, as a part of an ongoing research project, is aimed at determining the genomic epidemiology of Buruli ulcer disease (BUD) in southwest, Nigeria. Methodology: Community-based sensitization awareness and an active case search involving the identification of suspected cases of ...
S OF PLENARY PRESENTATIONS A3 ABSTRACTS OF ORAL PRESENTATIONS A5S OF ORAL PRESENTATIONS A5 ABSTRA... more S OF PLENARY PRESENTATIONS A3 ABSTRACTS OF ORAL PRESENTATIONS A5S OF ORAL PRESENTATIONS A5 ABSTRACTS OF POSTER PRESENTATIONS A16S OF POSTER PRESENTATIONS A16
Human toxocariasis is caused by the nematode, Toxocara canis and it is a poorly understood phenom... more Human toxocariasis is caused by the nematode, Toxocara canis and it is a poorly understood phenomenon in Nigeria. Seroepidemiological studies have not been previously carried out among the preschool aged children in Nigeria. A cross-sectional study was conducted in pre-school children in four communities from Osun State, Nigeria between January and July 2016. A total of 308 children Aged 9 months and 5 years were studied comprising 53.2% (164/308) male and 46.8% (144/308) female. Blood samples were collected and screened for the presence of anti-Toxocara IgG antibodies by Western blot analysis based on the excretory-secretory antigens of larva T. canis (TcES), targeting low molecular weight bands of 24 - 35kDa specific for T. canis. Questionnaires were given to parents/guardians of the studied children to collect information regarding relationship between infection and host factors. The overall seroprevalence of Toxocara infection was 37.3%. The seroprevalence in the studied prescho...
Aim: Freshwater snails of the genus Bulinus act as essential intermediate hosts of Schistosoma ha... more Aim: Freshwater snails of the genus Bulinus act as essential intermediate hosts of Schistosoma haematobium, a trematode parasite that causes urogenital schistosomiasis. The snails are widely distributed throughout Nigerian waters. Since species identification of the Bulinus snails is important for appropriate control strategies of urogenital schistosomiasis, this study therefore aimed at identifying the Bulinus species responsible for transmission of the infection in four communities located in an endemic Local Government Area of Nigeria. It also aimed at using restriction fragment length polymorphism (RFLP) as a more affordable method than sequencing to characterize Bulinus snails from schistosomiasis endemic regions in Nigeria. Methods: In this study, 100 freshwater snails morphologically identified as Bulinus species were collected from four communities located in a previously reported schistosomiasis endemic Local Government Area (LGA), namely Olorunda LGA in Oshun State, Southw...
Background: Schistosomiasis causes anaemia, stunting, and cognitive impairment in children, which... more Background: Schistosomiasis causes anaemia, stunting, and cognitive impairment in children, which impairs school performance. Government coordinated school-based preventive chemotherapy with donated praziquantel has been primarily used for schistosomiasis control in Ogun State, necessitating the need to monitor treatment coverage and its effect on schistosomiasis burden. Methods: We screened 422 pupils aged 1-14 years old for Schistosoma haematobium in June 2018 using the filtration technique. KAP data and socio-demographic characteristics of participants were also recorded. Results: Out of 422 screened pupils, 59 (14%) tested positive using the filtration method. Peak prevalence (31.6%) occurred in pupils under five years. Heavy infection intensity occurred in 3.4% of the infected population. KAP studies revealed that 55% knew schistosomiasis was linked to urinating blood. Symptoms experienced main-ly were diarrhoea (44.6%), stomach ache (29.7 %), and fever (13.5 %). Pipe-borne wat...
Introduction: Buruli ulcer (BU) caused by Mycobacterium ulcerans is a severe, necrotizing disease... more Introduction: Buruli ulcer (BU) caused by Mycobacterium ulcerans is a severe, necrotizing disease affecting the skin, subcutaneous adipose tissue and occasionally bones. This neglected tropical infection was regarded as an emerging infectious disease by the World Health Organization (WHO) in 1998. BU, as the third most common mycobacterial disease after tuberculosis and leprosy, has been reported in more than 30 countries worldwide. The disease is characterized by the production of mycolactone which is thought to be responsible for the large ulcers associated with this disease. The mode of transmission is poorly understood but the controversial role of aquatic insects and mosquitoes has been proposed. This study, as a part of an ongoing research project, is aimed at determining the genomic epidemiology of Buruli ulcer disease (BUD) in southwest, Nigeria. Methodology: Community-based sensitization awareness and an active case search involving the identification of suspected cases of ...
S OF PLENARY PRESENTATIONS A3 ABSTRACTS OF ORAL PRESENTATIONS A5S OF ORAL PRESENTATIONS A5 ABSTRA... more S OF PLENARY PRESENTATIONS A3 ABSTRACTS OF ORAL PRESENTATIONS A5S OF ORAL PRESENTATIONS A5 ABSTRACTS OF POSTER PRESENTATIONS A16S OF POSTER PRESENTATIONS A16
Human toxocariasis is caused by the nematode, Toxocara canis and it is a poorly understood phenom... more Human toxocariasis is caused by the nematode, Toxocara canis and it is a poorly understood phenomenon in Nigeria. Seroepidemiological studies have not been previously carried out among the preschool aged children in Nigeria. A cross-sectional study was conducted in pre-school children in four communities from Osun State, Nigeria between January and July 2016. A total of 308 children Aged 9 months and 5 years were studied comprising 53.2% (164/308) male and 46.8% (144/308) female. Blood samples were collected and screened for the presence of anti-Toxocara IgG antibodies by Western blot analysis based on the excretory-secretory antigens of larva T. canis (TcES), targeting low molecular weight bands of 24 - 35kDa specific for T. canis. Questionnaires were given to parents/guardians of the studied children to collect information regarding relationship between infection and host factors. The overall seroprevalence of Toxocara infection was 37.3%. The seroprevalence in the studied prescho...
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