Polyetheretherketone (PEEK) has the potential to overcome some of the disadvantages of titanium i... more Polyetheretherketone (PEEK) has the potential to overcome some of the disadvantages of titanium interbody implants in anterior cervical and discectomy and fusion (ACDF). However, PEEK shows an inferior biological behavior regarding osseointegration and bioactivity. Therefore, the aim of the study was to create a bioactive surface coating on PEEK implants with a unique nanopore structure enabling the generation of a long-lasting interfacial composite layer between coating material and implant. Seventy-two PEEK implants—each thirty-six pure PEEK implants (PI) and thirty-six PEEK implants with a sprayed coating consisting of nanocrystalline hydroxyapatite (ncHA) embedded in a silica matrix and interfacial composite layer (SPI)—were inserted in the femoral condyles of adult rats using a split-side model. After 2, 4 and 8 weeks, the femur bones were harvested. Half of the femur bones were used in histological and histomorphometrical analyses. Additionally, pull-out tests were performed i...
Polyetheretherketon (PEEK) ersetzt als Implantatmaterial bereits in verschiedenen medizinischen A... more Polyetheretherketon (PEEK) ersetzt als Implantatmaterial bereits in verschiedenen medizinischen Anwendungen metallische Werkstoffe. Trotz seiner hervorragenden Biokompatibilitat, fordert es jedoch keinen direkten Verbund mit Knochen. Um diese Eigenschaft langfristig zu verbessern, wurde eine Kompositschicht zwischen einem hochporosen Knochenersatzmaterial und PEEK hergestellt. In diesem Zusammenhang wurden Glasubergang und Kristallisation des Polymers in den Nanoporen eines Modellsystems aus SiO2-PEEK-Kompositen und die biologische Leistungsfahigkeit eines Modellimplantats untersucht.
Polyetheretherketone (PEEK) has the potential to overcome some of the disadvantages of titanium i... more Polyetheretherketone (PEEK) has the potential to overcome some of the disadvantages of titanium interbody implants in anterior cervical and discectomy and fusion (ACDF). However, PEEK shows an inferior biological behavior regarding osseointegration and bioactivity. Therefore, the aim of the study was to create a bioactive surface coating on PEEK implants with a unique nanopore structure enabling the generation of a long-lasting interfacial composite layer between coating material and implant. Seventy-two PEEK implants—each thirty-six pure PEEK implants (PI) and thirty-six PEEK implants with a sprayed coating consisting of nanocrystalline hydroxyapatite (ncHA) embedded in a silica matrix and interfacial composite layer (SPI)—were inserted in the femoral condyles of adult rats using a split-side model. After 2, 4 and 8 weeks, the femur bones were harvested. Half of the femur bones were used in histological and histomorphometrical analyses. Additionally, pull-out tests were performed i...
Polyetheretherketon (PEEK) ersetzt als Implantatmaterial bereits in verschiedenen medizinischen A... more Polyetheretherketon (PEEK) ersetzt als Implantatmaterial bereits in verschiedenen medizinischen Anwendungen metallische Werkstoffe. Trotz seiner hervorragenden Biokompatibilitat, fordert es jedoch keinen direkten Verbund mit Knochen. Um diese Eigenschaft langfristig zu verbessern, wurde eine Kompositschicht zwischen einem hochporosen Knochenersatzmaterial und PEEK hergestellt. In diesem Zusammenhang wurden Glasubergang und Kristallisation des Polymers in den Nanoporen eines Modellsystems aus SiO2-PEEK-Kompositen und die biologische Leistungsfahigkeit eines Modellimplantats untersucht.
Uploads
Papers by Thomas Frankenberger